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Drimendiol

Drimendiol Structure
Drimendiol structure
CAS No.
34437-62-2
Chemical Name:
Drimendiol
Synonyms
Drimendiol;(1R,4aS,8aS)-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-1,2-naphthalenedimethanol;1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-, (1R,4aS,8aS)-;((1r,4As,8as)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalene-1,2-diyl)dimethanol
CBNumber:
CB76197882
Molecular Formula:
C15H26O2
Molecular Weight:
238.37
MDL Number:
MFCD33021214
MOL File:
34437-62-2.mol
Last updated:2023-05-21 10:59:17
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Drimendiol Properties

Melting point 73.5-74.5 °C
Boiling point 352.7±17.0 °C(Predicted)
Density 0.993±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form A solid
pka 14.82±0.10(Predicted)

Drimendiol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 3874CS Drimendiol 34437-62-2 1mg $403 2021-12-16 Buy
Product number Packaging Price Buy
3874CS 1mg $403 Buy

Drimendiol Chemical Properties,Uses,Production

Description

Drimendiol is a sesquiterpene that has been found in W. ugandensis.1 It inhibits C. albicans, S. aureus, and S. epidermidis biofilm formation with 50% biofilm inhibitory concentration values (BIC50s) of 25.5, 65.1, and 67.1 μg/ml, respectively. It has antifouling activity, inhibiting the settlement of C. savignyi and B. improvisus larvae on a petri dish surface (EC50s = 1 and 0.5 μg/ml, respectively).2

Definition

ChEBI: Drimendiol is a member of the class of octahydronaphthalenes that is drimenol in which a hydrogen of the allylic methyl group has been replaced by a hydroxy group. It has a role as a quorum sensing inhibitor and a plant metabolite. It is a member of octahydronaphthalenes, a sesquiterpenoid, a homoallylic alcohol and an allylic alcohol. It is functionally related to a drimenol. It derives from a hydride of a drimane.

References

1. Kipanga, P.N., Liu, M., Panda, S.K., et al. Biofilm inhibiting properties of compounds from the leaves of Warburgia ugandensis Sprague subsp ugandensis against Candida and staphylococcal biofilms J. Ethnopharmacol. 248:112352,(2020).
2. Moodie, L.W., Trepos, R., Cervin, G., et al. Probing the structure-activity relationship of the natural antifouling agent polygodial against both micro- and macrofoulers by semisynthetic modification J. Nat. Prod. 80(2),515-525(2017).

Drimendiol Preparation Products And Raw materials

Raw materials

Preparation Products

Drimendiol Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8864 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
Supplier Advantage
Aladdin Scientific 		58
BOC Sciences 65
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Meng Cheng Technology (Shanghai) Co., LTD 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
Drimendiol 1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-, (1R,4aS,8aS)- (1R,4aS,8aS)-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-1,2-naphthalenedimethanol ((1r,4As,8as)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalene-1,2-diyl)dimethanol 34437-62-2