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3-FLUORO-4-HYDROXYPYRIDINE

CAS No.
22282-73-1
Chemical Name:
3-FLUORO-4-HYDROXYPYRIDINE
Synonyms
3-Fluoropyridin-4-ol;3-FLUORO-4-PYRIDINOL;4-Pyridinol, 3-fluoro-;3-fluoro-1H-pyridin-4-one;3-fluoropyridin-4(1H)-one;3-FLUORO-4-HYDROXYPYRIDINE;3-Fluoro-4-hydroxypyridine97%;3-FLUORO-4-HYDROXYPYRIDINE 97%;3-FLUORO-4-HYDROXYPYRIDINE ISO 9001:2015 REACH
CBNumber:
CB7680719
Molecular Formula:
C5H4FNO
Molecular Weight:
113.09
MDL Number:
MFCD04114240
MOL File:
22282-73-1.mol
Last updated:2025-07-24 18:13:48
Product description Number Pack Size Price
3-Fluoro-4-hydroxypyridine F597433 250mg $55
3-Fluoro-4-hydroxypyridine F597433 1g $75
3-FLUORO-4-HYDROXYPYRIDINE 95.00% HCH0012546 1G $994.46
3-Fluoropyridin-4-ol 95+% PC201201 1g $66
3-Fluoro-4-hydroxypyridine W4594 250mg $28
More product size

3-FLUORO-4-HYDROXYPYRIDINE Properties

Melting point 153 °C
Boiling point 315.8±22.0 °C(Predicted)
Density 1.325±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 3.99±0.18(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933399990

3-FLUORO-4-HYDROXYPYRIDINE price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F597433 3-Fluoro-4-hydroxypyridine 22282-73-1 250mg $55 2021-12-16 Buy
TRC F597433 3-Fluoro-4-hydroxypyridine 22282-73-1 1g $75 2021-12-16 Buy
American Custom Chemicals Corporation HCH0012546 3-FLUORO-4-HYDROXYPYRIDINE 95.00% 22282-73-1 1G $994.46 2021-12-16 Buy
Apolloscientific PC201201 3-Fluoropyridin-4-ol 95+% 22282-73-1 1g $66 2021-12-16 Buy
AK Scientific W4594 3-Fluoro-4-hydroxypyridine 22282-73-1 250mg $28 2021-12-16 Buy
Product number Packaging Price Buy
F597433 250mg $55 Buy
F597433 1g $75 Buy
HCH0012546 1G $994.46 Buy
PC201201 1g $66 Buy
W4594 250mg $28 Buy

3-FLUORO-4-HYDROXYPYRIDINE Chemical Properties,Uses,Production

Synthesis

3-FLUOROPYRIDINE-4-BORONIC ACID

458532-97-3

3-FLUORO-4-HYDROXYPYRIDINE

22282-73-1

The general procedure for the synthesis of 3-fluoro-4-hydroxypyridine from 3-fluoropyridine-4-boronic acid was as follows: under standard reaction conditions, CuSO4-5H2O (0.049 g, 0.2 mmol) and 6.7 mol% acetamide (20 mg) were dissolved in methanol, followed by addition of 2 mmol of phenylboronic acid. The reaction mixture was placed in an oil bath preheated to 60 °C and kept under constant stirring at atmospheric pressure. The reaction progress was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was washed twice with hot ethyl acetate to remove unreacted reactants and by-products. After removal of hot ethyl acetate by evaporation, the crude product was purified by column chromatography on silica gel (260 mesh) with an eluent ratio of petroleum ether:ethyl acetate (25:75). The recovered catalyst could be used directly in the next round of reaction. The final product was structurally confirmed by 1H NMR and 13C NMR spectra.

References

[1] Journal of Molecular Catalysis A: Chemical, 2014, vol. 395, p. 500 - 505

2247-88-3
22282-73-1
Synthesis of 3-FLUORO-4-HYDROXYPYRIDINE from 4-Amino-3-fluoropyridine

3-FLUORO-4-HYDROXYPYRIDINE Preparation Products And Raw materials

Global( 95)Suppliers
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career henan chemical co
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Shenzhen Nexconn Pharmatechs Ltd
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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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Hefei TNJ Chemical Industry Co.,Ltd.
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ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 8026 58

View Lastest Price from 3-FLUORO-4-HYDROXYPYRIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-FLUORO-4-HYDROXYPYRIDINE pictures 2025-06-25 3-FLUORO-4-HYDROXYPYRIDINE
22282-73-1
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
3-FLUORO-4-HYDROXYPYRIDINE pictures 2019-07-06 3-FLUORO-4-HYDROXYPYRIDINE
22282-73-1
US $1.00 / KG 1KG 99% Customized Career Henan Chemical Co

3-FLUORO-4-HYDROXYPYRIDINE Spectrum

3-FLUORO-4-HYDROXYPYRIDINE 3-FLUORO-4-PYRIDINOL 3-Fluoro-4-hydroxypyridine97% 3-FLUORO-4-HYDROXYPYRIDINE 97% 3-Fluoropyridin-4-ol 3-fluoropyridin-4(1H)-one 3-fluoro-1H-pyridin-4-one 4-Pyridinol, 3-fluoro- 3-FLUORO-4-HYDROXYPYRIDINE ISO 9001:2015 REACH 22282-73-1 Pyridines