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(±)-Cloprostenol sodium salt

CAS No.
55028-72-3
Chemical Name:
(±)-Cloprostenol sodium salt
Synonyms
CLOPROSTENOL SODIUM;D-Cloprostenol sodiuM;DL-Cloprostenol sodiuM;16-(3-CHLOROPHENOXY)-9,11,15R-TRIHYDROXY-17,18,19,20-TETRANORPROSTA-5Z,13E-DIEN-1-OIC ACID SODIUM SALT;sodium(Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate;Ciosin;Planate;Estrumat;CLOPROSTENOL NA;15(S)-CLOPROSTENOL
CBNumber:
CB7699245
Molecular Formula:
C22H30ClNaO6
Molecular Weight:
448.92
MDL Number:
MFCD00132875
MOL File:
55028-72-3.mol
Last updated:2023-11-07 16:56:45

(±)-Cloprostenol sodium salt Properties

Melting point 68-70 °C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility H2O: >10 mg/mL
form solid
color light brown
InChIKey IFEJLMHZNQJGQU-KXXGZHCCSA-M
CAS DataBase Reference 55028-72-3(CAS DataBase Reference)
FDA UNII 886SAV9675

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H315-H319-H335-H361
Precautionary statements  P201-P301+P312+P330-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  T
Risk Statements  60-22-36/37/38
Safety Statements  53-26-36/37/39-45
WGK Germany  3
HS Code  2937500000

(±)-Cloprostenol sodium salt price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C6116 (+/-)-Cloprostenol sodium salt hydrate ≥98% (HPLC), powder 55028-72-3 1mg $93.3 2024-03-01 Buy
Sigma-Aldrich C6116 (+/-)-Cloprostenol sodium salt hydrate ≥98% (HPLC), powder 55028-72-3 5mg $372 2024-03-01 Buy
Sigma-Aldrich 1140666 Cloprostenol sodium United States Pharmacopeia (USP) Reference Standard 55028-72-3 400mg $3790 2024-03-01 Buy
Sigma-Aldrich BP628 Cloprostenol sodium British Pharmacopoeia (BP) Reference Standard 55028-72-3 50MG $263 2023-06-20 Buy
Cayman Chemical 16764 Cloprostenol (sodium salt) ≥98% 55028-72-3 1mg $57 2024-03-01 Buy
Product number Packaging Price Buy
C6116 1mg $93.3 Buy
C6116 5mg $372 Buy
1140666 400mg $3790 Buy
BP628 50MG $263 Buy
16764 1mg $57 Buy

(±)-Cloprostenol sodium salt Chemical Properties,Uses,Production

Description

±)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol (C587300), an aryl-oxymethyl analog of prostaglandin F2α.

Uses

(±)-Cloprostenol sodium salt is a prostaglandin that dissolves the corpus luteum of cattle and is used as a veterinary drug.

brand name

Estrumate(Bayer Animal Health).

General Description

Cloprostenol sodium (Estrumate)is available as the sodium salt from Bayer AgriculturalDivision or Bayvet Division of Miles Laboratory as an aqueoussolution containing 250 mg/mL.

Biological Activity

Water-soluble prostaglandin F 2 α (PGF 2 α ) analog; acts as a potent FP receptor agonist (EC 50 = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo .

Side effects

A low incidence of clostridial and other infections at the injection site has been reported following prostaglandin administration. Treated animals should be closely observed post injection and appropriate antibiotic therapy initiated at the first sign(s) of infection.
Very rarely, anaphylactic reactions have occurred after administration of the product. Overdose: At 50 and 100 times the recommended dose of cloprostenol mild side effects may be detected. These include increased uneasiness, mild transient diarrhea, slight frothing, and milk letdown.

Veterinary Drugs and Treatments

Cloprostenol is approved for use in beef or dairy cattle to induce luteolysis. It is recommended by the manufacturer for unobserved or undetected estrus in cows cycling normally, pyometra or chronic endometritis, expulsion of mummified fetus, luteal cysts, induced abortions after mismating, and to schedule estrus and ovulation for controlled breeding.
Cloprostenol has been used in dogs for pregnancy termination and treatment of open pyometra. The use of cloprostenol for pyometra is controversial as some believe dinoprost (PGF2alpha) is more effective and has fewer adverse effects than cloprostenol.

Solubility in water

Soluble in H2O.

(±)-Cloprostenol sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 223)Suppliers
Supplier Tel Email Country ProdList Advantage
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Shanghai finete Pharmaceutical Co., Ltd.
+86-18221039705 CHINA 139 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
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Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Beijing Yibai Biotechnology Co., Ltd
0086-182-6772-3597 sales04@yibaibiotech.com CHINA 419 58

View Lastest Price from (±)-Cloprostenol sodium salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DL-Cloprostenol Sodium pictures 2024-04-22 DL-Cloprostenol Sodium
55028-72-3
US $0.00 / KG 2KG 98% up, GMP, DMF 20 tons Sinoway Industrial co., ltd.
Cloprostenol Sodium pictures 2024-03-08 Cloprostenol Sodium
55028-72-3
US $10.00 / kg 1kg 99% 1000kg Nantong Guangyuan Chemicl Co,Ltd
(±)-Cloprostenol sodium salt pictures 2023-11-27 (±)-Cloprostenol sodium salt
55028-72-3
US $15.00 / gram 10gram 99% 50000 kilograms Wuhan Senwayer Century Chemical Co.,Ltd
15-EPI CLOPROSTENOL 15(S)-CLOPROSTENOL (+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA SODIUM SALT 7-(2-[4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl)-5-heptenoic acid (5Z)-rel-Cloprostenol SodiuM (+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid hydrate sodium salt (+/-)-Cloprostenol hydrate sodium salt (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoicacidmonosodiumsalt (+/-)-Cloprostenol sodium salt hydrate,(+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid sodium salt hydrate Cloprostenol Sodium (400 mg) DL-Cloprostenol Sodium Salt (+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid sodium salt hydrate Cloprostenol sodium, >=99% 7-[-2-[4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid sodium salt 16-(M-CHLOROPHENOXY)-TETRANOR-PROSTAGLANDIN-F2ALPHA, SODIUM SALT (+/-)-9ALPHA,11ALPHA,15-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT (+/-)-9ALPHA,11ALPHA,15S-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID (+)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT 7-(2-[4-(3-CHLOROPHENOXY)-3-HYDROXY-1-BUTENYL]-3,5-DIHYDROXY-CYCLOPENTYL)-5-HEPTENOIC ACID SODIUM SALT (5Z)-REL-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-CHLOROPHENOXY)-3-HYDROXY-1-BUTENYL]-3,5-DIHYDROXYCYCLOPENTYL]-5-HEPTENOIC ACID MONOSODIUM SALT CLOPROSTENOL NA (+)-CLOPROSTENOL SODIUM SALT (+/-)-CLOPROSTENOL SODIUM SALT CLOPROSTENOL SODIUM SALT (+)-Cloprostenol Sodium (Subject to Patent Free) sodium [1alpha(Z),2beta(1E,3R*),3alpha,5alpha]-(±)-7-[2-[4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate (+/-)-CLOPROSTENOL SODIUM SALT HYDRATE CloprostadilSodium 5-Heptenoic acid, 7-(1R,2R,3R,5S)-2-(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl-3,5-dihydroxycyclopentyl-, monosodium salt, (5Z)-rel- Sodium [1alpha(Z),2beta(1E,3R*),3alpha,5alpha]-(+/-)-7-[2-[4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3S)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Sodium Salt Ciosin Estrumat Planate sodium(Z)-7-(2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en- Sodium chlorprostaglandin ICI 80996 sodium salt (±)-Cloprostenol sodium salt USP/EP/BP Cloprostenol Sodium (1140666) 16-(3-CHLOROPHENOXY)-9,11,15R-TRIHYDROXY-17,18,19,20-TETRANORPROSTA-5Z,13E-DIEN-1-OIC ACID SODIUM SALT DL-Cloprostenol sodiuM D-Cloprostenol sodiuM CLOPROSTENOL SODIUM sodium(Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate (+/-)-Cloprostenol sodium salt hydrate Sodium (Z)-rel-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, sodium salt (1:1), (5Z)-rel- (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-Heptenoic acid sodium salt (1:1) Cloprostenol Impurity 5 (DL-Cloprostenol Sodium Salt) Deferoxamine Impurity 2 55028-72-3 55028-50-8 40665-92-7(62561-03- C22H28O6ClNa C22H28ClNaO6 C22H29ClO6 Other APIs Pharmaceuticals