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ChemicalBook >> CAS DataBase List >>2,6,6-Trimethyl-2-cyclohexene-1,4-dione

2,6,6-Trimethyl-2-cyclohexene-1,4-dione

2,6,6-Trimethyl-2-cyclohexene-1,4-dione Structure
2,6,6-Trimethyl-2-cyclohexene-1,4-dione structure
CAS No.
1125-21-9
Chemical Name:
2,6,6-Trimethyl-2-cyclohexene-1,4-dione
Synonyms
KETOISOPHORONE;4-KETOISOPHORONE;4-OXOISOPHORONE;2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE;FEMA 3421;Oxophorone;OXOISOPHORONE;4-OXOISOPHORON;2,2,6-trimethyl-2-cyclohexene-1,4-dione (cetoisophorone);Oxopholone
CBNumber:
CB7701362
Molecular Formula:
C9H12O2
Molecular Weight:
152.19
MDL Number:
MFCD00043119
MOL File:
1125-21-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-24 21:23:22
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2,6,6-Trimethyl-2-cyclohexene-1,4-dione Properties

Melting point 26-28 °C (lit.)
Boiling point 222 °C (lit.) 92-94 °C/11 mmHg (lit.)
Density 1.03
refractive index n20/D 1.491(lit.)
FEMA 3421 | 2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE
FLAVIS Number 07.109 | 2,6,6-Trimethylcyclohex-2-en-1,4-dione
Flash point 201 °F
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Liquid
color Pale Yellow to Yellow
Odor at 1.00 % in dipropylene glycol. musty woody sweet tea tobacco leaf
Odor Type musty
biological source synthetic
JECFA Number 1857
BRN 2207030
Major Application flavors and fragrances
Cosmetics Ingredients Functions PERFUMING
InChI 1S/C9H12O2/c1-6-4-7(10)5-9(2,3)8(6)11/h4H,5H2,1-3H3
InChIKey AYJXHIDNNLJQDT-UHFFFAOYSA-N
SMILES CC1=CC(=O)CC(C)(C)C1=O
LogP 0.76
CAS DataBase Reference 1125-21-9(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE
FDA UNII 72WY3KLB5R
NIST Chemistry Reference 2,6,6-Trimethyl-2-cyclohexene-1,4-dione(1125-21-9)
EPA Substance Registry System 2-Cyclohexene-1,4-dione, 2,6,6-trimethyl- (1125-21-9)
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P280-P302+P352
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-43-36/37/38
Safety Statements  26-36/37-37/39-24/25
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
TSCA  TSCA listed
HS Code  29142900
Storage Class 11 - Combustible Solids
Hazard Classifications Skin Sens. 1
REACH Registrations Active
NFPA 704
1
2 0

2,6,6-Trimethyl-2-cyclohexene-1,4-dione price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W342106 4-Oxoisophorone ≥98%, FG 1125-21-9 1 each $58 2026-04-30 Buy
Sigma-Aldrich W342106 4-Oxoisophorone ≥98%, FG 1125-21-9 100g $86 2026-04-30 Buy
Sigma-Aldrich W342106 4-Oxoisophorone ≥98%, FG 1125-21-9 1kg $367 2026-04-30 Buy
Sigma-Aldrich W342106 4-Oxoisophorone ≥98%, FG 1125-21-9 5kg $1560 2026-04-30 Buy
Sigma-Aldrich 329517 2,6,6-Trimethyl-2-cyclohexene-1,4-dione 98% 1125-21-9 25g $148 2026-04-30 Buy
Product number Packaging Price Buy
W342106 1 each $58 Buy
W342106 100g $86 Buy
W342106 1kg $367 Buy
W342106 5kg $1560 Buy
329517 25g $148 Buy

2,6,6-Trimethyl-2-cyclohexene-1,4-dione Chemical Properties, Uses, Production

Chemical Properties

2,6,6,-Trimethylcyclohex-2-ene-1,4-dione has a woody, musty sweet aroma.

Chemical Properties

clear yellow to orange liquid or low melting solid

Occurrence

Reported found among the volatile components in saffron and in cigarette smoke. Also reported found in saffron, cognac, black tea, green tea, microbial fermented tea, lemon balm, cooked shrimp, roasted shrimp, corn oil and lamb’s lettuce.

Uses

4-Oxoisophorone is one of the major components of saffron (Crocus sativus L.) and also found to be a product of degradation of carotenoids in paprika, tomato and marigold oleoresins.

Definition

ChEBI: 2,6,6-Trimethyl-2-cyclohexene-1,4-dione is a member of cyclohexenones.

General Description

2,6,6-Trimethyl-2-cyclohexene-1,4-dione is also known as 4-ketoisophorone and is the major component of saffron spice. It is a cyclic olefin and was reported as a product of the thermal degradation of β-carotene in aqueous suspension.

2,6,6-Trimethyl-2-cyclohexene-1,4-dione Preparation Products And Raw materials

Raw materials

Preparation Products

Isophorone oxide

2,6,6-Trimethyl-2-cyclohexene-1,4-dione Suppliers

Global Suppliers ( 365)
Supplier Tel Email Country ProdList Advantage
Taizhou Jiecheng Chemical Co., Ltd. 0576-88203651 15967007102 103858443@qq.com China 270 58
Hubei Langbowan Biopharmaceutical Co., Ltd  18086032675 3831791620@qq.com China 1798 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Accela ChemBio Co.,Ltd. 4000665055 marketing@accelachem.com China 10972 64
jiliang chemicals 21-62165282 bidingchem@163.com China 1395 60
Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3294 57
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Supplier Advantage
Taizhou Jiecheng Chemical Co., Ltd. 58
Hubei Langbowan Biopharmaceutical Co., Ltd  58
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Accela ChemBio Co.,Ltd. 64
jiliang chemicals 60
Beijing Isomersyn Technology CO;LTD 57
Shandong Xiya Chemical Co., Ltd 57

View Latest Price from 2,6,6-Trimethyl-2-cyclohexene-1,4-dione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,6,6-Trimethyl-2-cyclohexene-1,4-dione pictures 2026-10-08 2,6,6-Trimethyl-2-cyclohexene-1,4-dione
1125-21-9
 $100.00 1KG 99% 1000 KG HANGZHOU DINGYAN CHEM CO.,LTD
2,6,6-Trimethyl-2-cyclohexene-1,4-dione pictures 2026-06-30 2,6,6-Trimethyl-2-cyclohexene-1,4-dione
1125-21-9
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2,6,6-Trimethyl-2-cyclohexene-1,4-dione pictures 2026-03-20 2,6,6-Trimethyl-2-cyclohexene-1,4-dione
1125-21-9
 $10.00 1KG 99% 5tons Hebei Chuanghai Biotechnology Co., Ltd

2,6,6-Trimethyl-2-cyclohexene-1,4-dione Spectrum

2,6,6-Trimethyl-2-cyclohexene-1,4-dione(1125-21-9)1HNMR2,6,6-Trimethyl-2-cyclohexene-1,4-dione(1125-21-9)IR2,6,6-Trimethyl-2-cyclohexene-1,4-dione(1125-21-9)Raman

1125-21-9 (2,6,6-Trimethyl-2-cyclohexene-1,4-dione) Related Search:

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2-Ethylfenchol 2,5-Heptanedione 2-Methyl-2-cyclohexen-1-one 2-Cyclohexene-1,4-dione 2,6,6-Trimethyl-2-cyclohexene-1,4-dione
2-Methoxy-3,5,5-trimethyl-2-cyclohexene-1,4-dione (6E)-6-(2H-1-Benzopyran-2-ylidene)-5-methoxy-2,2,4-trimethyl-4-cyclohexene-1,3-dione

1of4

2,6,6-Trimethy-2-cyclohexene-1,4-dione (4-oxoisophorone) 4-dione,2,6,6-trimethyl-2-Cyclohexene-1 2-ETHYLFENCHOL 97+% FCC 2,6,6-Trimethyl-2-cyclohexe 4-ketoisophotone 2,6,6-TRIMETHYL-2-CYCLOHEXENE-1,4-DIONE 98+% 2,6,6-TRIMETHYL-2-CYCLOHEXEN-1,4-DIONE 2,6,6-TRIMETHYL-2-CYCLOHEXENE-1,4-DIONE 2,6,6-Trimethyl-2-cyclohexene-1,4-dione, 4-Oxoisophorone, Ketoisophorone 2,6,6-trimethyl-2-cyclohexene-4-dione 2,6,6-trimethylcyclohex- 4-Oxoisophorone, Ketoisophorone 6-Oxoisophorone 2,6,6-TriMethyl-2-cyclohexene-1,4-dione 98% 4-Oxoisophorone 2,6,6-Trimethyl-2-cyclohexen-1,4-dione 2,6,6-TriMethyl-2-clclohexen-1,4-dione 3,5,5-TriMethyl-2-clclohexen-1,4-dione 2,6,6-trimethylcyclohex-2-ene 2-Cyclohexen-1,4-dione, 2,6,6-trimethyl 2-Cyclohexene-1,4-dione, 2,6,6-trimethyl- 3,5,5-trimethyl-2-cyclohexene-1,4-dione 3,5,5-trimethylcyclohex-2-ene-1,4-dione 6-Trimethyl-2-cyclohexene-1 4-Ketoisophorone> 2,6,6-Trimethyl-2-cyclohexene-1,4-dione USP/EP/BP TIANFU-CHEM -2,6,6-Trimethyl-2-cyclohexene-1,4-dione 2,2,6-trimethyl-2-cyclohexene-1,4-dione (cetoisophorone) 2,2,6-trimethylcyclohex-2-en-1,4-dione (4-oxo-isophorone) OXOISOPHORONE Oxopholone 3,5,5-Trimethylcyclohex-2-en-1,4-dione 2,6,6-Trimethyl-2-cyclohexene Ketone isophorone Tea Flavone Venlafaxine Impurity 1 Hydrochloride（Venlafaxine EP Impurity A Hydrochloride） Ketoisophorone, 10 mM in DMSO 3,5,5-Trimethyl-2-cyclohexen-1,4-dione Dihydroterpineol(95%,97%andabove) Tea aroma ketone Theaketone 2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE 2,6,6-Trimethylcycohex-2-ene-1,4-dione 4-KETOISOPHORONE 4-OXOISOPHORON 4-OXOISOPHORONE FEMA 3421 KETOISOPHORONE Oxophorone 2,6,6-Trimethyl-2-cyclohexene-1,4-dione (Ketoisophorone) 1125-21-9 5-21-9 Ketones Organic Building Blocks C9 Carbonyl Compounds Building Blocks Inhibitors ketone Flavor