11BETA-PROSTAGLANDIN E1
- CAS No.
- 27415-26-5
- Chemical Name:
- 11BETA-PROSTAGLANDIN E1
- Synonyms
- 8-epi-PGF2α;(5Z,8β,9α,11α,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic Acid;15-F2t-IsoP;8-Iso-PGF2α;8-ISOPROSTANE;IPF2ALPHA-III;15-F2t-IsoP-d9;8-epi-PGF2α-d9;8-Iso-PGF2α-d9;8-EPI PGF2ALPHA
- CBNumber:
- CB7701867
- Molecular Formula:
- C20H34O5
- Molecular Weight:
- 354.48
- MDL Number:
- MFCD00084822
- MOL File:
- 27415-26-5.mol
| Boiling point | 531.0±50.0 °C(Predicted) |
|---|---|
| Density | 1.153±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: 3 mg/ml |
| form | A crystalline solid |
| pka | 4.76±0.10(Predicted) |
| FDA UNII | W83YE66SBY |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H360 | |||||||||
| Precautionary statements | P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501 | |||||||||
| NFPA 704 |
|
11BETA-PROSTAGLANDIN E1 price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16350 | 8-iso Prostaglandin F2α ≥99% | 27415-26-5 | 1mg | $164 | 2024-03-01 | Buy |
| Cayman Chemical | 16350 | 8-iso Prostaglandin F2α ≥99% | 27415-26-5 | 5mg | $692 | 2024-03-01 | Buy |
| Cayman Chemical | 25903 | 8-iso Prostaglandin F2α MaxSpec® Standard | 27415-26-5 | 100μg | $214 | 2024-03-01 | Buy |
| Cayman Chemical | 16350 | 8-iso Prostaglandin F2α ≥99% | 27415-26-5 | 10mg | $1221 | 2024-03-01 | Buy |
| TRC | P838620 | 8-epi-ProstaglandinF2α | 27415-26-5 | 10mg | $10725 | 2021-12-16 | Buy |
11BETA-PROSTAGLANDIN E1 Chemical Properties,Uses,Production
Description
8-iso PGF2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2α level of about 150 pg/ml in normal volunteers. In normal human urine, 8-iso PGF2α levels are about 180-200 pg/mg of creatinine. 8-iso PGF2α is a weak TP receptor agonist in vascular smooth muscle. Conversely, 8-iso PGF2α inhibits platelet aggregation induced by U-
Description
8-iso Prostaglandin F2α (8-iso PGF2α) is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2α level of about 150 pg/ml in normal volunteers. In normal human urine, 8-iso PGF2α levels are about 180-200 pg/mg of creatinine. 8-iso PGF2α is a weak TP receptor agonist in vascular smooth muscle. Conversely, 8-iso PGF2α inhibits platelet aggregation induced by U-
8-iso Prostaglandin F2α MaxSpec® standard is a quantitative grade standard of 8-
Uses
(8-epi-prostaglandin F2a) A major metabolite of PGF2α. A prostaglandin derivative used as a biomarker in the diagnosis and treatment of cardiovascular-related diseases as well as biomarkers of total body oxidative stress.
Uses
A major metabolite of PGF2α. A prostaglandin derivative used as a biomarker in the diagnosis and treatment of cardiovascular-related diseases as well as biomarkers of total body oxidative stress.
Definition
ChEBI: A prostanoid that is prostaglandin F2alpha having inverted stereochemistry at the 8-position.
11BETA-PROSTAGLANDIN E1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9911 | 50 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 | synstar518@163.com | China | 1991 | 58 |