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Triethyl orthoacetate

CAS No.
78-39-7
Chemical Name:
Triethyl orthoacetate
Synonyms
TEOA;1,1,1-TRIETHOXYETHANE;Ethane, 1,1,1-triethoxy-;ETHYL ORTHOACETATE;TRIETHYL-O-ACETATE;Triethylorthoacetat;triethyl ester orthoacetic acid;ETHYL O-ACETATE;Triethyl proacetate;TRIETHYL ORTHACETATE
CBNumber:
CB7702576
Molecular Formula:
C8H18O3
Molecular Weight:
162.23
MDL Number:
MFCD00009223
MOL File:
78-39-7.mol
MSDS File:
SDS
Last updated:2024-04-12 23:00:59

Triethyl orthoacetate Properties

Boiling point 142 °C (lit.)
Density 0.885 g/mL at 25 °C (lit.)
vapor pressure 3.4 hPa (20 °C)
refractive index n20/D 1.396(lit.)
RTECS KJ4075000
Flash point 97 °F
storage temp. Store below +30°C.
solubility soluble in Chloroform, Ethyl Acetate
form Liquid
color Clear colorless to slightly yellow
explosive limit 0.9-7.0%(V)
Water Solubility SLIGHTLY SOLUBLE
Sensitive Moisture Sensitive
BRN 506201
LogP 2.6 at 20℃
CAS DataBase Reference 78-39-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 48352MHC78
NIST Chemistry Reference Ethane, 1,1,1-triethoxy-(78-39-7)
EPA Substance Registry System Ethane, 1,1,1-triethoxy- (78-39-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Warning
Hazard statements  H226
Precautionary statements  P210
Hazard Codes  Xi
Risk Statements  10-36/38
Safety Statements  26-37/39-16
RIDADR  UN 3272 3/PG 3
WGK Germany  1
Autoignition Temperature 455 °C
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29159080
NFPA 704
3
2 2

Triethyl orthoacetate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20934 Triethyl orthoacetate for synthesis 78-39-7 50mL $28.6 2024-03-01 Buy
Sigma-Aldrich 8.20934 Triethyl orthoacetate for synthesis 78-39-7 100mL $35.9 2024-03-01 Buy
Sigma-Aldrich 8.20934 Triethyl orthoacetate for synthesis 78-39-7 500mL $73.2 2024-03-01 Buy
Sigma-Aldrich 75580 Triethyl orthoacetate purum, ≥98.0% (GC) 78-39-7 100ml $45.6 2024-03-01 Buy
Sigma-Aldrich 75580 Triethyl orthoacetate purum, ≥98.0% (GC) 78-39-7 500ml $125 2024-03-01 Buy
Product number Packaging Price Buy
8.20934 50mL $28.6 Buy
8.20934 100mL $35.9 Buy
8.20934 500mL $73.2 Buy
75580 100ml $45.6 Buy
75580 500ml $125 Buy

Triethyl orthoacetate Chemical Properties,Uses,Production

Description

Triethyl orthoacetate is the ethyl orthoester of acetic acid. It is an oily liquid with a pungent odor. Triethyl orthoacetate is used as a water scavenger and as intermediate for synthesis of pharmaceuticals. It is used in organic synthesis for the introduction of the acetate group to an alcohol and in the Johnson-Claisen rearrangement.

Reference

  • J. S. Lindsey, I. C. Schreiman, H. C. Hsu, P. C. Kearney, A. M. Marguerettaz, Rothemund and Adler-Longo reactions revisited: synthesis of tetraphenylporphyrins under equilibrium conditions, The Journal of Organic Chemistry, 1987, vol. 52, pp. 827-836
  • R. C. Capozza, Polymeric orthoesters housing beneficial drug for controlled release therefrom, Patent US4066747A

Chemical Properties

clear colourless liquid

Uses

Intermediate.

Uses

Triethyl orthoacetate is used as pharmaceutical and water scavenger. It is also used in organic synthesis to introduce the acetate group into an alcohol. It is involved in the Johnson-Claisen rearrangement.

Hazard

Moderate fire risk.

Flammability and Explosibility

Flammable

60-29-7
141-78-6
78-39-7
Synthesis of Triethyl orthoacetate from Diethyl ether and Ethyl acetate
Global( 400)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Believe Chemical PTE.LTD
+86-18553607090 +8618553607090 1093908296@qq.com China 1684 58
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Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7613 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+86-13474506593 +86-13474506593 sarah@tnjone.com China 864 58
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13867897135 sales@nbinno.com CHINA 925 58
Hubei Jusheng Technology Co.,Ltd.
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View Lastest Price from Triethyl orthoacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
 Triethyl Orthoacetate pictures 2024-04-12 Triethyl Orthoacetate
78-39-7
US $0.00 / kg 1kg 99% 10000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
Triethyl orthoacetate pictures 2024-03-23 Triethyl orthoacetate
78-39-7
US $31.00-1.20 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Triethyl orthoacetate pictures 2023-10-30 Triethyl orthoacetate
78-39-7
US $10.00 / kg 1kg 99% 20 tons Shandong Believe Chemical PTE.LTD
Ethyl Orthoacetate 1,1,1-Triethoxyethane Orthoacetic Acid Triethyl Ester The originalacetic acidethyl ester three The original three ethyl acetate 1,1′,1′′-(Ethylidynetris[oxy])-tris(ethane) Triethyl orthoacetate purum, >=98.0% (GC) Triethyl orthoacetate(TEOA) 1,1,1-triethoxy-ethan LABOTEST-BB LT00067780 TRIETHYL ORTHACETATE TRIETHYL ORTHOACETATE TRIETHYL-ORTHO ACETOACETATE Triethylorthoacetate,98% Triethyl Orthoacetate-1,2-13C2 Triethyl orthoacetate, 97% 100ML Triethyl orthoacetate, 97% 2.5LT Triethyl orthoacetate, 97% 500ML ORTHOACETIC ACID TRIETHYL ESTER ETHYL O-ACETATE Methylorthoformic acid triethyl ester Orthoacetic acid triethyl Triethyl orthoacetate,99% Triethyl orthoacetate,97% Triethyl orthoacetate ,98.5% TRIETHYL ORTHOACETATETRIETHYL ORTHOACETATE TriethylOrthoacetate> Triethyl proacetate 1,1,1-TRIETHOXYETHANE ETHYL ORTHOACETATE TRIETHYL-O-ACETATE Triethylorthoacetat triethyl ester orthoacetic acid Ethane, 1,1,1-triethoxy- TEOA Valproic Acid Impurity 97 78-39-7 CH3COC2H53 CH3COCH2CH33 Orthoesters Building Blocks Oxygen Compounds Organic Building Blocks Acetals/Ketals/Ortho Esters Intermediates of Dyes and Pigments Orthoesters Acetals/Ketals/Ortho Esters Building Blocks Chemical Synthesis Organic Building Blocks Oxygen Compounds