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5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE structure

CAS No.: 65156-94-7

Chemical Name:: 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE

Synonyms: 5-Chloro-4-azaindole;5-cChloro-1H-pyrrolo[3,2-b]pyridine;5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE;1H-Pyrrolo[3,2-b]pyridine, 5-chloro-;5-Chloro-4-azaindole,5-chloro-1H-pyrrolo[3,2-b]pyridine

CBNumber:: CB7704671

Molecular Formula:: C7H5ClN2

Molecular Weight:: 152.58

MDL Number:: MFCD08062553

MOL File:: 65156-94-7.mol

Last updated:2025-07-24 18:13:46

Product description	Number	Pack Size	Price
5-Chloro-1H-pyrrolo[3,2-b]pyridine Aldrich	ADE000995	1g	$427
5-cChloro-1H-pyrrolo[3,2-b]pyridine	B418638	50mg	$45
5-Chloro-1H-pyrrolo[3,2-b]pyridine	FC38532	250mg	$100
5-Chloro-1H-pyrrolo[3,2-b]pyridine	FC38532	500mg	$160
5-Chloro-1H-pyrrolo[3,2-b]pyridine	026287	500mg	$198
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5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Properties

Boiling point	304.9±22.0 °C(Predicted)
Density	1.425±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	solid
pka	13.75±0.40(Predicted)
Appearance	Light brown to yellow Solid
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05,GHS07
Signal word	Danger
Hazard statements	H302-H318
Precautionary statements	P280-P301+P312+P330-P305+P351+P338+P310
Hazard Codes	Xi
WGK Germany	3
HazardClass	IRRITANT
HS Code	2933998090

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE000995	5-Chloro-1H-pyrrolo[3,2-b]pyridine Aldrich	65156-94-7	1g	$427	2025-07-31	Buy
TRC	B418638	5-cChloro-1H-pyrrolo[3,2-b]pyridine	65156-94-7	50mg	$45	2021-12-16	Buy
Biosynth Carbosynth	FC38532	5-Chloro-1H-pyrrolo[3,2-b]pyridine	65156-94-7	250mg	$100	2021-12-16	Buy
Biosynth Carbosynth	FC38532	5-Chloro-1H-pyrrolo[3,2-b]pyridine	65156-94-7	500mg	$160	2021-12-16	Buy
Matrix Scientific	026287	5-Chloro-1H-pyrrolo[3,2-b]pyridine	65156-94-7	500mg	$198	2021-12-16	Buy

Product number	Packaging	Price	Buy
ADE000995	1g	$427	Buy
B418638	50mg	$45	Buy
FC38532	250mg	$100	Buy
FC38532	500mg	$160	Buy
026287	500mg	$198	Buy

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Chemical Properties,Uses,Production

Uses

5-Chloro-1H-pyrrolo[3,2-B]pyridine can be used as an organic synthesis intermediate and a pharmaceutical intermediate, and is mainly used in laboratory research and development processes and chemical pharmaceutical production processes.

Synthesis

3-Pyridinamine, 6-chloro-2-[(1E)-2-ethoxyethenyl]-

1420070-26-3

65156-94-7

General procedure for the synthesis of 5-chloro-1H-pyrrolo[3,2-B]pyridine from compound (CAS:1420070-26-3): 5-chloro-1H-pyrrolo[3,2-B]pyridine (1.01 g, 5.1 mmol) was dissolved in 20 mL of methanol. 1 mL of concentrated hydrochloric acid was added and the reaction mixture was stirred at 75 °C for 21 hours. After completion of the reaction, the solvent was removed by evaporation under reduced pressure and the residue was extracted by partitioning with saturated potassium carbonate solution and ethyl acetate. The organic layer was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Purification by fast column chromatography (eluent: ethyl acetate/hexane, 33:67, v/v) afforded 0.55 g (3.6 mmol, 71% yield) of the target product, 5-chloro-1H-pyrrolo[3,2-B]pyridine, as a light yellow solid with 95% purity.1H NMR (300 MHz, CDCl3 + DMSO-d6) δ 9.85 (br. s , 1H), 7.67 (d, J = 8.5 Hz, 1H), 7.47 (m, 1H), 7.10 (d, J = 8.5 Hz, 1H), 6.65 (m, 1H).HPLC/MS analysis (run time 9 min) showed a retention time of 4.27 min. Low resolution mass spectrometry (LRMS): m/z 153 ([M + H]+).

References

[1] Patent: EP2548876, 2013, A1. Location in patent: Paragraph 0283-0286
[2] Patent: WO2013/10880, 2013, A1. Location in patent: Page/Page column 83

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE synthesis

Synthesis of 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE from 3-Pyridinamine, 6-chloro-2-[(1E)-2-ethoxyethenyl]-

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Preparation Products And Raw materials

Raw materials

3-Pyridinamine, 6-chloro-2-[(1E)-2-ethoxyethenyl]- 3-Pyridinamine, 6-chloro-2-[2-(trimethylsilyl)ethynyl]- 1H-Pyrrolo[3,2-b]pyridine, 5-chloro-1-[(4-methylphenyl)sulfonyl]- 5H-Pyrrolo[3,2-b]pyridin-5-one (6-Chloro-3-nitro-pyridin-2-yl)-acetonitrile

2-Bromo-6-chloropyridin-3-amine 3-Amino-2-chloro-6-iodopyridine 5-Amino-2-chloropyridine Methanol Hydrochloric acid

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Preparation Products

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Suppliers

Global( 153)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	+8618795957998	karmelhk@126.com	CHINA	2886	58
Unipharm pharmaceutical industry Co., Ltd	536-8266195 +8613953676784	lee@unipharm-sd.com	China	1202	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9215	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	58
Unipharm pharmaceutical industry Co., Ltd	58
Baoji Guokang Healthchem Co., Ltd.	58

View Lastest Price from 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-07-13	5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 65156-94-7	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10	5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 65156-94-7	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2020-01-13	5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 65156-94-7	US $9.80 / KG	1g	≥99%	100kg	Career Henan Chemical Co

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE
65156-94-7
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE
65156-94-7
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE
65156-94-7
US $9.80 / KG
≥99%
Career Henan Chemical Co

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE Spectrum

5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE(65156-94-7)¹HNMR

65156-94-7(5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE)Related Search:

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5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE 5-Chloro-7-azaindole-3-carboxaldehyde 5-Chloro-7-azaindole-3-carboxylic acid Methyl ester

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5-Chloro-4-azaindole,5-chloro-1H-pyrrolo[3,2-b]pyridine 1H-Pyrrolo[3,2-b]pyridine, 5-chloro- 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 5-Chloro-4-azaindole 5-cChloro-1H-pyrrolo[3,2-b]pyridine 65156-94-7 Azaindoles