(-)-4-BROMOTETRAMISOLE OXALATE
- CAS No.
- 62284-79-1
- Chemical Name:
- (-)-4-BROMOTETRAMISOLE OXALATE
- Synonyms
- (-)-P-BROMOTETRAMISOLE OXALATE;(-)-p-Bromotetramisole oxalate;(S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate;R 30402;6-BROMOLEVAMISOLE OXALATE;L-P-BROMOTETRAMISOLE OXALATE;(-)-P-BROMOLEVAMISOLE OXALATE;(-)-4-BROMOTETRAMISOLE OXALATE;Bromotetramisole, L(-) oxalate;(-)-4-BROMOTETRAMISOLE OXALATE
- CBNumber:
- CB7709111
- Molecular Formula:
- C13H13BrN2O4S
- Molecular Weight:
- 373.22
- MDL Number:
- MFCD00070406
- MOL File:
- 62284-79-1.mol
- MSDS File:
- SDS
| Melting point | 192 °C (dec.) (lit.) |
|---|---|
| Flash point | 87℃ |
| storage temp. | 2-8°C |
| solubility | Soluble in Water (up to 10 mg/ml) |
| form | liquid |
| color | White |
| optical activity | [α]25/D 104°, c = 0.5 in H2O |
| BRN | 4944883 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352+P312-P362+P364 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 21/22-36/37/38-20/21/22 | |||||||||
| Safety Statements | 24/25-36/37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| NFPA 704 |
|
(-)-4-BROMOTETRAMISOLE OXALATE price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 190047 | (?)-p-Bromolevamisole oxalate 99% | 62284-79-1 | 25mg | $68.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 190047 | (?)-p-Bromolevamisole oxalate 99% | 62284-79-1 | 100mg | $462 | 2024-03-01 | Buy |
| Cayman Chemical | 18713 | L-p-Bromotetramisole (oxalate) ≥98% | 62284-79-1 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 18713 | L-p-Bromotetramisole (oxalate) ≥98% | 62284-79-1 | 5mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 18713 | L-p-Bromotetramisole (oxalate) ≥98% | 62284-79-1 | 10mg | $109 | 2024-03-01 | Buy |
(-)-4-BROMOTETRAMISOLE OXALATE Chemical Properties,Uses,Production
Description
Four distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like). L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (Kis =18 and 56 μM for PLAP and NSAP, respectively). While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition. L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.
Chemical Properties
white to light yellow crystal powde
Uses
L-p-Bromotetramisole Oxalate or (-)-p-Bromotetramisole Oxalate is a potent inhibitor of alkaline phosphatase.
Biochem/physiol Actions
(-)-p-Bromolevamisole oxalate inhibits L-isoforms of alkaline phosphatases.
target
alkaline phosphatase
References
1) Kovach?et al. (1992),?Levamisole potentiation of fluorouracil antiproliferative activity mimicked by orthovanadate, an inhibitor of tyrosine phosphatase; J. Natl. Cancer Inst.,?84?515 2) Luo et al. (2000),?Role of protein phosphatases in the activation of CTFR (ABCC7) by genistein and bromotetramisole;?Am. J. Physiol. Cell Physiol.,?279?C108 3) Scher?et al.?(1998),?The phosphatase inhibitors, orthovanadate and levamisole, inhibit induction of erythroid differentiation and abrogate the associated inhibition of glycolysis; Int. J. Oncol.,?12?987
(-)-4-BROMOTETRAMISOLE OXALATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29322 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Zhangshu Hongyuan Biomedical Technology Co., Ltd. | 19195036662 | 335864138@qq.com | China | 159 | 58 |
View Lastest Price from (-)-4-BROMOTETRAMISOLE OXALATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-19 | (-)-4-BROMOTETRAMISOLE OXALATE USP/EP/BP
62284-79-1
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-02-02 | (-)-4-BROMOTETRAMISOLE OXALATE
62284-79-1
|
US $3.00 / KG | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- (-)-4-BROMOTETRAMISOLE OXALATE USP/EP/BP
62284-79-1
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- (-)-4-BROMOTETRAMISOLE OXALATE
62284-79-1
- US $3.00 / KG
- 98%
- Career Henan Chemical Co
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