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EXO1

CAS No.
461681-88-9
Chemical Name:
EXO1
Synonyms
EXO1;EOX 1;hExoI;hExo1;Exo 1,Exo1;Exonuclease 1;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE;Anti-EXO1, N-Terminal antibody produced in rabbit
CBNumber:
CB7713354
Molecular Formula:
C15H12FNO3
Molecular Weight:
273.26
MDL Number:
MFCD00028104
MOL File:
461681-88-9.mol
Last updated:2023-09-04 16:42:00

EXO1 Properties

Melting point 132-134℃
Boiling point 415.2±45.0 °C(Predicted)
Density 1.246±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility DMSO: 19 mg/mL, soluble
form solid
pka -1.09±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P280h-P301+P312a-P304+P340-P321-P501a
WGK Germany  3

EXO1 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J67103 Methyl 2-(4-fluorobenzamido)benzoate, 98% 461681-88-9 10mg $109 2021-12-16 Buy
Tocris 1850 Exo 1 ≥99%(HPLC) 461681-88-9 10 $123 2021-12-16 Buy
Tocris 1850 Exo 1 ≥99%(HPLC) 461681-88-9 50 $515 2021-12-16 Buy
TRC E962510 Exo 1 461681-88-9 1mg $45 2021-12-16 Buy
Usbiological 255279 Exo 1 461681-88-9 10mg $366 2021-12-16 Buy
Product number Packaging Price Buy
J67103 10mg $109 Buy
1850 10 $123 Buy
1850 50 $515 Buy
E962510 1mg $45 Buy
255279 10mg $366 Buy

EXO1 Chemical Properties,Uses,Production

Uses

Exo1 is used in the synthetic preparation of tricyclic heterocyclic compounds as antagonists of tachykinin receptor (substance P receptor) for prevention and/or treatment of substance P-related diseases.

Definition

ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides.

Biological Activity

Reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC 50 ~ 20 mM). Has similar, but not identical, action to brefeldin A (1,6,7,8,9,11ab,12,13,14,14aa-Decahydro-1b,13a-dihydroxy-6b-methyl-4H-cyclopent(f)oxacyclotridecin-4-one ).

EXO1 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 52)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Ascent Scientific 4401179829988 customerservice@ascentscientific.co.uk United Kingdom 279 60
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Xianning Shen Lan Biomedical Research and Development Co., Ltd. 18171815831 1341138380@qq.com China 2625 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 3820 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5754 58

EXO1 Spectrum

EOX 1 EXOCYTIC INHIBITOR 1 EXO1 4-FLUORO-BZ-2-ABZ-OME 2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER 2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE Anti-EXO1, N-Terminal antibody produced in rabbit Exonuclease 1 hExo1 hExoI Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate Exo 1,Exo1 2-Pyridinecarboxylic acid, 3-(4-fluorobenzoyl)-6-methyl-, methyl ester 461681-88-9 C15H12FNO3 Signalling