FORTUNELLIN
- CAS No.
- 20633-93-6
- Chemical Name:
- FORTUNELLIN
- Synonyms
- FORTUNELLIN;ACACETIN-7-NEOHESPERIDOSIDE;ACACETIN-7-O-NEOHESPERIDOSIDE;4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-
- CBNumber:
- CB7713662
- Molecular Formula:
- C28H32O14
- Molecular Weight:
- 592.55
- MDL Number:
- MFCD00063944
- MOL File:
- 20633-93-6.mol
FORTUNELLIN price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | OA71574 | Acacetin-7-neohesperidoside | 20633-93-6 | 5mg | $800 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0029941 | FORTUNELLIN 95.00% | 20633-93-6 | 5MG | $933.82 | 2021-12-16 | Buy |
| Biosynth Carbosynth | OA71574 | Acacetin-7-neohesperidoside | 20633-93-6 | 10mg | $1200 | 2021-12-16 | Buy |
| Biosynth Carbosynth | OA71574 | Acacetin-7-neohesperidoside | 20633-93-6 | 25mg | $2500 | 2021-12-16 | Buy |
| Biosynth Carbosynth | OA71574 | Acacetin-7-neohesperidoside | 20633-93-6 | 1mg | $300 | 2021-12-16 | Buy |
FORTUNELLIN Chemical Properties,Uses,Production
Description
Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation.
Biological Functions
Fortunellin (acacetin 7-O-neohesperidoside) is a citrus flavonoid isolated from kumquat fruit. Kumquat extract has attracted much attention recently for its beneficial effects on human health, which include antitumor, antioxidant and anti-inflammatory characteristics . The beneficial effects of flavonoids on IBD have been confirmed in many studies. However, although fortunellin is the main flavonoid in kumquat, there is a lack of information on its alleviation of IBD.
Mechanism of action
Fortunellin is a citrus flavonoid that is a potential anti-inflammation agent in inflammatory diseases. Fortunellin ameliorated colitis symptoms, including excessive inflammation and oxidative stress. Fortunellin decreased epithelial cell apoptosis through inhibiting PTEN expression in colitis. Fortunellin-induced downregulation of PTEN could be counteracted by miR-374a depletion. Moreover, knockdown of miR-374a in vivo partly inhibited the effects of fortunellin on rat colitis.
FORTUNELLIN Preparation Products And Raw materials
FORTUNELLIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 | market03@meryer.com | China | 40241 | 62 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9664 | 58 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 7059 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 27322 | 60 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8018 | 62 |