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4-Ethyl-2-methoxyphenol

CAS No.
2785-89-9
Chemical Name:
4-Ethyl-2-methoxyphenol
Synonyms
Phenol, 4-ethyl-2-methoxy-;4-ETHYLGUAIACOL;ETHYL GUAIACOL;p-Ethylguaiacol;2-METHOXY-4-ETHYLPHENOL;HOMOVANILLIN;4-Ethylquaiacol;4-Ethyl-2-methoxyphenol (4-ethylguaiacol);Guaiacylethane;FEMA 2436
CBNumber:
CB7723928
Molecular Formula:
C9H12O2
Molecular Weight:
152.19
MDL Number:
MFCD00038714
MOL File:
2785-89-9.mol
MSDS File:
SDS
Last updated:2026-04-10 10:27:28
Product description Number Pack Size Price
4-Ethylguaiacol natural, FG W243615 1 each $66
4-Ethylguaiacol natural, FG W243615 100g $194
4-Ethylguaiacol ≥98%, FCC, FG W243604 1 each $59.8
4-Ethylguaiacol natural, FG W243615 1kg $831
4-Ethylguaiacol ≥98%, FCC, FG W243604 100g $164
More product size

4-Ethyl-2-methoxyphenol Properties

Melting point 15 °C(lit.)
Boiling point 234-236 °C(lit.)
Density 1.063 g/mL at 25 °C(lit.)
FEMA 2436 | 4-ETHYLGUAIACOL
refractive index n20/D 1.528(lit.)
FLAVIS Number 04.008 | 4-Ethylguaiacol
Flash point 226 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 10.31±0.18(Predicted)
form Liquid
Specific Gravity 1.06
color Clear colorless to light yellow
Odor Warm, sweet and spicy-medicinal, very powerful odor
biological source synthetic
Odor Type spicy
JECFA Number 716
BRN 2045329
Henry's Law Constant 5.5×100 mol/(m3Pa) at 25℃, McFall et al. (2020)
Major Application flavors and fragrances
Cosmetics Ingredients Functions PERFUMING
InChI 1S/C9H12O2/c1-3-7-4-5-8(10)9(6-7)11-2/h4-6,10H,3H2,1-2H3
InChIKey CHWNEIVBYREQRF-UHFFFAOYSA-N
SMILES CCc1ccc(O)c(OC)c1
LogP 2.18
CAS DataBase Reference 2785-89-9(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 4-ETHYLGUAIACOL
FDA 21 CFR 172.515
EWG's Food Scores 1
FDA UNII C9NFD83BJ5
NIST Chemistry Reference Phenol, 4-ethyl-2-methoxy-(2785-89-9)
EPA Substance Registry System Phenol, 4-ethyl-2-methoxy- (2785-89-9)
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36-37/39
RIDADR  2810
WGK Germany  2
TSCA  TSCA listed
HazardClass  6.1(b)
PackingGroup  III
HS Code  29071990
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

4-Ethyl-2-methoxyphenol price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W243615 4-Ethylguaiacol natural, FG 2785-89-9 1 each $66 2026-03-19 Buy
Sigma-Aldrich W243615 4-Ethylguaiacol natural, FG 2785-89-9 100g $194 2026-03-19 Buy
Sigma-Aldrich W243604 4-Ethylguaiacol ≥98%, FCC, FG 2785-89-9 1 each $59.8 2026-03-19 Buy
Sigma-Aldrich W243615 4-Ethylguaiacol natural, FG 2785-89-9 1kg $831 2026-03-19 Buy
Sigma-Aldrich W243604 4-Ethylguaiacol ≥98%, FCC, FG 2785-89-9 100g $164 2026-03-19 Buy
Product number Packaging Price Buy
W243615 1 each $66 Buy
W243615 100g $194 Buy
W243604 1 each $59.8 Buy
W243615 1kg $831 Buy
W243604 100g $164 Buy

4-Ethyl-2-methoxyphenol Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow liquid

Chemical Properties

4-Ethylguaiacol has a warm, sweet, spicy, medicinal odor.

Occurrence

Reported found in several distillates of plant origin; it was identified in camphor oil, and it had been reported previously in Tolu and Peru balsam as well as in various wood distillates. Also reported found in cinnamon, coffee, grape, brandy, malt, rum, soy sauce, whiskey, grapefruit juice, smoked fish, lean fish, beer, cognac, cider, grape wines and apple brandy.

Uses

4-Ethyl-2-methoxyphenol is used as smoke flavoring in the food industry and displays antioxidant activity due to its phenolic composition. It is also present in red grapes and in red wines.

Uses

4-Ethylguaiacol is used as smoke flavoring in the food industry and displays antioxidant activity due to its phenolic composition. It is also present in red grapes and in red wines.

Definition

ChEBI: 4-Ethyl-2-methoxyphenol is a member of methoxybenzenes and a member of phenols.

Aroma threshold values

Detection: 25 ppb. Aroma characteristics at 1.0%: slightly sweet, spicy, clove, smoky and phenolic with charred whiskey barrel notes and a slight vanilla-like creaminess.

Taste threshold values

Taste characteristics at 5 to 10 ppm: dry, smoky, clove, phenolic and vanilla-like with tobacco and woody notes, and a burnt bacon oily aftertaste. Taste characteristics at 30 ppm: woody, smoky and spicy with sweet vanilla background.

General Description

4-Ethylguaiacol is a volatile compound, belonging to the class of phenols. It is identified as one of the key aroma components in commercial soy sauce, red wine, and apple cider. The unpleasant smoky, spicy, and clove-like aroma in wine is due to the presence of high concentrations of 4-Ethylguaiacol.

Synthesis

4-Ethyl-2-methoxyphenol is produced from ortho-Dichloro ethylphenol by heating with Ethyl benzyl disulfonic acid and aqueous alkali at 180-200℃, followed by single Methylation.

64080-15-5
124-41-4
2785-89-9
Synthesis of 4-Ethyl-2-methoxyphenol from 2-BROMO-4-ETHYLPHENOL and Sodium Methoxide
Global( 450)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365 mina@chuanghaibio.com China 18126 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3692 58
JINING XINHE CHEMICAL CO., LTD
+8615318402391 sales@xinhepharma.com China 809 58
Sinoway Industrial co., ltd.
+86-0592-5800732 +86-13806035118 xie@china-sinoway.com China 1369 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21592 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29821 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58

View Lastest Price from 4-Ethyl-2-methoxyphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Natural 4-Ethyguaiacol pictures 2026-04-14 Natural 4-Ethyguaiacol
2785-89-9
US $0.00-0.00 / kg 1kg 99% 20tons Sinoway Industrial co., ltd.
4-Ethyl-2-methoxyphenol pictures 2025-12-01 4-Ethyl-2-methoxyphenol
2785-89-9
US $0.00-0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-Ethyl-2-methoxyphenol pictures 2025-09-25 4-Ethyl-2-methoxyphenol
2785-89-9
US $50.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-ethvlguaiacol 4-ethyl guiacol 4-ETHYL-2-METHOXYPHENOL FEMA 2436 4-ETHYLGUAIACOL 98+% FCC 4-ethylguaiacol,1-hydroxy-2-methoxy-4-ethyl-benzene,4-ethyl-2-methoxyphenol 4-Ethylguajakol ETHYLGUAJACOL-4 4-ETHYL GUAIACOL FEMA NO.2436 4-Ethyl-2-methoxyphenol,98% 4-Ethyl-guaiacol >=98.0% 4-Ethyl-2-Methoxyphenol, 98% 5GR 4-Ethylguaiacol 4-Ethyl-2-methoxyphenol 4-ethyl-2-methoxy-pheno 4-Ethyl-2-metoxy phenol 4-Hydroxy-3-methoxy ethylbenzene Phenol, 2-methoxy-4-ethyl TIMTEC-BB SBB008068 1-HYDROXY-2-METHOXY-4-ETHYL BENZENE 4-Ethyl guaiacol(naural) NSC 82313 4-Ethylguajacol 2-Methoxy-4-ethylphenol> 4-Ethyl-2-methoxyphenol USP/EP/BP 4-Ethyl-2-methoxyphenol 2785-89-9 4-ETHYLGUAIACOL ETHYL GUAIACOL HOMOVANILLIN Phenol, 4-ethyl-2-methoxy- Guaiacylethane 4-Ethyl-2-methoxyphenol (4-ethylguaiacol) 4-Ethylquaiacol p-Ethylguaiacol 2-METHOXY-4-ETHYLPHENOL Kynurenine Impurity 1 (N-Formyl Kynurenine) Natural 4-Ethyguaiacol 4-Ethylguaiacol 1000 μg/mL in Methanol 2785-89-9 2785-80-9 785-89-9 1848-09-0 HOCH3OC6H3CH2CHO C2H5C6H32OCH3OH Alphabetical Listings E-F Flavors and Fragrances phenol Flavor Aromatic Phenols Phenoles and thiophenoles Pharmaceutical Raw Materials