4-Ethyl-2-methoxyphenol
- CAS No.
- 2785-89-9
- Chemical Name:
- 4-Ethyl-2-methoxyphenol
- Synonyms
- Phenol, 4-ethyl-2-methoxy-;4-ETHYLGUAIACOL;ETHYL GUAIACOL;p-Ethylguaiacol;2-METHOXY-4-ETHYLPHENOL;HOMOVANILLIN;4-Ethylquaiacol;4-Ethyl-2-methoxyphenol (4-ethylguaiacol);Guaiacylethane;FEMA 2436
- CBNumber:
- CB7723928
- Molecular Formula:
- C9H12O2
- Molecular Weight:
- 152.19
- MDL Number:
- MFCD00038714
- MOL File:
- 2785-89-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Ethylguaiacol natural, FG | W243615 | 1 each | $66 |
| 4-Ethylguaiacol natural, FG | W243615 | 100g | $194 |
| 4-Ethylguaiacol ≥98%, FCC, FG | W243604 | 1 each | $59.8 |
| 4-Ethylguaiacol natural, FG | W243615 | 1kg | $831 |
| 4-Ethylguaiacol ≥98%, FCC, FG | W243604 | 100g | $164 |
| More product size | |||
| Melting point | 15 °C(lit.) |
|---|---|
| Boiling point | 234-236 °C(lit.) |
| Density | 1.063 g/mL at 25 °C(lit.) |
| FEMA | 2436 | 4-ETHYLGUAIACOL |
| refractive index |
n |
| FLAVIS Number | 04.008 | 4-Ethylguaiacol |
| Flash point | 226 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 10.31±0.18(Predicted) |
| form | Liquid |
| Specific Gravity | 1.06 |
| color | Clear colorless to light yellow |
| Odor | Warm, sweet and spicy-medicinal, very powerful odor |
| biological source | synthetic |
| Odor Type | spicy |
| JECFA Number | 716 |
| BRN | 2045329 |
| Henry's Law Constant | 5.5×100 mol/(m3Pa) at 25℃, McFall et al. (2020) |
| Major Application | flavors and fragrances |
| Cosmetics Ingredients Functions | PERFUMING |
| InChI | 1S/C9H12O2/c1-3-7-4-5-8(10)9(6-7)11-2/h4-6,10H,3H2,1-2H3 |
| InChIKey | CHWNEIVBYREQRF-UHFFFAOYSA-N |
| SMILES | CCc1ccc(O)c(OC)c1 |
| LogP | 2.18 |
| CAS DataBase Reference | 2785-89-9(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | 4-ETHYLGUAIACOL |
| FDA 21 CFR | 172.515 |
| EWG's Food Scores | 1 |
| FDA UNII | C9NFD83BJ5 |
| NIST Chemistry Reference | Phenol, 4-ethyl-2-methoxy-(2785-89-9) |
| EPA Substance Registry System | Phenol, 4-ethyl-2-methoxy- (2785-89-9) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 2 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29071990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Ethyl-2-methoxyphenol price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W243615 | 4-Ethylguaiacol natural, FG | 2785-89-9 | 1 each | $66 | 2026-03-19 | Buy |
| Sigma-Aldrich | W243615 | 4-Ethylguaiacol natural, FG | 2785-89-9 | 100g | $194 | 2026-03-19 | Buy |
| Sigma-Aldrich | W243604 | 4-Ethylguaiacol ≥98%, FCC, FG | 2785-89-9 | 1 each | $59.8 | 2026-03-19 | Buy |
| Sigma-Aldrich | W243615 | 4-Ethylguaiacol natural, FG | 2785-89-9 | 1kg | $831 | 2026-03-19 | Buy |
| Sigma-Aldrich | W243604 | 4-Ethylguaiacol ≥98%, FCC, FG | 2785-89-9 | 100g | $164 | 2026-03-19 | Buy |
4-Ethyl-2-methoxyphenol Chemical Properties,Uses,Production
Chemical Properties
clear colorless to light yellow liquid
Chemical Properties
4-Ethylguaiacol has a warm, sweet, spicy, medicinal odor.
Occurrence
Reported found in several distillates of plant origin; it was identified in camphor oil, and it had been reported previously in Tolu and Peru balsam as well as in various wood distillates. Also reported found in cinnamon, coffee, grape, brandy, malt, rum, soy sauce, whiskey, grapefruit juice, smoked fish, lean fish, beer, cognac, cider, grape wines and apple brandy.
Uses
4-Ethyl-2-methoxyphenol is used as smoke flavoring in the food industry and displays antioxidant activity due to its phenolic composition. It is also present in red grapes and in red wines.
Uses
4-Ethylguaiacol is used as smoke flavoring in the food industry and displays antioxidant activity due to its phenolic composition. It is also present in red grapes and in red wines.
Definition
ChEBI: 4-Ethyl-2-methoxyphenol is a member of methoxybenzenes and a member of phenols.
Aroma threshold values
Detection: 25 ppb. Aroma characteristics at 1.0%: slightly sweet, spicy, clove, smoky and phenolic with charred whiskey barrel notes and a slight vanilla-like creaminess.
Taste threshold values
Taste characteristics at 5 to 10 ppm: dry, smoky, clove, phenolic and vanilla-like with tobacco and woody notes, and a burnt bacon oily aftertaste. Taste characteristics at 30 ppm: woody, smoky and spicy with sweet vanilla background.
General Description
4-Ethylguaiacol is a volatile compound, belonging to the class of phenols. It is identified as one of the key aroma components in commercial soy sauce, red wine, and apple cider. The unpleasant smoky, spicy, and clove-like aroma in wine is due to the presence of high concentrations of 4-Ethylguaiacol.
Synthesis
4-Ethyl-2-methoxyphenol is produced from ortho-Dichloro ethylphenol by heating with Ethyl benzyl disulfonic acid and aqueous alkali at 180-200℃, followed by single Methylation.
4-Ethyl-2-methoxyphenol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| JINING XINHE CHEMICAL CO., LTD | +8615318402391 | sales@xinhepharma.com | China | 809 | 58 |
| Sinoway Industrial co., ltd. | +86-0592-5800732 +86-13806035118 | xie@china-sinoway.com | China | 1369 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
View Lastest Price from 4-Ethyl-2-methoxyphenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-14 | Natural 4-Ethyguaiacol
2785-89-9
|
US $0.00-0.00 / kg | 1kg | 99% | 20tons | Sinoway Industrial co., ltd. | |
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2025-12-01 | 4-Ethyl-2-methoxyphenol
2785-89-9
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
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2025-09-25 | 4-Ethyl-2-methoxyphenol
2785-89-9
|
US $50.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-

- Natural 4-Ethyguaiacol
2785-89-9
- US $0.00-0.00 / kg
- 99%
- Sinoway Industrial co., ltd.
-

- 4-Ethyl-2-methoxyphenol
2785-89-9
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- 4-Ethyl-2-methoxyphenol
2785-89-9
- US $50.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd








