FMOC-SER-OME
- CAS No.
- 82911-78-2
- Chemical Name:
- FMOC-SER-OME
- Synonyms
- FMOC-SER-OME;Fmoc-L-Ser-OMe;FMOC-SERINE-OME;Fmoc-Ser-Ome, ≥98%;Tryptophan Impurity 78;Ceftobiprole Impurity 19;FMOC-L-SERINE METHYL ESTER;Fmoc-L-β-hydroxyalanine methyl ester;Fmoc-L-serine methyl ester≥ 99.5% (HPLC);(9H-Fluoren-9-yl)MethOxy]Carbonyl Ser-OMe
- CBNumber:
- CB7736311
- Molecular Formula:
- C19H19NO5
- Molecular Weight:
- 341.36
- MDL Number:
- MFCD00672334
- MOL File:
- 82911-78-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Fmoc-Ser-OMe | F861045 | 250mg | $75 |
| Fmoc-L-serinemethylester | J96847 | 250mg | $15 |
| Fmoc-L-serine methyl ester 97% ee | AS88997 | 1g | $49 |
| Fmoc-L-serinemethylester,99.5%(HPLC) 99.5%(HPLC) | 03925 | 250MG | $56 |
| Fmoc-L-serinemethylester,≥99.5%(HPLC) ≥99.5%(HPLC) | 03925 | 1G | $110.66 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
FMOC-SER-OME price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | F861045 | Fmoc-Ser-OMe | 82911-78-2 | 250mg | $75 | 2021-12-16 | Buy |
| AK Scientific | J96847 | Fmoc-L-serinemethylester | 82911-78-2 | 250mg | $15 | 2021-12-16 | Buy |
| Activate Scientific | AS88997 | Fmoc-L-serine methyl ester 97% ee | 82911-78-2 | 1g | $49 | 2021-12-16 | Buy |
| Chem-Impex | 03925 | Fmoc-L-serinemethylester,99.5%(HPLC) 99.5%(HPLC) | 82911-78-2 | 250MG | $56 | 2021-12-16 | Buy |
| Chem-Impex | 03925 | Fmoc-L-serinemethylester,≥99.5%(HPLC) ≥99.5%(HPLC) | 82911-78-2 | 1G | $110.66 | 2021-12-16 | Buy |
FMOC-SER-OME Chemical Properties,Uses,Production
Chemical Properties
White to off-white powder
Uses
Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor[1][2].
Synthesis
5680-80-8
82911-69-1
82911-78-2
GENERAL STEPS: To a mixed solution of 1,4-dioxane (15 mL) and water (90 mL) containing L-serine methyl ester hydrochloride (10.0 g, 64.3 mmol), sodium bicarbonate (10.8 g, 129 mmol) was added. The reaction mixture was stirred at room temperature for 15 minutes. Subsequently, a solution of 1,4-dioxane (60 mL) of 2,5-dioxopyrrolidin-1-yl 9H-fluoren-9-ylmethyl carbonate (21.7 g, 64.3 mmol) was slowly added to the reaction system, and stirring was continued at room temperature for 14 hours. Upon completion of the reaction, water was added to the reaction mixture and extracted three times with ethyl acetate. The organic layers were combined and washed sequentially with water and saturated brine. The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Ether and heptane were added to the residue and the precipitate was collected by filtration to give fmoc-L-serine methyl ester (22.3 g, yield: quantitative). The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 2.00-2.15 (1H, m), 3.81 (3H, s), 3.89-4.07 (2H, m), 4.20-4.28 (1H, m), 4.39-4.53 (3H, m), 5.63-5.74 (1H, m), 7.29-7.37 (2H , m), 7.38-7.46 (2H, m), 7.55-7.65 (2H, m), 7.74-7.82 (2H, m).
References
[1] Tamiaki H, et al. Synthesis of chlorophyll-amino acid conjugates as models for modification of proteins with chromo/fluorophores. Bioorg Med Chem. 2014 Feb 15;22(4):1421-8. DOI:10.1016/j.bmc.2013.12.059
[2] K?rkk?inen TS, et al. Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides. Carbohydr Res. 2008 Jul 21;343(10-11):1830-4. DOI:10.1016/j.carres.2008.03.034
FMOC-SER-OME Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 | sales@thbiochem.com | CHINA | 305 | 60 |
| GenicBio Limited | +86-21-37621270 | service@genicbio.com | CHINA | 991 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Nanjing Fred Technology Co., Ltd. | +86-02584696168 15380713688 | Austin@fredchem.cn | CHINA | 865 | 58 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
View Lastest Price from FMOC-SER-OME manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | FMOC-SER-OME
82911-78-2
|
US $1.00 / KG | 1KG | 98% | 20kg | Career Henan Chemical Co |
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- FMOC-SER-OME
82911-78-2
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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