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3-Chlorophenol

CAS No.
108-43-0
Chemical Name:
3-Chlorophenol
Synonyms
M-CHLOROPHENOL;3-Chlorphenol;MONOCHLOROPHENOL;NSC 59700;3-Cl-phenol;3-chloro-pheno;m-chloro-pheno;3-CHLOROPHENOL;Phenol,3-chloro-;CHLOROPHENOL(M-)
CBNumber:
CB7740938
Molecular Formula:
C6H5ClO
Molecular Weight:
128.56
MDL Number:
MFCD00002256
MOL File:
108-43-0.mol
MSDS File:
SDS
Last updated:2023-08-11 16:54:45

3-Chlorophenol Properties

Melting point 31-34 °C (lit.)
Boiling point 214 °C (lit.)
Density 1.218 g/mL at 25 °C (lit.)
vapor pressure 1 hPa (44 °C)
refractive index n20/D 1.563(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility Soluble in ethanol and ether.
pka 8.85(at 25℃)
form Liquid After Melting
color Clear yellow to brownish
PH 3.5 (27.7g/l, H2O, 20℃)
Odor distinct phenol-like odor
Relative density, gas (air=1) 1.218 g/cm3 at 25 °C
Water Solubility 27.7 g/L (20 ºC)
Merck 14,2154
BRN 1634401
Stability Stable. Combustible. Incompatible with acid chlorides, oxidizing agents, acid anhydrides. Discolours in air.
CAS DataBase Reference 108-43-0(CAS DataBase Reference)
FDA UNII Z2Z7M2FTAD
NIST Chemistry Reference Phenol, 3-chloro-(108-43-0)
EPA Substance Registry System m-Chlorophenol (108-43-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302+H312+H332-H315-H318-H411
Precautionary statements  P273-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn,N
Risk Statements  20/21/22-51/53
Safety Statements  28-61-28A
RIDADR  UN 2020 6.1/PG 3
WGK Germany  2
RTECS  SK2450000
9
Autoignition Temperature >600 °C
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29081000
Toxicity LD50 orally in rats: 0.57 g/kg (Deichmann)
NFPA 704
1
2 0

3-Chlorophenol price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C62808 3-Chlorophenol 98% 108-43-0 100g $40.56 2024-03-01 Buy
Sigma-Aldrich C62808 3-Chlorophenol 98% 108-43-0 25g $49.3 2024-03-01 Buy
Sigma-Aldrich 8.20321 3-Chlorophenol for synthesis 108-43-0 10g $30.9 2024-03-01 Buy
Sigma-Aldrich 8.20321 3-Chlorophenol for synthesis 108-43-0 50g $121 2024-03-01 Buy
Sigma-Aldrich 8.20321 3-Chlorophenol for synthesis 108-43-0 250g $511 2024-03-01 Buy
Product number Packaging Price Buy
C62808 100g $40.56 Buy
C62808 25g $49.3 Buy
8.20321 10g $30.9 Buy
8.20321 50g $121 Buy
8.20321 250g $511 Buy

3-Chlorophenol Chemical Properties,Uses,Production

Chemical Properties

All isomers have a characteristic odor.

Chemical Properties

White to light yellow crystal.

Uses

3-Chlorophenol is generally used in building various polycyclic aromatic systems. It is also employed in palladium-catalyzed coupling reactions to synthesize aryl intermediates in synthetic organic chemistry.

Uses

3-Chlorophenol is a halophenol with antifungal activity. 3-Chlorophenol is commonly used as a building block in the preparation of variety of biologically active compounds. Studies suggest that 3-Chlo rophenol can be used in the regeneration of vegetal activated carbons.

Uses

3-Chlorophenol is widely used in the pharmaceutical, dyes and organic synthesis industry. It is an important intermediate in the synthesis of chemicals.

Definition

ChEBI: 3-chlorophenol is a monochlorophenol carrying the chloro substituent at position 3.

General Description

White crystals with an odor of phenol. Sinks in and slowly dissolves in water.

Air & Water Reactions

Discolors on exposure to air. Water soluble

Reactivity Profile

3-Chlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents .

Hazard

Toxic by skin absorption, inhalation, or ingestion.

Fire Hazard

3-Chlorophenol is probably combustible.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Questionable carcinogen with experimental tumorigenic data by skin contact. Mutation data reported. Flammable or combustible liquid. When heated to decomposition it emits toxic fumes of Cl-. See also CHLOROPHENOLS.

Potential Exposure

Monochlorophenols are used in the manufacture of fungicides, slimicides, bactericides, pesticides, herbicides, disinfectants, wood and glue preservatives; in the production of phenolic resins; in the extraction of certain minerals from coal; as a denaturant for ethanol; as an antiseptic; as a disinfectant, and others.

Shipping

UN 2020 (solid); UN2021 (liquid) Chlorophenols, solid and liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

It could not be obtained solid by crystallisation from pet ether. It is best purified by distillation under reduced pressure. [Beilstein 6 IV 810.]

Incompatibilities

May form explosive mixture with air. Contact with oxidizing agents can cause fire and explosion hazard. Heat produces hydrogen chloride and chlorine. Corrosive to aluminum, copper and other chemically active metals.

Waste Disposal

Incinerate in admixture with flammable solvent in furnace equipped with afterburner and scrubber.

24318-02-3
108-43-0
Synthesis of 3-Chlorophenol from 1-chloro-3-phenylmethoxy-benzene
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View Lastest Price from 3-Chlorophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Chlorophenol pictures 2023-08-12 3-Chlorophenol
108-43-0
US $0.00-0.00 / kg 1kg 99% 100tons Hebei Yanxi Chemical Co., Ltd.
 3-Chlorophenol pictures 2023-03-06 3-Chlorophenol
108-43-0
US $10.60 / KG 1KG 99% 5000kg Hebei Guanlang Biotechnology Co,.LTD
3-Chlorophenol pictures 2021-11-18 3-Chlorophenol
108-43-0
US $10.00 / Kg/Bag 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd
  • 3-Chlorophenol pictures
  • 3-Chlorophenol
    108-43-0
  • US $0.00-0.00 / kg
  • 99%
  • Hebei Yanxi Chemical Co., Ltd.
  •  3-Chlorophenol pictures
  • 3-Chlorophenol
    108-43-0
  • US $10.60 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co,.LTD
  • 3-Chlorophenol pictures
  • 3-Chlorophenol
    108-43-0
  • US $10.00 / Kg/Bag
  • 99%
  • Hebei Zhanyao Biotechnology Co. Ltd
3-chloro-1-hydroxybenzene 3-chloro-pheno 3-Hydroxychlorobenzene m-chlorophenicacid 3-Chloro-1-benzenol 3-Cl-phenol 3-Chlorophenol,99% 3-Chlorophenol Standard 3-Chlorophenol 5g [108-43-0] Between chlorophenol 3-Chlorophenol, 99% 25GR 3-Chlorophenol, 99% 5GR NSC 59700 3-Chlorophenol solution Between chlorine phenol Inter-chlorophenol m-chloro-pheno meta-Chlorophenol Phenol, m-chloro- Phenol,3-chloro- CHLOROPHENOL(M-) 3-CHLOROPHENOL 3-Chlorophenol m-Chlorophenol 3-CHLOROPHENOL PESTANAL 3-Chlorophenol,>98% 3-MONOCHLOROPHENOL 3 Chloro phenol ( m Chloro phenol) CAS No 108-43-0 3-Chlorophenol > 3-ChlorophenolSolution,1000mg/L,1ml 3-ChlorophenolSolution,100mg/L,1ml 3-CHLOROPHENOL FOR SYNTHESIS 10 G 3-Chlorophenol pure, 98% 3-CHLOROPHENOL For Synthesis M-CHLOROPHENOL MONOCHLOROPHENOL 3-Chlorphenol Lenvatinib Impurity 22(3-Chlorophenol) 13C6]-3-Chlorophenol Lenvatinib Impurity 64 Lenvatinib Impurity 69 108-43-0 C6H5CIO 108430 C6H5OCl Organic Building Blocks Oxygen Compounds Phenols Building Blocks Pyridines Chlorine Compounds Phenols Alpha sort C CAlphabetic CH Pesticides&Metabolites Organic Building Blocks Oxygen Compounds