1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE structure

CAS No.: 39235-58-0

Chemical Name:: 1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE

Synonyms: Salbutamol Impurity 50;Ibandronate Impurity 28;4-hydroxy-3-hydroxymethylacetophenone;1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE;Ethanone, 1-[4-hydroxy-3-(hydroxymethyl)phenyl]-

CBNumber:: CB7750047

Molecular Formula:: C9H10O3

Molecular Weight:: 166.17

MDL Number:: MFCD00819312

MOL File:: Mol file

Last updated:2023-04-23 13:52:06

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1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Properties

Melting point	121 °C
Boiling point	381.4±32.0 °C(Predicted)
Density	1.247±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Acetone, Chloroform
form	Solid
pka	8.13±0.18(Predicted)
color	Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H312-H332
Precautionary statements	P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	H942975	1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-ethanone	39235-58-0	25mg	$335	2021-12-16	Buy
TRC	H942975	1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-ethanone	39235-58-0	10mg	$145	2021-12-16	Buy
Ambeed	A561164	1-(4-Hydroxy-3-(hydroxymethyl)phenyl)ethanone 95%	39235-58-0	5g	$159	2021-12-16	Buy
Ambeed	A561164	1-(4-Hydroxy-3-(hydroxymethyl)phenyl)ethanone 95%	39235-58-0	1g	$45	2021-12-16	Buy
Crysdot	CD12075898	1-(4-Hydroxy-3-(hydroxymethyl)phenyl)ethanone 95+%	39235-58-0	1g	$429	2021-12-16	Buy

Product number	Packaging	Price	Buy
H942975	25mg	$335	Buy
H942975	10mg	$145	Buy
A561164	5g	$159	Buy
A561164	1g	$45	Buy
CD12075898	1g	$429	Buy

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Chemical Properties,Uses,Production

Uses

1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-ethanone is an intermediate in synthesizing Albuterol Dimer Ether (A514520), which is an impurity of Albuterol (Salbutamol) (A514500). Albuterol impurity F. Albuterol is a β2-adrenoceptor agonist. Bronchodilator; tocolytic.

Preparation

Obtained by refluxing 3-chloromethyl-4-hydroxy-acetophenone with water for 3 h (70%).

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(3-CHLOROMETHYL-4-HYDROXY-PHENYL)-ETHANONE 4-Acetoxy-3-acetoxymethylacetophenone

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Suppliers

Global( 39)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
Changzhou PBpharmaceutical R&D Co.,Ltd	0519-83990708	info@pbpharm.com	CHINA	498	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2169	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19185	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Nanjing Chemlin Chemical Co., Ltd	025-83697070	info@chemlin.com.cn	China	17940	64
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	41132	60
ChemStrong Scientific Co.,Ltd	0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15878	55

Supplier	Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Changzhou PBpharmaceutical R&D Co.,Ltd	58
Changzhou Ditong Chemical Co.,Ltd	58
Aromsyn Co., Ltd.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Nanjing Chemlin Chemical Co., Ltd	64
Bide Pharmatech Ltd.	60
ChemStrong Scientific Co.,Ltd	56
Shanghai Macklin Biochemical Co.,Ltd.	55

1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE 4-hydroxy-3-hydroxymethylacetophenone Ethanone, 1-[4-hydroxy-3-(hydroxymethyl)phenyl]- Salbutamol Impurity 50 Ibandronate Impurity 28 39235-58-0