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2,5-Dichloropyrimidine

2,5-Dichloropyrimidine structure

CAS No.: 22536-67-0

Chemical Name:: 2,5-Dichloropyrimidine

Synonyms: EOS-60492;2,5-Dichlo;2,5-chloropyrimidine;2,5-DICHLOROPYRIMIDINE;Macitentan Impurity 32;2,5‐Dichloropyridimidine;2,5-Dichloro-1,3-diazine;Pyrimidine, 2,5-dichloro-;2,5-Dichloropyrimidine>2,5-Dichloropyrimidine 97%

CBNumber:: CB7750461

Molecular Formula:: C4H2Cl2N2

Molecular Weight:: 148.98

MDL Number:: MFCD00673131

MOL File:: 22536-67-0.mol

MSDS File:: SDS

Last updated:2024-04-08 17:36:13

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2,5-Dichloropyrimidine Properties

Melting point	48-55 °C
Boiling point	190°C
Density	1.493
Flash point	140°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	-2.84±0.22(Predicted)
form	Powder
color	Off-white
Water Solubility	Slightly soluble in water.
λmax	268nm(EtOH)(lit.)
InChI	InChI=1S/C4H2Cl2N2/c5-3-1-7-4(6)8-2-3/h1-2H
InChIKey	CEJAHXLRNZJPQH-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=C(Cl)C=N1
CAS DataBase Reference	22536-67-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07,GHS09

Signal word

Danger

Hazard statements

H302-H318-H400

Precautionary statements

P273-P280-P301+P312+P330-P305+P351+P338+P310

Hazard Codes

C,N,Xn

Risk Statements

22-41-50

Safety Statements

26-39-61

RIDADR

UN 3077 9/PG 3

WGK Germany

HazardClass

LACHRYMATOR, CORROSIVE

HazardClass

PackingGroup

Ⅲ

HS Code

29335990

NFPA 704

	1
2		0

2,5-Dichloropyrimidine price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	720917	2,5-Dichloropyrimidine 97%	22536-67-0	1g	$10.4	2024-03-01	Buy
TCI Chemical	D4045	2,5-Dichloropyrimidine >98.0%(GC)	22536-67-0	5g	$37	2024-03-01	Buy
TCI Chemical	D4045	2,5-Dichloropyrimidine >98.0%(GC)	22536-67-0	25g	$148	2024-03-01	Buy
Alfa Aesar	H64066	2,5-Dichloropyrimidine, 95%	22536-67-0	5g	$32.65	2024-03-01	Buy
Alfa Aesar	H64066	2,5-Dichloropyrimidine, 95%	22536-67-0	25g	$127.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
720917	1g	$10.4	Buy
D4045	5g	$37	Buy
D4045	25g	$148	Buy
H64066	5g	$32.65	Buy
H64066	25g	$127.65	Buy

2,5-Dichloropyrimidine Chemical Properties,Uses,Production

Uses

2,5-Dichloropyrimidine acid is employed as a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

Preparation

2,5-Dichloropyrimidine was synthesised from 2-hydroxypyrimidine hydrochloride by treatment with aqueous chlorine solution. Reaction of the product with phosphoryl chloride in the presence of N,N-dimethylaniline gave the desired product in 40% yield. The sample was then purified by sublimation.

storage

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

structure and hydrogen bonding

C₄H₂Cl₂N₂, M=148.98 monoclinic, space group P2_1/m with a=6.077(3), b=19.771(8), c=7.399(3) ?, β=101.23(6)°, U=872 ?³ [from 2θ values of 29 reflections measured at±ω, 25 ≤2θ ≤ 38°, λ = 0.710 73?, T=150.0 K], D_calc=1.702 g cm^-3, Z=6, μ =0.993 mm-1[1].

References

[1] Blake A, et al. Structure Analysis Restrained by ab Initio Calculations: The Molecular Structure of 2,5-Dichloropyrimidine in Gaseous and Crystalline Phases. The Journal of Physical Chemistry, 1996; 100: 12280–12287.

2,5-Dichloropyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

tert-Butyl 4-(5-chloropyrimidin-2-yl)piperazine-1-carboxylate 2,5-Dichloro-4-iodopyrimidine 5-chloro-2-methoxy-pyrimidine 2(1H)-Pyrimidinethione, 5-chloro- (9CI)

2,5-Dichloropyrimidine Suppliers

Global( 307)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Fullone Chemical Co., Ltd.	+86-13328197671 +86-13861172460	sales@borenchem.cn	China	1055	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7613	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1011	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2169	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58

Supplier	Advantage
Changzhou Fullone Chemical Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
Shanxi Naipu Import and Export Co.,Ltd	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Changzhou Ditong Chemical Co.,Ltd	58
Xi'an Kono chem co., Ltd.,	58

View Lastest Price from 2,5-Dichloropyrimidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-08	2,5-Dichloropyrimidine 22536-67-0	US $36.00-1.10 / kg	1kg	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-06-09	2,5-Dichloropyrimidine 22536-67-0	US $9.00 / KG	1KG	99.9	1 ton	Hebei Guanlang Biotechnology Co,.LTD
2022-10-18	2,5-Dichloropyrimidine 22536-67-0	US $30.00 / kg	1kg	99%	100 tons	Hebei Duling International Trade Co. LTD

2,5-Dichloropyrimidine
22536-67-0
US $36.00-1.10 / kg
99%
Henan Fengda Chemical Co., Ltd

2,5-Dichloropyrimidine
22536-67-0
US $9.00 / KG
99.9
Hebei Guanlang Biotechnology Co,.LTD

2,5-Dichloropyrimidine
22536-67-0
US $30.00 / kg
99%
Hebei Duling International Trade Co. LTD

2,5-Dichloropyrimidine Spectrum

2,5-Dichloropyrimidine(22536-67-0)¹HNMR

22536-67-0(2,5-Dichloropyrimidine)Related Search:

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2,5-DICHLOROPYRIMIDINE Pyrimidine, 2,5-dichloro- (7CI,8CI,9CI) 2,5-DICHLOROPYRIMIDINE,PURITY:95% MIN(HPLC) Pyrimidine, 2,5-dichloro- 2,5-chloropyrimidine 2,5-DichloropyriMidine 97+% 2,5-Dichloro-1,3-diazine 2,5-DichloropyriMidine 97+%, 5-DichloropyriMidine 97+% 2,5-Dichloropyrimidine 97% EOS-60492 2,5‐Dichloropyridimidine 2,5-Dichlo 2,5-DICHLOROPYRIMIDINE,PURITY Macitentan Impurity 32 2,5-Dichloropyrimidine> 22536-67-0 84-73-3 22536-60-0 Heterocycle-Pyrimidine series Building Blocks C4 to C5 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Pyrimidines Chlorinated heterocyclic series PYRIMIDINE Pyrimidine Series Pyridines, Pyrimidines, Purines and Pteredines