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QUAZINONE
- CAS No.
- 70018-51-8
- Chemical Name:
- QUAZINONE
- Synonyms
- Posicor;R 13-6438;QUAZINONE;Quazinona;Quazinonum;RO 13-6438;Unii-D1Q7F6C2fp;Quazinonum [latin];Quazinona [spanish];Quazinone (Ro 13-6438)
- CBNumber:
- CB7751165
- Molecular Formula:
- C11H10ClN3O
- Molecular Weight:
- 235.67
- MDL Number:
- MFCD00211176
- MOL File:
- 70018-51-8.mol
Last updated:2023-05-18 11:31:17
| storage temp. | RT |
|---|---|
| solubility | ethanol: soluble1mg/mL |
| form | White to off-white solid. |
| color | white |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months |
| FDA UNII | D1Q7F6C2FP |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
QUAZINONE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29151 | Quazinone | 70018-51-8 | 5mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 29151 | Quazinone | 70018-51-8 | 10mg | $104 | 2024-03-01 | Buy |
| Cayman Chemical | 29151 | Quazinone | 70018-51-8 | 25mg | $234 | 2024-03-01 | Buy |
| TRC | Q509453 | Quazinone(Ro13-6438) | 70018-51-8 | 25mg | $145 | 2021-12-16 | Buy |
| TRC | Q509453 | Quazinone(Ro13-6438) | 70018-51-8 | 10mg | $75 | 2021-12-16 | Buy |
QUAZINONE Chemical Properties,Uses,Production
Description
Ro 13-6438 (70018-51-8) is a selective inhibitor of phosphodiesterase III (PDE III, IC50 = 0.6 μM).
Uses
Cardiotonic.
Uses
Quazinone (Ro 13-6438) is a phosphodiesterase inhibitor and novel cardiotonic agent with vasodilating properties.
References
1) Eigenmann et al. (1984) Cardiovascular profile of Ro 13-6438, a novel positive inotropic agent with vasodilating properties; J. Cardiovasc. Pharmacol., 6 511 2) Holck et al. (1984) Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties; J. Cardiovasc. Pharmacol. 6 520
QUAZINONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 37)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Suzhou Zhixin Biotechnology Co., Ltd. | 0512-65118909 15162312715 | sales@szzxbio.com | China | 2949 | 58 |
QUAZINONE
R 13-6438
RO 13-6438
(3R)-6-Chloro-1,5-dihydro-3-methylimidazo[2,1-b]quinazolin-2(3H)-one
Posicor
Imidazo(2,1-B)quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-, (R)-
Quazinona
Quazinona [spanish]
Quazinonum
Quazinonum [latin]
Unii-D1Q7F6C2fp
IMidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-Methyl-, (3R)-
Quazinone (Ro 13-6438)
Ro 13-6438 (Quazinone)
70018-51-8
G Proteins and Cyclic Nucleotides
Cyclic Nucleotide Metabolism
Phosphodiesterase Inhibitors
BioChemical
Cell Biology
Cell Signaling and Neuroscience