ChemicalBook >> CAS DataBase List >>5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE structure

CAS No.: 131084-35-0

Chemical Name:: 5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE

Synonyms: CS-1071;CP 94253;CP94253HCl;CP 94253 Free base;CP 94253 HYDROCHLORIDE;CP-94,253 dihydrochloride;3-(1,2,5,6-tetrahydro-4-pyridyl)-5-propoxypyrrolo[3,2-b]pyridine;5-Propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine;5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine;1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-

CBNumber:: CB7761214

Molecular Formula:: C15H19N3O

Molecular Weight:: 257.33

MDL Number:: MFCD03453293

MOL File:: 131084-35-0.mol

MSDS File:: SDS

Last updated:2023-05-04 17:34:32

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5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Properties

Melting point	>230°C (dec.)
Boiling point	442.9±45.0 °C(Predicted)
Density	1.166
storage temp.	Desiccate at RT
solubility	H2O: soluble15mg/mL, clear
form	powder
pka	14.37±0.40(Predicted)
color	white to beige
FDA UNII	FYC6YY5RYL

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26
WGK Germany	3

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0588	CP-94,253 dihydrochloride ≥98% (HPLC)	131084-35-0	5mg	$119	2024-03-01	Buy
Sigma-Aldrich	SML0588	CP-94,253 dihydrochloride ≥98% (HPLC)	131084-35-0	25mg	$481	2024-03-01	Buy
Tocris	1317	CP94253hydrochloride ≥98%(HPLC)	131084-35-0	10	$210	2021-12-16	Buy
Tocris	1317	CP94253hydrochloride ≥98%(HPLC)	131084-35-0	50	$822	2021-12-16	Buy
Usbiological	255041	CP 94253 hydrochloride	131084-35-0	10mg	$466	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML0588	5mg	$119	Buy
SML0588	25mg	$481	Buy
1317	10	$210	Buy
1317	50	$822	Buy
255041	10mg	$466	Buy

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

CP 94253 Hydrochloride is a potent and selective serotonin 5-HT1B receptor agonist with anticonvulsant activity.

Definition

ChEBI: 5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine is a pyrrolopyridine.

Biological Activity

Potent, selective 5-HT 1B agonist (K i values are 89, 2, 860, 49 and 1,600 nM for 5-HT 1A , 5-HT 1B , 5-HT 1C , 5-HT 1D and 5-HT 2 receptors respectively). Centrally active upon systemic administration in vivo .

Biochem/physiol Actions

CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively. CP-94,253 was found to be anxiolytic in animal models; dose-dependently enhanced reinforcing effects of cocaine (self-administration);and reduced food intake.

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Suppliers

Global( 31)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Unipharm pharmaceutical industry Co., Ltd	536-8266195 +8613953676784	lee@unipharm-sd.com	China	1206	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
LETOPHARM LIMITED	+86-21-5821 5861	sales@letopharm.com	China	2384	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4121	55
AN PharmaTech Co Ltd	86(21)68097365	sales@anpharma.net	China	4901	55

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
Unipharm pharmaceutical industry Co., Ltd	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Amadis Chemical Company Limited	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
LETOPHARM LIMITED	58
Sigma-Aldrich	80
Shanghai Lollane Biological Technology Co.,Ltd.	55
AN PharmaTech Co Ltd	55

131084-35-0(5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE)Related Search:

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE 4-Azaindole 5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE CP 94253 HYDROCHLORIDE CP94253HCl 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridin hydrochloride CP 94253 3- (1,2,5,6-Tetrahydro-4-pyridyl)-5-propoxypyrrolo[3, 2-b] pyridine hydrochloride CP-94,253 dihydrochloride 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine 5-Propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine CS-1071 3-(1,2,5,6-tetrahydro-4-pyridyl)-5-propoxypyrrolo[3,2-b]pyridine 1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)- 5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine hydrochloride CP 94253 Free base 131084-35-0 C15H20N3OCl C15H19N3OHCl Serotonin receptor