(R)-(+)-1,2-Dithiolane-3-pentanoic acid
- CAS No.
- 1200-22-2
- Chemical Name:
- (R)-(+)-1,2-Dithiolane-3-pentanoic acid
- Synonyms
- (R)-LIPOIC ACID;R-ALPHA-LIPOIC ACID;Thiogamma;Tiobe;Lipoec;Tiobec;ipoic acid;(R)-(+)-α-L;D-lipoic acid;(R)-lipoicaci
- CBNumber:
- CB7765979
- Molecular Formula:
- C8H14O2S2
- Molecular Weight:
- 206.33
- MDL Number:
- MFCD01631142
- MOL File:
- 1200-22-2.mol
- MSDS File:
- SDS
| Melting point | 48-52 °C(lit.) |
|---|---|
| alpha | D23 +104° (c = 0.88 in benzene) |
| Boiling point | 185-195 °C(Press: 0.5 Torr) |
| Density | 1.218±0.06 g/cm3(Predicted) |
| refractive index | 114 ° (C=1, EtOH) |
| Flash point | >230 °F |
| storage temp. | -20°C |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO |
| form | Solid |
| pka | 5.4(at 25℃) |
| color | Light Yellow to Yellow |
| optical activity | [α]20/D +104°, c = 1 in chloroform |
| Merck | 14,9326 |
| LogP | 2.160 (est) |
| CAS DataBase Reference | 1200-22-2(CAS DataBase Reference) |
| FDA UNII | VLL71EBS9Z |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501 | |||||||||
| Risk Statements | 22-36/38 | |||||||||
| Safety Statements | 20-36-26-35 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
(R)-(+)-1,2-Dithiolane-3-pentanoic acid price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 07039 | (R)-(+)-α-Lipoic acid ≥98.0% (HPLC) | 1200-22-2 | 10mg | $72.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 04471 | (R)-(+)-α-Lipoic acid analytical standard | 1200-22-2 | 100mg | $208 | 2024-03-01 | Buy |
| TCI Chemical | L0207 | (R)-alpha-Lipoic Acid >98.0%(HPLC)(T) | 1200-22-2 | 5g | $100 | 2024-03-01 | Buy |
| TCI Chemical | L0207 | (R)-alpha-Lipoic Acid >98.0%(HPLC)(T) | 1200-22-2 | 25g | $182 | 2024-03-01 | Buy |
| Cayman Chemical | 27299 | (R)-α-Lipoic Acid | 1200-22-2 | 5g | $86 | 2024-03-01 | Buy |
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Chemical Properties,Uses,Production
Chemical Properties
Yellow Crystalline Solid
Uses
α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.
Uses
A fat-metabolism stimulator
Definition
ChEBI: (R)-lipoic acid is the (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. It has a role as a prosthetic group, a nutraceutical and a cofactor. It is a lipoic acid, a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It is functionally related to an octanoic acid. It is a conjugate acid of a (R)-lipoate. It is an enantiomer of a (S)-lipoic acid.
General Description
α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.
Biochem/physiol Actions
(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.
(R)-(+)-1,2-Dithiolane-3-pentanoic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Biopole Pharmatech Co., Ltd. | +8615151475053 | biopole@163.com | China | 37 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Shandong Luning Pharmaceutical Co., Ltd. | 0546-6491488 +8613305469775 | China | 40 | 58 | |
| Hebei Dangtong Import and export Co LTD | +8615632927689 | admin@hbdangtong.com | China | 991 | 58 |
| PNP Biotech Co. Ltd | +8618516098983 | sales@pnpbiotech.com | China | 1001 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 269 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7377 | 58 |
| Hebei Kangcang new material Technology Co., LTD | +8619133911216 | Jany1001@kangcang.com.cn | China | 338 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
View Lastest Price from (R)-(+)-1,2-Dithiolane-3-pentanoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-19 | lipoic acid
1200-22-2
|
US $9.00-70.00 / g | 10g | 99% | 10 tons | Hebei Kangcang new material Technology Co., LTD | |
 |
2024-04-19 | (R)-(+)-1,2-Dithiolane-3-pentanoic acid
1200-22-2
|
US $50.00-40.00 / kg | 1kg | 99% | 20 | Hebei Dangtong Import and export Co LTD | |
 |
2024-04-18 | (R)-(+)-1,2-Dithiolane-3-pentanoic acid
1200-22-2
|
US $0.00-0.00 / kg | 1kg | 99% | 20t | Jinan Jianfeng Chemical Co., Ltd |
-
- lipoic acid
1200-22-2
- US $9.00-70.00 / g
- 99%
- Hebei Kangcang new material Technology Co., LTD
-
- (R)-(+)-1,2-Dithiolane-3-pentanoic acid
1200-22-2
- US $50.00-40.00 / kg
- 99%
- Hebei Dangtong Import and export Co LTD
-
- (R)-(+)-1,2-Dithiolane-3-pentanoic acid
1200-22-2
- US $0.00-0.00 / kg
- 99%
- Jinan Jianfeng Chemical Co., Ltd
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