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2-Methyl butyric acid

Description References
2-Methyl butyric acid
2-Methyl butyric acid structure
Chemical Name:
2-Methyl butyric acid
NSC 7304;FEMA 2695;2-Methylbutyri;2-methylbutyric;2-methylbutyrate;Hydroangelic acid;activevalericacid;CARBOXYLIC ACID C5;RARECHEM AL BO 0094;2-Methybutyric acid
Molecular Formula:
Formula Weight:
MOL File:

2-Methyl butyric acid Properties

Melting point:
-70 °C
Boiling point:
176-177 °C(lit.)
0.936 g/mL at 25 °C(lit.)
vapor pressure 
0.5 mm Hg ( 20 °C)
refractive index 
n20/D 1.405(lit.)
Flash point:
165 °F
storage temp. 
4.8(at 25℃)
Clear colorless to pale yellow
explosive limit
Water Solubility 
45 g/L (20 ºC)
JECFA Number
CAS DataBase Reference
116-53-0(CAS DataBase Reference)
NIST Chemistry Reference
Butanoic acid, 2-methyl-(116-53-0)
EPA Substance Registry System
Butanoic acid, 2-methyl-(116-53-0)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  C
Risk Statements  21/22-34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 3
WGK Germany  1
RTECS  EK7897000
HazardClass  8
PackingGroup  III
HS Code  29156090
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning P234, P390, P404
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P234 Keep only in original container.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P390 Absorb spillage to prevent material damage.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

2-Methyl butyric acid price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 193070 2-Methylbutyric acid 98% 116-53-0 25g $31.7 2018-11-13 Buy
Sigma-Aldrich 193070 2-Methylbutyric acid 98% 116-53-0 100g $58.9 2018-11-13 Buy
TCI Chemical M0181 DL-2-Methylbutyric Acid >97.0%(GC) 116-53-0 25mL $29 2018-11-22 Buy
TCI Chemical M0181 DL-2-Methylbutyric Acid >97.0%(GC) 116-53-0 500mL $89 2018-11-22 Buy
Alfa Aesar A11546 2-Methylbutyric acid, 98% 116-53-0 500ml $137 2018-11-13 Buy

2-Methyl butyric acid Chemical Properties,Uses,Production


2-methyl butyric acid has a pungent, acrid odor which is similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant fruity taste. It can be prepared either by decarboxylation of methyl ethyl malonic acid or by the oxidation of fermentation amyl alcohol (fusel oil). It is used as a flavor ingredient for butter, cream, cheese flavor deployment. It also provides acyl moiety for the preparation of the respective flavor esters.


[1] George A. Burdock, Encyclopedia of Food and Color Additives, Band 1, 1996
[2] T. Tachihara, H. Hashimoto, S. Ishizaki, T. Komai, A. Fujita, M. Ishikawa and T. Kitahara, Microbial resolution of 2-methylbutyric acid and its application to several chiral flavour compounds, Developments in Food Science, 2006, vol. 43, 97-100

Chemical Properties

clear colorless to pale yellowish liquid


Used in the synthesis of 2-methylbutyric anhydride


ChEBI: A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria.

2-Methyl butyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-Methyl butyric acid Suppliers

Global( 219)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21954 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20680 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 CHINA 1367 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Hebei Aicrowe Biotech Co., Ltd
0311-66855331 CHINA 240 58
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6374 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4669 58
career henan chemical co
+86-371-86658258 CHINA 20516 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 CHINA 3623 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76

View Lastest Price from 2-Methyl butyric acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-05-20 2-methyl butyric acid/DL-2-Methylbutyric acid 116-53-0
US $20.00 / Kg/Drum 1g 99.8% 5000 Hebei Aicrowe Biotech Co., Ltd
2018-12-17 2-Methyl butyric acid
US $1.00 / kg 1kg 99% 100KG career henan chemical co

2-Methyl butyric acid Spectrum

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