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4-AMINO-N,N-DIMETHYLBENZYLAMINE

4-AMINO-N,N-DIMETHYLBENZYLAMINE structure

CAS No.: 6406-74-2

Chemical Name:: 4-AMINO-N,N-DIMETHYLBENZYLAMINE

Synonyms: Nsc 207808;Einecs 229-033-0;p-Aminobenzyldimethylamine;4-DIMETHYLAMINOMETHYL-ANILINE;4-AMINO-N,N-DIMETHYLBENZYLAMINE;4-AMINOBENZYL-N,N-DIMETHYLAMINE;N,N-DiMethyl-4-aMinobenzylaMine;N-(4-AMINOBENZYL)-N,N-DIMETHYLAMINE;4-[(Dimethylamino)methyl]benzenamine;4-((dimmethylamino)methyl)benzenamine

CBNumber:: CB7767069

Molecular Formula:: C9H14N2

Molecular Weight:: 150.22

MDL Number:: MFCD00035953

MOL File:: 6406-74-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:53

Product description	Number	Pack Size	Price
4-Amino-N,N-dimethylbenzylamine 95+%	074353	1g	$71
4-((dimethylamino)methyl)benzenamine	BP-21733	1g	$59
4-Amino-N,N-dimethylbenzylamine 95+%	074353	5g	$215
4-Amino-N,N-dimethylbenzylamine 95+%	074353	10g	$374
4-Amino-N,N-dimethylbenzylamine	J53165	10g	$220
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4-AMINO-N,N-DIMETHYLBENZYLAMINE Properties

Boiling point	231.8±15.0 °C(Predicted)
Density	1.013±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	9.34±0.28(Predicted)
Appearance	Colorless to light yellow Solid-Liquid Mixture
FDA UNII	ELP6J7CU5V
EPA Substance Registry System	p-Aminobenzyldimethylamine (6406-74-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2921599090

4-AMINO-N,N-DIMETHYLBENZYLAMINE price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	074353	4-Amino-N,N-dimethylbenzylamine 95+%	6406-74-2	1g	$71	2021-12-16	Buy
BroadPharm	BP-21733	4-((dimethylamino)methyl)benzenamine	6406-74-2	1g	$59	2021-12-16	Buy
Matrix Scientific	074353	4-Amino-N,N-dimethylbenzylamine 95+%	6406-74-2	5g	$215	2021-12-16	Buy
Matrix Scientific	074353	4-Amino-N,N-dimethylbenzylamine 95+%	6406-74-2	10g	$374	2021-12-16	Buy
AK Scientific	J53165	4-Amino-N,N-dimethylbenzylamine	6406-74-2	10g	$220	2021-12-16	Buy

Product number	Packaging	Price	Buy
074353	1g	$71	Buy
BP-21733	1g	$59	Buy
074353	5g	$215	Buy
074353	10g	$374	Buy
J53165	10g	$220	Buy

4-AMINO-N,N-DIMETHYLBENZYLAMINE Chemical Properties,Uses,Production

Uses

4-Amino-N,N-dimethylbenzylamine is a reagent in the reaction with methoxycarbonylphenyl isocyanate, in the synthesis of 4H-?3,?1-?benzoxazin-?4-?ones as potent alternate substrate inhibitors of human leukocyte elastase.

Synthesis

N,N-dimethyl-1-(4-nitrophenyl)methanamine

15184-96-0

6406-74-2

General procedure for the synthesis of 4-dimethylaminomethyl-aniline from N,N-dimethyl-4-nitrobenzylamine: to a solution of N,N-dimethyl-4-nitrobenzylamine (1 g, 5.55 mmol) in acetic acid (10 ml) was added activated iron powder (3 g), and the reaction mixture was stirred for 5 hr at 80 °C. After completion of the reaction, the reaction mixture was filtered; the filtrate was diluted with water and neutralized with 10% sodium hydroxide solution. The product was extracted with ethyl acetate, the organic layers were combined, dried with anhydrous sodium sulfate, filtered and the solvent was evaporated to give the crude product. The crude product was purified by silica gel column chromatography using chloroform/methanol (98:2, v/v) as eluent to give 4-dimethylaminomethyl-aniline (0.7 g, 85% yield).

References

[1] RSC Advances, 2015, vol. 5, # 58, p. 47125 - 47130
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 7, p. 2975 - 2990
[3] Patent: WO2006/123145, 2006, A1. Location in patent: Page/Page column 58
[4] European Journal of Medicinal Chemistry, 2014, vol. 86, p. 257 - 269
[5] Archiv der Pharmazie, 2014, vol. 347, # 12, p. 936 - 949

4-AMINO-N,N-DIMETHYLBENZYLAMINE synthesis

Synthesis of 4-AMINO-N,N-DIMETHYLBENZYLAMINE from 4-AMINO-N,N-DIMETHYLBENZAMIDE

4-AMINO-N,N-DIMETHYLBENZYLAMINE Preparation Products And Raw materials

Raw materials

N-Bromosuccinimide Hydrazine hydrate 4-Nitrotoluene Iron chloride hexahydrate Dimethylamine

4-AMINO-N,N-DIMETHYLBENZAMIDE N,N-dimethyl-1-(4-nitrophenyl)methanamine 4-Amino-N-methylbenzylamine 4-Aminobenzylamine BenzeneethanaMine, N-Methyl-4-nitro-

Hydrochloric acid 4-Nitrobenzyl chloride Dimethyl carbonate 4-Aminobenzoic acid 4-Nitrobenzyl bromide

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Preparation Products

(Z)-3-(((4-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-6-iodoindolin-2-one

4-AMINO-N,N-DIMETHYLBENZYLAMINE Suppliers

Global( 128)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10035	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10237	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hubei Ipure Biology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 4-AMINO-N,N-DIMETHYLBENZYLAMINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	4-AMINO-N,N-DIMETHYLBENZYLAMINE 6406-74-2	US $1.00 / KG	1KG	99%	Customized	Career Henan Chemical Co

4-AMINO-N,N-DIMETHYLBENZYLAMINE
6406-74-2
US $1.00 / KG
99%
Career Henan Chemical Co

4-AMINO-N,N-DIMETHYLBENZYLAMINE Spectrum

4-AMINO-N,N-DIMETHYLBENZYLAMINE(6406-74-2)¹HNMR

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p-Aminobenzyldimethylamine N-(4-AMINOBENZYL)-N,N-DIMETHYLAMINE N-[4-(AMINOMETHYL)PHENYL]-N,N-DIMETHYLAMINE 4-AMINOBENZYL-N,N-DIMETHYLAMINE 4-DIMETHYLAMINOMETHYL-ANILINE 4-AMINO-N,N-DIMETHYLBENZYLAMINE 4-((dimmethylamino)methyl)benzenamine Benzenemethanamine, 4-amino-N,N-dimethyl- (9CI) 4-[(Dimethylamino)methyl]benzenamine N,N-Dimethyl-4-aminobenzenemethaneamine 4-Amino-N,N-dimethylBenzenemethanamine Benzenemethanamine, 4-amino-N,N-dimethyl- Einecs 229-033-0 Nsc 207808 N,N-DiMethyl-4-aMinobenzylaMine 6406-74-2 AMINEPRIMARY Amines and Anilines