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L-NIO DIHYDROCHLORIDE

CAS No.
36889-13-1
Chemical Name:
L-NIO DIHYDROCHLORIDE
Synonyms
L-NIO;L-NIO, 2HCL;L-NIO dihydrochlorid;L-NIO (hydrochloride);L-NIO DIHYDROCHLORIDE;n(g)-iminoethylornithine;L-N5-(1-Iminoethyl)ornithine;L-Ornithine, N5-(1-iminoethyl)-;L-NIO DIHYDROCHLORIDE USP/EP/BP;L-N5-(1-Iminoethyl)Ornithine,HCl
CBNumber:
CB7776636
Molecular Formula:
C7H15N3O2
Molecular Weight:
173.21
MDL Number:
MFCD09878280
MOL File:
36889-13-1.mol
Last updated:2023-05-18 11:31:03

L-NIO DIHYDROCHLORIDE Properties

Melting point 225-226°C
storage temp. -20°C
solubility Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
Stability Hygroscopic
FDA UNII XQ6P9GL3YT

SAFETY

Risk and Safety Statements

Safety Statements  24/25
HS Code  29224985

L-NIO DIHYDROCHLORIDE price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 80320 L-NIO (hydrochloride) ≥95% 36889-13-1 5mg $17 2024-03-01 Buy
Cayman Chemical 80320 L-NIO (hydrochloride) ≥95% 36889-13-1 10mg $30 2024-03-01 Buy
Cayman Chemical 80320 L-NIO (hydrochloride) ≥95% 36889-13-1 50mg $118 2024-03-01 Buy
Cayman Chemical 80320 L-NIO (hydrochloride) ≥95% 36889-13-1 100mg $207 2024-03-01 Buy
Tocris 0546 L-NIOdihydrochloride 36889-13-1 10 $86 2021-12-16 Buy
Product number Packaging Price Buy
80320 5mg $17 Buy
80320 10mg $30 Buy
80320 50mg $118 Buy
80320 100mg $207 Buy
0546 10 $86 Buy

L-NIO DIHYDROCHLORIDE Chemical Properties,Uses,Production

Description

L-NIO is a non-selective inhibitor of all NOS isoforms. The Ki values for nNOS (rat), eNOS (bovine), and iNOS (mouse) are 1.7, 3.9, and 3.9 μM, respectively. L-NIO inhibits endothelial-dependent relaxation induced by acetylcholine in rat aortic rings and hypotensive responses to acetylcholine and bradykinin.

Chemical Properties

White Crystalline Solid

Uses

A potent and reversible inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells

Definition

ChEBI: L-NIO is a L-alpha-amino acid.

Biological Activity

Potent inhibitor of endothelial NO synthase (IC 50 = 500 nM). Also inhibits iNOS and nNOS. Active in vivo .

L-NIO DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

L-NIO DIHYDROCHLORIDE Suppliers

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29831 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8475 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006608290; 18621169109 market03@meryer.com China 40241 62
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17779 75
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shandong Ono Chemical Co., Ltd. 0539-6362799 20) China 10007 58
N5-(1-IMINOETHYL)-L-ORNITHINE DIHYDROCHLORIDE N(5)-(1-IMINOETHYL)-L-ORNITHINE HCL N5-(1-IMINOETHYL)-L-ORNITHINE HYDROCHLORIDE L-N5-(I-IMINOETHYL)ORNITHINE HYDROCHLORI DE POTENT IRREVERSIBLE N L-N5-(1-Iminoethyl)Ornithine,HCl L-NIO DIHYDROCHLORIDE L-N5-(1-IMINOETHYL)-ORNITHINE 2HCL L-N5-(1-IMINOETHYL)ORNITHINE, DIHYDROCHLORIDE L-N5-(1-IMINOETHYL) ORNITHINE, HYDROCHLORIDE L-N5-(I-IMINOETHYL)ORNITHINE HYDROCHLORIDE L-NIO (hydrochloride) L-N5-(1-Iminoethyl)ornithine L-N5-(1-Iminoethyl)-ornithine dihydrochloride,97% L-NIO L-NIO, 2HCL n(g)-iminoethylornithine NG-(1-IMINOETHYL)-L-ORNITHINE HYDROCHLORIDE L-Ornithine, N5-(1-iminoethyl)- L-NIOdihydrochloride,N5-(1-Iminoethyl)-L-ornithinedihydrochloride L-NIO DIHYDROCHLORIDE USP/EP/BP L-NIO dihydrochlorid 36889-13-1 C7H15N3O2HCl C7H16ClN3O2 C7H15N3O22HCl Amino Acids 13C, 2H, 15N Amino Acids & Derivatives Nitric Oxide Reagents Nitric Oxide