6-Mercaptohexan-1-ol
- CAS No.
- 1633-78-9
- Chemical Name:
- 6-Mercaptohexan-1-ol
- Synonyms
- 6-MERCAPTO-1-HEXANOL;6-MCH;6-MERCAPTOHEXAN-1-OL;1-Hexanol, 6-mercapto-;6-Mercapto-1-hexanol>6-Hydroxy-1-hexanethiol;6-Mercapto-1-hexanol 97%;6-Mercapto-1-hexanol ,97%;6-Hydrosulphonyl-1-Hexanol;6-Hydroxy-1-hexanethiol 6-MCH 6-Mercaptohexan-1-ol 6-Mercaptohexanol MCH
- CBNumber:
- CB7778009
- Molecular Formula:
- C6H14OS
- Molecular Weight:
- 134.24
- MDL Number:
- MFCD00068552
- MOL File:
- 1633-78-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Mercapto-1-hexanol 97% | 451088 | 5ml | $89.3 |
| 6-Mercapto-1-hexanol 97% | 451088 | 25ml | $298 |
| 6-Mercapto-1-hexanol >98.0%(GC) | M2266 | 5g | $96 |
| 6-Mercapto-1-hexanol >98.0%(GC) | M2266 | 25g | $380 |
| 6-Mercapto-1-hexanol 99% | 725226 | 1g | $277 |
| More product size | |||
| Boiling point | 225 °C(lit.) |
|---|---|
| Density | 0.981 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | 10.47±0.10(Predicted) |
| form | liquid |
| color | Colourless |
| BRN | 1846871 |
| Stability | Air Sensitive |
| InChI | InChI=1S/C6H14OS/c7-5-3-1-2-4-6-8/h7-8H,1-6H2 |
| InChIKey | UGZAJZLUKVKCBM-UHFFFAOYSA-N |
| SMILES | C(O)CCCCCS |
| LogP | 1.370 (est) |
| EPA Substance Registry System | 1-Hexanol, 6-mercapto- (1633-78-9) |
| UNSPSC Code | 12352300 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 3334 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-13-23 | |||||||||
| HS Code | 29309090 | |||||||||
| NFPA 704 |
|
6-Mercaptohexan-1-ol price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 451088 | 6-Mercapto-1-hexanol 97% | 1633-78-9 | 5ml | $89.3 | 2025-07-31 | Buy |
| Sigma-Aldrich | 451088 | 6-Mercapto-1-hexanol 97% | 1633-78-9 | 25ml | $298 | 2025-07-31 | Buy |
| TCI Chemical | M2266 | 6-Mercapto-1-hexanol >98.0%(GC) | 1633-78-9 | 5g | $96 | 2025-07-31 | Buy |
| TCI Chemical | M2266 | 6-Mercapto-1-hexanol >98.0%(GC) | 1633-78-9 | 25g | $380 | 2025-07-31 | Buy |
| Sigma-Aldrich | 725226 | 6-Mercapto-1-hexanol 99% | 1633-78-9 | 1g | $277 | 2025-07-31 | Buy |
6-Mercaptohexan-1-ol Chemical Properties,Uses,Production
Chemical Properties
Colorless to light yellow liquid
Uses
MCH is coated on a piezoelectric crystal which can be used for the fabrication of chemical sensor to differentiate between cheese varieties. Self assembled monolayers of MCH can be used on gold surfaces for bio-sensing applications. It can also be used as a monolayer for the surface modification of gold-polyaniline (Au-PANI) nanocomposites for the development of aptamer based biosensors (aptasensors).
Uses
This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with alcohols can be further functionalized with various groups even when attached to gold nanoclusters.
Uses
6-Mercapto-1-hexanolcan be used as a chemical linker for anchoring biological molecules to gold surfaces.
General Description
6-mecapto-1-hexanol (MCH) forms a self-assembled monolayer (SAM) with identically represented C6 spacer. MCH is a tool for surface coating that enables blocking of active sites and non-specific absorption.
reaction suitability
reagent type: linker
Synthesis
4286-55-9
1633-78-9
The general procedure for the synthesis of 6-mercaptohexan-1-ol from 6-bromohexanol was as follows: 6-bromohexanol (1 g, 5.60 mmol) was mixed with thiourea (0.64 g, 8.40 mmol) and NaOH (0.1 M) in 1,4-dioxane (4 mL), and the reaction was carried out at reflux for 4 hours. After completion of the reaction, the reaction mixture was cooled and the solvent was removed under vacuum. Subsequently, the pH of the reaction mixture was adjusted to 4 by addition of dilute hydrochloric acid. hydrochloric acid and thiol derivatives in the reaction mixture were extracted with dichloromethane. The organic layer was dried with anhydrous sodium sulfate and then concentrated to give 6-mercaptohexan-1-ol as a yellow oil. Yield: 0.563 g (75%). The structure of the product was determined by 1H NMR (500 MHz, DMSO-d6, TMS): δ 3.65 (s, 1H), 3.5 (t, 2H, J = 2.4Hz), 2.56 (t, 2H, J = 2.3Hz), 1.52-1.57 (m, 4H), 1.5 (s, 1H), 1.41-1.44 (m, 4H); 13C NMR ( 125 MHz, DMSO): δ 62.8,34.5,32.3,28.2,24.9,24.6; ESI-MS: m/z calculated values. For C6H14OS: 134.08, measured value: 135.11 (M++1) for confirmation.
References
[1] Journal of Chemical Sciences, 2018, vol. 130, # 10,
[2] Journal of Organic Chemistry, 1999, vol. 64, # 13, p. 4959 - 4961
[3] Chemical Physics Letters, 1997, vol. 264, # 3-4, p. 376 - 380
[4] Chemistry Letters, 1996, # 8, p. 635 - 636
[5] Chemistry Letters, 1996, # 8, p. 635 - 636
6-Mercaptohexan-1-ol Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou BEC Biological Technology Co., Ltd. | +undefined13771885869 | all@bek.com.cn | China | 62 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13505 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD. | +86-0532-8699-9256 +8615254267723 | kaley@cnfdevelop.com | China | 1410 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8830 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11883 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 6-Mercaptohexan-1-ol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-06 | 6-Mercaptohexan-1-ol
1633-78-9
|
US $1.00 / KG | 1KG | 95-99% | 100kg/week | Career Henan Chemical Co |
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- 6-Mercaptohexan-1-ol
1633-78-9
- US $1.00 / KG
- 95-99%
- Career Henan Chemical Co
