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FMOC-VAL-OSU

FMOC-VAL-OSU structure

CAS No.: 130878-68-1

Chemical Name:: FMOC-VAL-OSU

Synonyms: FMOC-VAL-OSU;Fmoc-Val-0su;Fmoc-L-Val-OSu;FMOC-VALINE-OSU;Fmoc-L-valine-osu;FMOC-VAL-OSUFMOC-V;Fmoc-Val-OSu, 98%, Fmoc-amino acids;N-Fmoc-L-valine N-succinimidyl ester;Trastuzumab Impurity 1 (Fmoc-Val-Osu);N-Fmoc-L-valineN-succinimidylester,95%

CBNumber:: CB7779662

Molecular Formula:: C24H24N2O6

Molecular Weight:: 436.46

MDL Number:: MFCD00153370

MOL File:: 130878-68-1.mol

Last updated:2025-07-24 18:13:43

Product description	Number	Pack Size	Price
Fmoc-Val-Osu	450869	100mg	$305
Fmoc-L-valine N-hydroxysuccinimide ester	276075	25g	$523
Fmoc-Val-Osu	F861083	1g	$75
Fmoc-Val-Osu	F861083	100mg	$45
Fmoc-Val-OSu,98%,Fmoc-aminoacids	JK598773	1g	$46
More product size

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FMOC-VAL-OSU Properties

Density	1.35±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	10.09±0.46(Predicted)
color	Off-white to white
optical activity	Consistent with structure
Water Solubility	Slightly soluble in water.

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P302+P352-P305+P351+P338-P362+P364

Safety Statements

24/25

HS Code

29251900

NFPA 704

	1
0		0

FMOC-VAL-OSU price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	450869	Fmoc-Val-Osu	130878-68-1	100mg	$305	2021-12-16	Buy
Usbiological	276075	Fmoc-L-valine N-hydroxysuccinimide ester	130878-68-1	25g	$523	2021-12-16	Buy
TRC	F861083	Fmoc-Val-Osu	130878-68-1	1g	$75	2021-12-16	Buy
TRC	F861083	Fmoc-Val-Osu	130878-68-1	100mg	$45	2021-12-16	Buy
Frontier Specialty Chemicals	JK598773	Fmoc-Val-OSu,98%,Fmoc-aminoacids	130878-68-1	1g	$46	2021-12-16	Buy

Product number	Packaging	Price	Buy
450869	100mg	$305	Buy
276075	25g	$523	Buy
F861083	1g	$75	Buy
F861083	100mg	$45	Buy
JK598773	1g	$46	Buy

FMOC-VAL-OSU Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

N-Fmoc-L-valine N-succinimidyl ester is useful for solid phase peptide synthesis techniques.

Synthesis

6066-82-6

68858-20-8

130878-68-1

Dicyclohexylcarbodiimide (1.55 g, 7.52 mmol) and N-hydroxysuccinimide (762 mg, 6.63 mmol) were sequentially added to a stirred solution of Fmoc-L-valine (1.5 g, 4.42 mmol) in dichloromethane (25 mL) at room temperature. The reaction mixture was stirred continuously for 3 hours at room temperature. Upon completion of the reaction, the white solid dicyclohexylurea produced in the reaction was removed by filtration. The organic phase was washed sequentially with 0.1 N HCl solution and deionized water, followed by drying with anhydrous sodium sulfate. The solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by fast column chromatography using 1% dichloromethane solution in methanol as eluent to give the final target product (S)-2,5-dioxopyrrolidin-1-yl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutyrate as a white solid (1.7 g, 89% yield). Mass spectrum (MS): m/z 459 [M + Na]+. 1H NMR (400 MHz, CDCl3) δ 7.80 (d, J = 7.5 Hz, 2H), 7.68-7.55 (m, 2H), 7.43 (t, J = 7.4 Hz, 2H), 7.34 (dd, J = 15.9, 8.5 Hz, 2H), 4.70 (d, J = 4.6 Hz, 1H), 4.56-4.40 (m, 3H), 4.28 (t, J = 6.6 Hz, 1H), 2.85 (s, 4H), 2.37 (dd, J = 12.3, 6.5 Hz, 1H), 1.08 (dd, J = 11.0, 6.9 Hz, 6H).

References

[1] Journal of Pharmaceutical Sciences, 1994, vol. 83, # 7, p. 999 - 1005
[2] Langmuir, 2010, vol. 26, # 7, p. 4990 - 4998
[3] Patent: WO2018/178060, 2018, A1. Location in patent: Page/Page column 64-66
[4] Journal of the American Chemical Society, 2015, vol. 137, # 21, p. 6932 - 6940
[5] Patent: US2017/247324, 2017, A1. Location in patent: Paragraph 0284; 0285

FMOC-VAL-OSU Preparation Products And Raw materials

Raw materials

N-Hydroxysuccinimide FMOC-L-Valine Dichloromethane Dicyclohexylcarbodiimide

Preparation Products

Val-cit-PAB-OH Fmoc-Val-Ala-PAB-OH MC-Val-Cit-PAB FMoc-Val-Cit-PAB FMoc-Val-Cit-PAB-PNP

Mc-Val-Cit-PABC-PNP

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FMOC-VAL-OSU Suppliers

Global( 163)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+8617390183901	cynthia@enlaibio.com	China	1100	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Sichuan Jiaying Lai Technology Co.,LTD	18716376478	ycling@enlaibio.com	CHINA	302	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shandong chuangyingchemical Co., Ltd.	58
Sichuan Jiaying Lai Technology Co.,LTD	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
GL Biochem (Shanghai) Ltd.	58
GL Biochem(Binhai) Ltd.	58

View Lastest Price from FMOC-VAL-OSU manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-17	Fmoc-L-Val-Osu 130878-68-1	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2025-09-23	FMOC-VAL-OSU 130878-68-1	US $0.00-0.00 / KG	1KG	98%	2000	Shenzhen Nexcon Pharmatechs Ltd.
2020-01-06	fmoc-val-osu 130878-68-1	US $1.00 / g	1g	98%	100KG	Sichuan Jiaying Lai Technology Co.,LTD

Fmoc-L-Val-Osu
130878-68-1
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

FMOC-VAL-OSU
130878-68-1
US $0.00-0.00 / KG
98%
Shenzhen Nexcon Pharmatechs Ltd.

fmoc-val-osu
130878-68-1
US $1.00 / g
98%
Sichuan Jiaying Lai Technology Co.,LTD

130878-68-1(FMOC-VAL-OSU)Related Search:

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FMOC-TYR(TBU)-OPFP FMOC-TYR(SO3H)-OH SODIUM SALT FMOC-D-TYR(TBU)-OPFP FMOC-D-PRO-OPFP FMOC-D-SER(TBU)-OPFP

FMOC-D-THR(TBU)-OPFP L-Valine FMOC-GLY-OSU FMOC-ILE-OSU FMOC-ALA-OSU

FMOC-VAL-OSU FMOC-VAL-OSU FMOC-L-VALINOL

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CarbaMic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-Methylpropyl]-, 9H-fluoren-9-ylMethyl ester, (S)- L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-,2,5-dioxo-1-pyrrolidinyl ester N-Fmoc-L-valine N-succinimidyl ester Fmoc-L-valineN-hydroxysuccinimide ester≥ 99% (HPLC) FMOC-L-VALINE N-HYDROXYSUCCINIMIDE ESTER FMOC-VAL-OSU FMOC-VALINE-OSU NALPHA-9-Fluorenylmethoxycarbonyl-L-valine N-hydroxysuccinimide ester Fmoc-L-Val-OSu N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-valine succinimidyl ester (S)-2,5-dioxopyrrolidin-1-yl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-methylbutanoate N-alpha-FMoc-L-valine N-hydroxysucciniMide ester [(1S)-1-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylpropyl] 9H-fluoren-9-ylmethyl carbamate N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valine 2,5-dioxo-1-pyrrolidinyl ester FMOC-VAL-OSUFMOC-V (9H-Fluoren-9-yl)MethOxy]Carbonyl Val-OSu Fmoc-Val-OSu, 98%, Fmoc-amino acids 2,5-dioxopyrrolidin-1-yl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanoate N-Fmoc-L-valineN-succinimidylester,95% Fmoc-L-valine-osu Trastuzumab Impurity 1 (Fmoc-Val-Osu) Fmoc-Val-0su 2,5-dioxopyrrolidin-1-yl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-valinate 130878-68-1 Fmoc-Amino Acids and Derivatives Fmoc-Amino acid series Amino Acids