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4-(Trifluoromethyl)phenacyl bromide

4-(Trifluoromethyl)phenacyl bromide structure

CAS No.: 383-53-9

Chemical Name:: 4-(Trifluoromethyl)phenacyl bromide

Synonyms: 2-BroMo-4&priMe;BUTTPARK 35\01-55;methyl 3-cyano-5-nitrobenzoate;4-TRIFLUOROMETHYLPHENACYL BROMIDE;4-(Trifluoromethyl)phecyl bromide;4'-(TRIFLUOROMETHYL)PHENACYL BROMIDE;4-(Trifluoromethyl)phenacylbromide97%;4-(Trifluoromethyl)phenacyl bromide 97%;2-Bromo-4'-(trifluoromethyl)acetophenon;2-Bromo-4'-(trifluoromethyl)acetophenone

CBNumber:: CB7782499

Molecular Formula:: C9H6BrF3O

Molecular Weight:: 267.04

MDL Number:: MFCD00126489

MOL File:: 383-53-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:06

Product description	Number	Pack Size	Price
2-Bromo-4′-(trifluoromethyl)acetophenone 95%	669466	1g	$28.5
2-Bromo-4′-(trifluoromethyl)acetophenone 95%	669466	5g	$57.5
2-Bromo-4'-(trifluoromethyl)acetophenone >95.0%(GC)	T2747	5g	$60
2-Bromo-4'-(trifluoromethyl)acetophenone >95.0%(GC)	T2747	25g	$249
2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one	B415118	500mg	$75

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4-(Trifluoromethyl)phenacyl bromide Properties

Melting point	45 °C
Boiling point	264.2±40.0 °C(Predicted)
Density	1.592±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	soluble in Methanol
form	powder to crystal
color	White to Yellow to Orange
InChI	1S/C9H6BrF3O/c10-5-8(14)6-1-3-7(4-2-6)9(11,12)13/h1-4H,5H2
InChIKey	HEMROKPXTCOASZ-UHFFFAOYSA-N
SMILES	FC(F)(F)c1ccc(cc1)C(=O)CBr
CAS DataBase Reference	383-53-9(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

C,Xi

Risk Statements

34-36/37/38

Safety Statements

26-36/37/39-45-36

RIDADR

1759

WGK Germany

HazardClass

CORROSIVE

PackingGroup

III

HS Code

29147000

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	0
2		0

4-(Trifluoromethyl)phenacyl bromide price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	669466	2-Bromo-4′-(trifluoromethyl)acetophenone 95%	383-53-9	1g	$28.5	2026-04-30	Buy
Sigma-Aldrich	669466	2-Bromo-4′-(trifluoromethyl)acetophenone 95%	383-53-9	5g	$57.5	2026-04-30	Buy
TCI Chemical	T2747	2-Bromo-4'-(trifluoromethyl)acetophenone >95.0%(GC)	383-53-9	5g	$60	2026-04-30	Buy
TCI Chemical	T2747	2-Bromo-4'-(trifluoromethyl)acetophenone >95.0%(GC)	383-53-9	25g	$249	2026-04-30	Buy
TRC	B415118	2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one	383-53-9	500mg	$75	2021-12-16	Buy

Product number	Packaging	Price	Buy
669466	1g	$28.5	Buy
669466	5g	$57.5	Buy
T2747	5g	$60	Buy
T2747	25g	$249	Buy
B415118	500mg	$75	Buy

4-(Trifluoromethyl)phenacyl bromide Chemical Properties,Uses,Production

Chemical Properties

White powder or crystal

Synthesis

1-(2-Bromoethynyl)-4-(trifluoromethyl)benzene

313343-88-3

383-53-9

General procedure for the synthesis of 2-bromo-4'-(trifluoromethyl)acetophenone using 1-(bromoethynyl)-4-(trifluoromethyl)benzene as starting material: a mixed solution of haloalkynes (0.5 mmol), silver fluoride (5 mol%), and water (1 eq.) in trifluoroacetic acid (1 mL) was stirred for 6 hours at 40 °C. Upon completion of the reaction, the trifluoroacetic acid was recovered by distillation for reuse. The residue was purified by column chromatographic separation to afford the target product 2-bromo-4'-(trifluoromethyl)acetophenone.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 7, p. 1373 - 1375
[2] European Journal of Organic Chemistry, 2016, vol. 2016, # 1, p. 116 - 121
[3] Tetrahedron, 2016, vol. 72, # 27-28, p. 3818 - 3822
[4] Tetrahedron Letters, 2016, vol. 57, # 45, p. 4983 - 4986
[5] Chinese Journal of Chemistry, 2016, vol. 34, # 12, p. 1251 - 1254

4-(Trifluoromethyl)phenacyl bromide synthesis

Synthesis of 4-(Trifluoromethyl)phenacyl bromide from 4'-(Trifluoromethyl)acetophenone

4-(Trifluoromethyl)phenacyl bromide Preparation Products And Raw materials

Raw materials

1,4-Dioxane Diethyl ether Bromine 4'-(Trifluoromethyl)acetophenone 1-(2-Bromoethynyl)-4-(trifluoromethyl)benzene

4'-TRIFLUOROMETHYLPHENYL ACETYLENE Ethanediol AR 500ML 4-(TRIFLUOROMETHYL)STYRENE

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Preparation Products

1,3-Dioxolane, 2-(bromomethyl)-2-[4-(trifluoromethyl)phenyl]- 2-Oxazoleethanol, β,5-dibromo-4-[4-(trifluoromethyl)phenyl]-, 2-acetate 1H-Isoindole-1,3(2H)-dione, 2-[2-oxo-2-[4-(trifluoromethyl)phenyl]ethyl]- 2-(4-(trifluoromethyl)phenyl)imidazo[1,2-a]pyrimidine 2-(Methylsulfanyl)-1-[4-(trifluoromethyl)phenyl]ethan-1-one

4-(Trifluoromethyl)phenacyl bromide Suppliers

Global( 149)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Changzhou Ansciep Chemical Co., Ltd.	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Fuxin Pharmaceutical	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 4-(Trifluoromethyl)phenacyl bromide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-30	4-(Trifluoromethyl)phenacyl bromide 383-53-9	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2022-02-22	4-(Trifluoromethyl)phenacyl bromide 383-53-9	US $0.00 / KG	1KG	97.7%	100 tons	Honest Joy Holdings Limited
2019-12-23	4-(Trifluoromethyl)phenacyl bromide 383-53-9	US $1.00 / KG	1g	85.0-99.8%	20ton	Career Henan Chemical Co

4-(Trifluoromethyl)phenacyl bromide
383-53-9
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4-(Trifluoromethyl)phenacyl bromide
383-53-9
US $0.00 / KG
97.7%
Honest Joy Holdings Limited

4-(Trifluoromethyl)phenacyl bromide
383-53-9
US $1.00 / KG
85.0-99.8%
Career Henan Chemical Co

4-(Trifluoromethyl)phenacyl bromide Spectrum

4-(Trifluoromethyl)phenacyl bromide(383-53-9)¹HNMR

383-53-9(4-(Trifluoromethyl)phenacyl bromide)Related Search:

4'-(Trifluoromethyl)acetophenone 2-FLUORO-4-(TRIFLUOROMETHYL)PHENACYL BROMIDE 2-BROMO-2',6'-DICHLORO-4'-(TRIFLUOROMETHYL)-ACETOPHENONE 4-(Trifluoromethyl)phenacyl bromide 2,3-DIFLUORO-4-(TRIFLUOROMETHYL)PHENACYL BROMIDE

2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE ETHYL 2-BROMO-3-(4-TRIFLUOROMETHYLPHENYL)-3-OXO-PROPANOATE 3-FLUORO-4-(TRIFLUOROMETHYL)PHENACYL BROMIDE 2-BROMO-1-(4-TRIFLUOROMETHYL-PHENYL)-PENTAN-1-ONE

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2-broMo-1-(4-(trifluoroMethyl)phenyl)ethanone BUTTPARK 35\01-55 2-Bromo-4'-(trifluoromethyl)acetophenone, 2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one 4'-(TRIFLUOROMETHYL)PHENACYL BROMIDE 4-TRIFLUOROMETHYLPHENACYL BROMIDE 2-BROMO-1-[4-(TRIFLUOROMETHYL)PHENYL]-1-ETHANONE 2-BROMO-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHAN-1-ONE 2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one, tech 4-(Trifluoromethyl)phenacyl bromide 97% 4-(Trifluoromethyl)phenacylbromide97% 4-(TRIFLUOROMETHYL)PHENACYL BROMIDE: TECH. 2-Bromo-4'-(trifluoromethyl)acetophenon methyl 3-cyano-5-nitrobenzoate 2-BroMo-4&priMe 4-(Trifluoromethyl)phecyl bromide Ethanone, 2-bromo-1-[4-(trifluoromethyl)phenyl]- 2-Bromo-4'-(trifluoromethyl)acetophenone 2-Bromo-4′-(trifluoromethyl)acetophenone, CAS 383-53-9 383-53-9 C9H6BrF3O Building Blocks Carbonyl Compounds C9 Ketones Organic Building Blocks Benzene series