SR 11302
- CAS No.
- 160162-42-5
- Chemical Name:
- SR 11302
- Synonyms
- SR 11302;RQANARBNMTXCDM-DKOHIBGUSA-N;(2E,4E,6Z,8E)-3-Methyl-7-(p-tolyl)-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;(E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoicacid;2,4,6,8-Nonatetraenoic acid, 3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (2E,4E,6Z,8E)-;acid,SR11302,retinoid,SR-11302,Lung,RARE,Cancer,response,Inhibitor,protein-1,SR 11302,inhibit,AP-1,retinoic,element,activator
- CBNumber:
- CB7844692
- Molecular Formula:
- C26H32O2
- Molecular Weight:
- 376.53
- MDL Number:
- MFCD09038562
- MOL File:
- 160162-42-5.mol
SR 11302 price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16338 | SR 11302 ≥95% | 160162-42-5 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 16338 | SR 11302 ≥95% | 160162-42-5 | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 16338 | SR 11302 ≥95% | 160162-42-5 | 10mg | $235 | 2024-03-01 | Buy |
| Cayman Chemical | 16338 | SR 11302 ≥95% | 160162-42-5 | 25mg | $479 | 2024-03-01 | Buy |
| Tocris | 2476 | SR11302 ≥98%(HPLC) | 160162-42-5 | 10 | $231 | 2021-12-16 | Buy |
SR 11302 Chemical Properties,Uses,Production
Description
The receptors for retinoids, RARs and RXRs, induce transcriptional activation by binding the specific retinoid response elements, RARE and RXRE. Alternatively, retinoid receptors interact with and modulate other transcription factors, including activator protein-1 (AP-1). SR 11302 is a synthetic retinoid that inhibits AP-1 activity without activating transcription through RARE. It significantly suppresses both AP-1 activation and phorbol ester-induced papilloma formation in mice when applied topically (0.1 μM). SR 11302 is used to elucidate the role of AP-1 in various signaling pathways.
Uses
SR 11302 is an inhibitor of activator protein-1.
Biological Activity
Inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumor effects in vivo . Does not activate transcription from the retinoic acid response element (RARE) and displays no activity at retinoic acid receptors (EC 50 > 1 μ M for RAR α , RAR β , RAR γ and RXR α ).
storage
Store at -20°C
SR 11302 Preparation Products And Raw materials
Raw materials
Preparation Products
SR 11302 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19185 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3419 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |