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DEVAZEPIDE

CAS No.
103420-77-5
Chemical Name:
DEVAZEPIDE
Synonyms
718;MK-329;L-364718;evazepide;DEVAZEPIDE;EVAZEPIDE, PANOS;Betaxolol Impurity 12;(3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one;(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide;N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE
CBNumber:
CB7849798
Molecular Formula:
C25H20N4O2
Molecular Weight:
408.45
MDL Number:
MFCD00864500
MOL File:
103420-77-5.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

DEVAZEPIDE Properties

Boiling point 758.6±60.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >5mg/mL
pka 13.25±0.40(Predicted)
form powder
color white to off-white
FDA UNII JE6P7QY7NH

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P264-P301+P310
Hazard Codes  T+
Risk Statements  28
Safety Statements  28-36/37-45
RIDADR  UN 2811 6.1 / PGI
WGK Germany  3
RTECS  NL5994460

DEVAZEPIDE price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D3821 Devazepide ≥98% (HPLC), powder 103420-77-5 5mg $123.6 2024-03-01 Buy
Sigma-Aldrich D3821 Devazepide ≥98% (HPLC), powder 103420-77-5 25mg $825 2024-03-01 Buy
Tocris 2304 Devazepide ≥99%(HPLC) 103420-77-5 50 $1135 2021-12-16 Buy
Tocris 2304 Devazepide ≥99%(HPLC) 103420-77-5 10 $270 2021-12-16 Buy
Usbiological 255128 Devazepide 103420-77-5 10mg $531 2021-12-16 Buy
Product number Packaging Price Buy
D3821 5mg $123.6 Buy
D3821 25mg $825 Buy
2304 50 $1135 Buy
2304 10 $270 Buy
255128 10mg $531 Buy

DEVAZEPIDE Chemical Properties,Uses,Production

Uses

Antagonist (cholecystokinin).

Uses

Devazepide has been used as a cholecystokinin receptor 1 (CCK1R) antagonist in human embryonic kidney 293T cells and in human pancreatic slices.

Definition

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f r treatment of gastrointestinal disorders.

General Description

Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.

Biochem/physiol Actions

Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.

storage

Store at +4°C

DEVAZEPIDE Preparation Products And Raw materials

Raw materials

Preparation Products

DEVAZEPIDE Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613 sales@chemrenpharm.com China 3538 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd 1701086315 dexuanpharma@126.com China 9478 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE DEVAZEPIDE EVAZEPIDE, PANOS (3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one L-364718 MK-329 (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide 1H-Indole-2-carboxamide, N-[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]- 718 evazepide Betaxolol Impurity 12 103420-77-5 C25H20N4O2