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Phenylacetyl chloride

Phenylacetyl chloride
Phenylacetyl chloride structure
Chemical Name:
Phenylacetyl chloride
phenylacetyl;-Toluylchloride;A-TOLUYL CHLORIDE;AKOS BBS-00003909;ylacetyl chloride;PHENACETYL CHLORIDE;Phenyl acetyl chlori;henylacetyl chloride;alpha-Toluyl chloride;PHENYLACETYL CHLORIDE
Molecular Formula:
Formula Weight:
MOL File:

Phenylacetyl chloride Properties

Melting point:
264-266 °C(Solv: N,N-dimethylformamide (68-12-2))
Boiling point:
94-95 °C/12 mmHg (lit.)
1.169 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.5325(lit.)
Flash point:
217 °F
storage temp. 
Miscible with alcohol and ether.
Moisture Sensitive
Stable. Reacts with water. Incompatible with amines, most common metals, moisture, strong oxidizing agents.
CAS DataBase Reference
103-80-0(CAS DataBase Reference)
NIST Chemistry Reference
Benzeneacetyl chloride(103-80-0)
EPA Substance Registry System
Benzeneacetyl chloride (103-80-0)
  • Risk and Safety Statements
Signal word  Danger
Hazard statements  H318-H314-H335
Precautionary statements  P261-P280-P305+P351+P338-P310-P260h-P301+P330+P331-P303+P361+P353-P405-P501a
Hazard Codes  C
Risk Statements  34-37-14
Safety Statements  26-36/37/39-45-25-27
RIDADR  UN 2577 8/PG 2
WGK Germany  3
HazardClass  8
PackingGroup  II
HS Code  29163900

Phenylacetyl chloride price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P16753 Phenylacetyl chloride 98% 103-80-0 5g $25.4 2021-12-16 Buy
Sigma-Aldrich P16753 Phenylacetyl chloride 98% 103-80-0 100g $43.6 2021-12-16 Buy
TCI Chemical P0129 Phenylacetyl Chloride >98.0%(GC)(T) 103-80-0 25g $21 2021-12-16 Buy
TCI Chemical P0129 Phenylacetyl Chloride >98.0%(GC)(T) 103-80-0 100g $41 2021-12-16 Buy
Alfa Aesar B24987 Phenylacetyl chloride, 98% 103-80-0 100g $40.5 2021-12-16 Buy

Phenylacetyl chloride Chemical Properties,Uses,Production

Chemical Properties

colourless liquid


Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.

Synthesis Reference(s)

Journal of the American Chemical Society, 96, p. 6469, 1974 DOI: 10.1021/ja00827a034
Organic Syntheses, Coll. Vol. 2, p. 156, 1943

General Description

A colorless volatile liquid with a strong odor. Denser than water. Contact may severely irritate skin, eyes and mucous membranes. May be toxic by ingestion. May also be combustible.

Air & Water Reactions

Soluble in water. Fumes in air. Decomposes in water or steam to form very corrosive hydrogen chloride gas.

Reactivity Profile

Phenylacetyl chloride is incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Phenylacetyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

Phenylacetyl chloride Suppliers

Global( 253)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-66670886 China 15421 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 China 22607 55
Shanghai Time Chemicals CO., Ltd.
+8618017249410 +86-021-57951555
+86-021-57951555 China 1807 55
career henan chemical co
+86-0371-55982848 China 29953 58
+86 18953170293
+86 0531-67809011 CHINA 2940 58
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 China 5941 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114 CHINA 6369 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23035 58
Changzhou Carman Chemical Co., Ltd.
15061933924; CHINA 514 58

View Lastest Price from Phenylacetyl chloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-26 Phenylacetyl chloride
US $19.00 / KG 1KG 99% 29 Hong Kong Tiansheng New Material Trading Co., Ltd
2021-07-13 Phenylacetyl chloride
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09 Phenylacetyl chloride
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

Phenylacetyl chloride Spectrum

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