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Physical and chemical properties The main purpose and effect Chemical additives Harmful effects and symptoms of poisoning Uses Production method Category Toxicity grading Acute toxicity Stimulus data Flammability hazard characteristics Storage Characteristics Extinguishing agent Occupational standards
Pentaerythritol structure
Chemical Name:
PETP;THME;PE-T;PE-M;JWSC;pe200;PE 200;Pentek;PE-C-N;Penetek
Molecular Formula:
Formula Weight:
MOL File:

Pentaerythritol Properties

Melting point:
253-258 °C (lit.)
Boiling point:
276 °C/30 mmHg (lit.)
vapor pressure 
<1 mm Hg ( 20 °C)
refractive index 
Flash point:
240 °C
storage temp. 
Store below +30°C.
H2O: 0.1 g/mL, clear, colorless
3.5-4.5 (100g/l, H2O, 35℃)
Water Solubility 
1 g/18 mL (15 ºC)
Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides. Combustible.
CAS DataBase Reference
115-77-5(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances
175.105; 175.300; 175.320
EWG's Food Scores
NIST Chemistry Reference
1,3-Propanediol, 2,2-bis(hydroxymethyl)-(115-77-5)
EPA Substance Registry System
Pentaerythritol (115-77-5)
  • Risk and Safety Statements
Risk Statements  33
Safety Statements  24/25
WGK Germany  1
RTECS  RZ2490000
Autoignition Temperature 490 °C
HS Code  29054200
Toxicity LD50 orally in Rabbit: > 5110 mg/kg LD50 dermal Rabbit > 10000 mg/kg

Pentaerythritol price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P4755 Pentaerythritol 98% 115-77-5 500 g $23.3 2021-03-22 Buy
Sigma-Aldrich 8.07331 Pentaerythritol for synthesis 115-77-5 100 g $29.69 2021-03-22 Buy
Sigma-Aldrich P4755 Pentaerythritol 98% 115-77-5 1kg-a $35.2 2020-08-18 Buy
Sigma-Aldrich P4755 Pentaerythritol 98% 115-77-5 1 kg $36 2021-03-22 Buy
Sigma-Aldrich 8.07331 Pentaerythritol for synthesis 115-77-5 1 kg $49.12 2021-03-22 Buy

Pentaerythritol Chemical Properties,Uses,Production

Physical and chemical properties

Pentaerythritol is also called 2, 2-double (hydroxymethyl)-1, 3-propanediol, four hydroxymethyl methane, MetabAuxil, Penetek. White crystal powder. It was first found in 1882 by Tollens, and is colorless tetragonal crystal double tetrahedral crystal precipitated from dilute hydrochloric acid. The relative molecular mass is 136.15. Relative density is 1.399. Melting point is 262 oC (industrial products containing 10%~15% Dipentaerythritol, melting point is 180~225 oC). The boiling point is 276 oC (4.00 x 103 pa). The refractive index is 1.54~1.56. Can sublimate. Slowly soluble in cold water, soluble in hot water, insoluble in carbon tetrachloride, ethyl ether, benzene, petroleum ether, ethanol, acetone, solubility at 25 oC (g/100 g) in water, methanol, ethanol, butylamine, dimethyl sulfoxide, ethanolamine are 0.75, 7.23, 0.33, 16, 16.5 4.5, respectively. 1 g of dipentaerythritol can soluble in 18 ml of water at 15 oC. Pentaerythritol will polymerize when heated to above melting point, and generates a shrinkage second shrinkage e four season three pentaerythritol, etc. Stability in the air. The hydroxyl groups of Pentaerythritol can form complex with many kinds of metal; Can directly react with nitric acid trough nitration; Under the effect of catalyst, the hydroxy can be oxidized to acid; Can react with chlorine to generate the chloride; In acid medium, the product react with carbonyl compounds, generate cyclic acetal and ketal; Like other alcohols, can esterify with an acid or anhydride to generate four ester; The halides can dehalogenate to generate cyclic ether in the role of alkali. The addition reaction intermediate of 3-hydroxy aldehyde can react with formaldehyde through Cannizzaro reaction to generate season four amyl alcohol and formic acid. In 1938, it was first generated by United States with acetaldehyde and five times the amount of formaldehyde in the reaction of calcium hydroxide solution system. It is the only production method used in the industrial. Main purpose is to make explosives and synthetic resin (mainly used for various coatings).

The main purpose and effect

As quaternary alcohol, pentaerythritol is easily generated by esterification acid and ester, so most of the classes used in alkyd resin coatings raw materials, mainly used for architectural coatings and automotive primer. Pentaerythritol is used to esterification with nitric acid to generate pentaerythritol tetranitrate (also known as PETN) in 5~15 oC in industrial, which is a kind of high explosives and bigger than TNT explosive, most as a booster, or mix with TNT. A lot of PETN have been used in the second world war. PETN has the effect of diastolic blood vessels, is a long-term vasodilator and can treat angina pectoris. Pentaerythritol reaction with rosin acid can produce rosin pentaerythritol ester, which can be mixed with drying oil and is a kind of coating with better hardness, water resistance and weather resistance, can be used in ink of varnish, floor, etc. By esterification condensation pentaerythritol or glycerol with phthalic anhydride, fatty acid can make an alkyd resin coating. Use of different kinds and different amount of fatty acid can improve the properties of alkyd resin, making it a suitable coating of various kinds in need. It is widely used as a coating on the surface of the metal, wood, as a bridge, railway, derrick, building and other aspects of commonly used industrial paint and architectural paint. Because of the price is low, alkyd resin of reactants, easy modification, strong adaptability, good comprehensive, it has become the backbone of the coating industry since 1927.
Pentaerythritol is often used in coating industry, is of alkyd coating raw material for the production of highly cross linked coatin using four hydroxyls, the coating has good hardness and color, can improve the hardness, luster and durability of the coating film. Used as varnish, paint and ink production of rosin ester raw material, and can be used as flame retardants, drying oil, aviation lubricating oil. Pentaerythritol fatty acid ester is polyvinyl chloride (PVC), plasticizer and stabilizer is also used in medicine, pesticide, lube oil manufacture.
Pentaerythritol acrylic ester generated by Pentaerythritol and acrylic acid has a fast drying property, it is widely used in radiation-curing coatings and quick drying of printing ink, water soluble alkyd resin, the polymer can be used as adhesive. The C6~C10 fatty acid ester of Pentaerythritol are mainly used as advanced lubricant for steam turbine, automobile engine etc. The ester produced by this product with C10~C12 fatty acid, can be used as a plastic plasticizer, which has low volatility and high ageing resistance; Reaction with epoxy compound, and its product can be used as a surface active agent, widely used in detergent and cosmetics and perfume raw materials; This product is used as the material of explosives, medicine, pesticides, organic intermediates, etc.
The above information is edited by the Chemicalbook of Duan Yalan.

Chemical additives

Pentaerythritol can be used as a stabilizing agent, and has synergistic effect with zinc salt stabilizers, can replace allyl chloride to stabilize PVC. General dosage is half serving. But the compatibility with the resin of this product is small, easy to bloom, and soluble in water, easy sublimation, easy deposit on processing equipment and interfere with the processing in the process of sublimation.

Harmful effects and symptoms of poisoning

Pentaerythritol has low toxicity, from rat infected through the mouth to the dose of 40 g/kg body weight, no obvious toxic symptoms. The US Food and Drug Administration permits it for food packaging materials (FDA121.2566), the highest dosage is 0.4%.
Someone reports and food studies showed that 85% of pentaerythritol were discharged from the urine after oral within 30 h. Generally speaking, according to the usual route of exposure even under abnormal use concentration, no significant effect to health.


It is mainly used in alkyd resin production, also used for manufacturing ink, lubricants, plasticizer, surface active agent, explosives and drugs raw materials.
Used as a resin and synthetic fiber antistatic agent, solvent conditioner, oil, etc.
Pentaerythritol is mainly used in the coating industry, is the source of alkyd resin coating, can make the coating film hardness, gloss, with improved durability, it is used as varnish, color paint and printing ink of pine resin needed raw materials, and with smoldering sex coating, drying oil and matter could be empty lubricating oil and so on. Pentaerythritol tetranitrate is a kind of high explosives (taian); The fatty acid ester is an efficient lubricant and PVC plasticizer; The epoxide production is the raw material from the raw surface active agent, pentaerythritol easy forms authority complex with metal, also as hard water softener used in detergent formulation, in addition, it can also be used in medicine, pesticide and other production.
Gas chromatographic stationary liquid [highest use temperature 150 ℃, the solvent of chloroform + butyl alcohol (1:1)], separation and analysis of low boiling point oxygen-containing compounds, amine compounds, nitrogen or oxygen heterocyclic compounds. Organic synthesis, preparation, resin synthesized polyols.

Production method

It is produced using formaldehyde and acetaldehyde as raw materials, in the presence of alkaline condensation agent reaction. When using sodium hydroxide as condensing agent, it is called sodium method. The molar ratio of raw materials for acetaldehyde: formaldehyde: alkali is 1.5: 6: 1.1-1.3. Adding sodium hydroxide solution to 37% formaldehyde solution, join the acetaldehyde under stirring at 25-32 oC and react for 6 to 7 h. By the neutralization filter to obtain pentaerythritol. Raw material consumption quota: formaldehyde (37%) 2880 kg/t, acetaldehyde 350 kg/t. When using calcium hydroxide as a condensing agent, it is called calcium method. The molar ratio of raw materials for acetaldehyde: formaldehyde: lime is 1: 4.7: 0.7-0.8. Add the formaldehyde solution, 20% acetaldehyde solution and 25% lime milk to reaction pot, react at 60 oC, condensate until liquid color turned to blue from gray. Gradually cooled to 45 oC in the acidification of pan. Acidificate the condensed liquid with 60-70% of the sulfuric acid to the pH of 2-2.5, then use filter airland to calcium sulfate. Filtrate through ion exchange column to remove residual calcium ion, stress concentration, keep gas temperature under 70 oC, vacuum at 77.3 kPa. Began to crystallize, transfer concentrate in the crystallizer, mixing the cooling crystallization, centrifugal separation, washed with water to the pH of 3, drying by the airflow then obtain products. The consumption of Calcium method is high, and also has the problem of "three wastes". Raw material consumption quota: formaldehyde (36.5%) 4700 kg/t, acetaldehyde 550 kg/t.


Flammable fluid.

Toxicity grading


Acute toxicity

Oral-LD50 in rats: 12600 mg/kg. Oral LD50 in mice: 4097 mg/kg.

Stimulus data

Skin-rabbit 500 mg/24 hours light; Eyes-rabbit 126 mg light.

Flammability hazard characteristics

Flammable. Combustion produces stimulation of smoke.

Storage Characteristics

Warehouse ventilation, dry at low temperature.

Extinguishing agent

Dry powder, foam, sandy soil, and water.

Occupational standards

The TLV-TWA 10 mg/cubic meter.

Chemical Properties

Pentaerythritol is a white crystalline solid. Odorless.


In the manufacture of pentaerythritol tetranitrate; alkyd resins in surface-coating compositions; pentaerythritol triacrylate and protective coatings; insecticides; pharmaceuticals


pentaerythritol: white crystallinecompound, C(CH2OH)4; m.p.260°C; b.p. 276°C (30 mmHg). It isused in making the explosive pentaerythritoltrinitrate and in producingresins and other organicproducts.

General Description

Odorless white solid. Sinks and mixes slowly with water.

Air & Water Reactions

Water soluble.

Reactivity Profile

Pentaerythritol is an alcohol. Pentaerythritol is incompatible with the following: Organic acids, oxidizers [Note: Explosive compound is formed when a mixture of PE & thiophosphoryl chloride is heated.] .

Health Hazard

Non-toxic; no symptoms likely

Safety Profile

Mildly toxic by ingestion. A nuisance dust. Flammable from heat or flame or oxidizers. Wxtures with thiophosphoryl chloride react when heated to form a product that ignites and then explodes on contact with air. Used in coatings, stabdizers, explosives, P.E.T.N resins, drugs, insecticides, and lubricants When heated to decomposition it emits acrid smoke and irritating fumes

Potential Exposure

Pentaerythritol is used in coatings and stabilizers; in the formation of alkyd resins and varnishes. It is used as an intermediate in the manufacture of plasticizers, explosives (PETN),and pharmaceuticals.


UN1987 Alcohols, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

Reflux pentaerythritol with an equal volume of MeOH, then cool, and the precipitate is collected and dried at 90o. It can also be crystallised from dilute aqueous HCl. After sublimation under high vacuum at 200o it has m 265.5o. Its solubility in H2O is 10%. [Beilstein 18 III 2361, 1 IV 2812.]


Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong acids, organic acids, strong bases. Aquesous solution is acidic. Explosive compound is formed when a mixture of Pentaerythritol and thiophosphoryl chloride (CAS 3892-91-0) is heated.

Pentaerythritol Preparation Products And Raw materials

Raw materials

Preparation Products

Pentaerythritol Suppliers

Global( 327)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418697 China 3000 55
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 CHINA 1817 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
+86-571-56059825 CHINA 8909 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 CHINA 3623 58
career henan chemical co
+86-371-86658258 CHINA 29954 58
+86 18953170293
+86 0531-67809011 CHINA 2941 58
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 China 5892 58
hdzhl biotechnology co., ltd
86-13032617415 CHINA 1275 58

View Lastest Price from Pentaerythritol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-11-08 Pentaerythritol
US $10.00 / KG 1KG 99% 20 tons Wuhan wingroup Pharmaceutical Co., Ltd
2021-07-09 pentaerythritol
US $2.00 / KG 1KG 98% 2000 Metric Ton/Metric Tons per Month Hebei Xibaijie Biotechnology Co., Ltd.
2021-04-07 Pentaerythritol
US $10.00 / PCS 1KG 99% 100 mt Hebei Guanlang Biotechnology Co., Ltd.

Pentaerythritol Spectrum

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