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(R)-(-)-2-Amino-1-propanol

(R)-(-)-2-Amino-1-propanol structure

CAS No.: 35320-23-1

Chemical Name:: (R)-(-)-2-Amino-1-propanol

Synonyms: (R)-1-Aminopropan-2-ol;D-ALANINOL;(R)-2-AMINO-1-PROPANOL;(2R)-2-AMINO-1-PROPANOL;D-ALAOH;2-AMINO PROPANOL;(2R)-2-Aminopropan-1-ol;D-Ala-ol;D-Alaniol;H-D-ALA-OL

CBNumber:: CB7853542

Molecular Formula:: C3H9NO

Molecular Weight:: 75.11

MDL Number:: MFCD00064413

MOL File:: 35320-23-1.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
(R)-(?)-2-Amino-1-propanol 98%	297682	1g	$25.92
(R)-(?)-2-Amino-1-propanol 98%	297682	5g	$132
(R)-(-)-2-Amino-1-propanol >98.0%(GC)(T)	A2002	5mL	$86
(R)-(-)-2-Amino-1-propanol >98.0%(GC)(T)	A2002	25mL	$254
(R)-(-)-2-Amino-1-propanol	A628145	5G	$80
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(R)-(-)-2-Amino-1-propanol Properties

Melting point	8 °C
Boiling point	173-176 °C(lit.)
alpha	-17 º (c=neat)
Density	0.965
refractive index	n20/D 1.450(lit.)
Flash point	183 °F
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Oily Liquid
pka	12.88±0.10(Predicted)
Specific Gravity	0.965
color	Clear colorless to light yellow
optical activity	[α]19/D 18°, neat
Water Solubility	SOLUBLE
Sensitive	Hygroscopic
BRN	1718866
CAS DataBase Reference	35320-23-1(CAS DataBase Reference)
FDA UNII	770ZI70L3Q
NIST Chemistry Reference	(R)-(-)-2-Amino-1-propanol(35320-23-1)
UNSPSC Code	12352116
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405

Hazard Codes

C,Xi

Risk Statements

34-36/37/38

Safety Statements

26-36/37/39-45-36

RIDADR

UN 2735 8/PG 2

WGK Germany

10-23

Hazard Note

Corrosive/Hygroscopic

HazardClass

PackingGroup

III

HS Code

29221990

Limited Quantities

1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	2
3		0

(R)-(-)-2-Amino-1-propanol price More Price(48)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	297682	(R)-(?)-2-Amino-1-propanol 98%	35320-23-1	1g	$25.92	2024-03-01	Buy
Sigma-Aldrich	297682	(R)-(?)-2-Amino-1-propanol 98%	35320-23-1	5g	$132	2023-06-20	Buy
TCI Chemical	A2002	(R)-(-)-2-Amino-1-propanol >98.0%(GC)(T)	35320-23-1	5mL	$86	2025-07-31	Buy
TCI Chemical	A2002	(R)-(-)-2-Amino-1-propanol >98.0%(GC)(T)	35320-23-1	25mL	$254	2025-07-31	Buy
TRC	A628145	(R)-(-)-2-Amino-1-propanol	35320-23-1	5G	$80	2021-12-16	Buy

Product number	Packaging	Price	Buy
297682	1g	$25.92	Buy
297682	5g	$132	Buy
A2002	5mL	$86	Buy
A2002	25mL	$254	Buy
A628145	5G	$80	Buy

(R)-(-)-2-Amino-1-propanol Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(-)-2-Amino-1-propanol has been used as a derivatizing agent for gossypol during the analysis of gossypol enantiomers in cottonseed by high-performance liquid chromatography.

Application

R)-(-)-2-Amino-1-propanol is used as a chiral intermediate for the synthesis of pharmaceutical products and agrochemicals. It acts as additives in health care products and animal feed. It is a amino alcohol obtained by reduction of d-alanine. This compound could be converted into the corresponding nonracemic adenine derivative (R)-9-(1-Methyl-2-hydroxyethyl)adenine through minor variations on the classic Montgomery sequence[1].
(R)-(-)-2-Amino-1-propanol

General Description

(R)-(-)-2-Amino-1-propanol is a chiral secondary amine.

Synthesis

338-69-2

35320-23-1

General procedure for the synthesis of (R)-2-aminopropan-1-ol from D-alanine: The present embodiment relates to the synthesis of a class of intermediates of long-chain ethylpiperazine sulfonamide derivatives, in particular the preparation of (R)-2-aminopropan-1-ol. 150 mL of anhydrous THF and 1.1 g of LiAlH4 (29 mmol) were added to a dry three-necked flask and the reaction system was cooled to 0 °C. Subsequently, 4.9 g of D-alanine (55.0 mmol) was added to the reactor in batches, and the addition process lasted for 30 min. After the addition was completed, stirring was continued at 0 °C for 2 h. Then the temperature was gradually increased to reflux and the reflux reaction was maintained for 16 h. The reaction system was then cooled to 0 °C for 2 h. Upon completion of the reaction, the reaction system was cooled in an ice bath, and 100 mL of ether, 4.5 mL of water, 4.5 mL of 15% NaOH solution, and 12 mL of water were added slowly in sequence to quench the reaction. The reaction mixture was filtered through diatomaceous earth and the filtrate was collected. The filtrate was concentrated under reduced pressure to remove the solvent to give the crude product. The crude product was purified by silica gel column chromatography with the eluent of dichloromethane:ethanol=10:1 (v/v), resulting in 3.41 g of colorless oily product in 82.5% yield.

References

[1] Jeffery A, et al. Synthesis of Acyclic Nucleoside and Nucleotide Analogues from Amino Acids: A Convenient Approach to a PMEA±PMPA Hybrid. Tetrahedron, 2000; 56: 5077-5083.

(R)-(-)-2-Amino-1-propanol Preparation Products And Raw materials

Raw materials

methyl DL-alaninate D-Alanine Propylene glycol Lithium Aluminum Hydride Tetrahydrofuran

Preparation Products

Carbamic acid, N-[(1R)-2-hydroxy-1-methylethyl]-, 2-propen-1-yl ester N-(2-HYDROXY-1R-METHYLETHYL)-HEXADECANAMIDE

(R)-(-)-2-Amino-1-propanol Suppliers

Global( 546)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang Brunova Technology Co., Ltd.	8617857108485 17857108485	info@zjbrunova.com	China	48	58
Jinan Dexinjia Bio&Tech Co., Ltd	+86-0531-82375818 +86-15064153060	sales@jndxj.com	China	1371	58
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD	+8613572219112	info@pushanshiye.com	China	165	58
JiangXi Bobert Imp&Exp Co.,LTD	+8618071643627	rze2024@163.com	China	226	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8770	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	+8613288715578	sales@sichuanzyyt.com	China	12217	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20171	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21614	55

Supplier	Advantage
Zhejiang Brunova Technology Co., Ltd.	58
Jinan Dexinjia Bio&Tech Co., Ltd	58
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD	58
JiangXi Bobert Imp&Exp Co.,LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55

Application research of (D)-2-alaninol
(D)-2-Alaninol is one of the raw materials for synthesizing the ofloxacin. This article will introduce other application resea....
Jul 24，2025

View Lastest Price from (R)-(-)-2-Amino-1-propanol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-14	(R)-(-)-2-Amino-1-propanol 35320-23-1	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-09-25	(R)-(-)-2-Amino-1-propanol 35320-23-1	US $34.00-1.20 / kg	1kg	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2025-08-08	(R)-(-)-2-Amino-1-propanol 35320-23-1	US $0.00 / KG	1KG	99%	50000KG/month	Sichuan Zhuoyu Yantang Technology Co., Ltd.

(R)-(-)-2-Amino-1-propanol
35320-23-1
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

(R)-(-)-2-Amino-1-propanol
35320-23-1
US $34.00-1.20 / kg
99%
Henan Fengda Chemical Co., Ltd

(R)-(-)-2-Amino-1-propanol
35320-23-1
US $0.00 / KG
99%
Sichuan Zhuoyu Yantang Technology Co., Ltd.

(R)-(-)-2-Amino-1-propanol Spectrum

(R)-(-)-2-Amino-1-propanol(35320-23-1)MS (R)-(-)-2-Amino-1-propanol(35320-23-1)¹HNMR (R)-(-)-2-Amino-1-propanol(35320-23-1)¹³CNMR (R)-(-)-2-Amino-1-propanol(35320-23-1)IR1 (R)-(-)-2-Amino-1-propanol(35320-23-1)Raman

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D-Alaninol, 98%, ee: 98% (R)-(-)-2-AMINOPROPANOL (R)-(-)-2-AMINO-1-PROPANOL H-D-ALA-OL H-D-ALANINOL H-DL-ALA-OL D-(-)-ALANINOL D-2-AMINO-PROPANOL D-Alaninol, ee: 97% D - aMino propanol (R)-(-)-2-Amino-1-propanol (R)-(-)-2-AMino-1-propanol 98% (R)-(-)-2-AMino-1-propanol, 99.8%+ D-Alaninol≥ 99% (GC) (+/-)-2-AMINO-1-PROPANOL DL-2-AMINOPROPYL-ALCOHOL DL-2-AMINO PROPANOL DL-ALANILOL D-ALANINOL / (R)-(-)-2-AMINO-1-PROPANOL D-amine propionic acid D-Alaniol-(R)-(-)-2-Amino-1-Propanol D-Alaniol R(-)-2-AMINO-1-PROPANOL-13C3 (D-ALANINOL D-Alaninol98% D-Ala-ol 1-PROPANOL, 2-AMINO-, (2R)- D-Alaninol ,98% [ee: 97%] D-Alanilol (2R)-2-Amino-1-hydroxypropane, D-Alaninol [(R)-1-Methyl-2-hydroxyethyl]amine (R)-(-)-2-Amino-1-propanol,98% (R)-(-)-2-Amino-1-propanol > (R)-(-)-2-Amino-1-propanol USP/EP/BP (R)-2-AMINO-1-PROPANOL D-ALAOH D-ALANINOL (2R)-2-AMINO-1-PROPANOL 2-AMINO PROPANOL (R)-1-Aminopropan-2-ol (2R)-2-Aminopropan-1-ol D-Alaninol, 98% [(R)-(-)-2-Amino-1-propanol] (D)-2-Alaninol 35320-23-1 5320-23-1 CH3CHNH2CH2OH AMINE Amino Alcohols Alphabetical Listings Amino Acid Derivatives BioChemical Asymmetric Synthesis Chiral Building Blocks Specialty Synthesis Peptide Synthesis Stable Isotopes Organic Building Blocks Alanine [Ala, A] Amino Alcohols (Chiral)