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Neostigmine Methyl Sulfate

Neostigmine Methyl Sulfate
Neostigmine Methyl Sulfate structure
CAS No.
51-60-5
Chemical Name:
Neostigmine Methyl Sulfate
Synonyms
ar-32;sb-23;GD-65;Stiglyn;tl-1394;hodostin;proserin;CAS51-60-5;Vagotigmine;PROSTIGMINE
CBNumber:
CB7853724
Molecular Formula:
C12H19N2O2.CH3O4S
Formula Weight:
334.39
MOL File:
51-60-5.mol

Neostigmine Methyl Sulfate Properties

Melting point:
175-177 °C(lit.)
storage temp. 
−20°C
solubility 
H2O: 1 g/mL
form 
powder
color 
white
Water Solubility 
1g/10mL
Merck 
14,6464
CAS DataBase Reference
51-60-5(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS08,GHS06
Signal word  Danger
Hazard statements  H320-H300-H315-H319-H334-H335
Precautionary statements  P261-P284-P304+P340-P305+P351+P338-P342+P311-P264-P301+P310-P270-P301+P310+P330-P305+P351+P338+P337+P313-P405-P501
Hazard Codes  T+
Risk Statements  28-36/37/38-42/43-26/27/28
Safety Statements  36-45-36/37/39-28A
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  CY1225000
HazardClass  6.1(a)
PackingGroup  II
HS Code  29242990
Toxicity LD50 in mice (mg/kg): 0.16 i.v.; 0.42 s.c.; 7.5 orally, (Randall, Lehmann)

Neostigmine Methyl Sulfate price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N2126 Neostigmine methyl sulfate 51-60-5 1g $45.3 2019-12-02 Buy
Sigma-Aldrich 1460000 Neostigmine methyl sulfate United States Pharmacopeia (USP) Reference Standard 51-60-5 200mg $352.8 2019-12-02 Buy
TCI Chemical N0447 Neostigmine Methyl Sulfate >98.0%(N) 51-60-5 5g $108 2019-12-02 Buy
TCI Chemical N0447 Neostigmine Methyl Sulfate >98.0%(N) 51-60-5 25g $334 2019-12-02 Buy
Cayman Chemical 23501 Neostigmine (methyl sulfate) ≥98% 51-60-5 1g $43 2018-11-19 Buy

Neostigmine Methyl Sulfate Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Uses

Cholinergic; miotic; antidote (curare)

brand name

Prostigmine (ICN).

General Description

Neostigmine methylsulfate,(m-hydroxyphenyl)trimethylammonium methylsulfatedimethylcarbamate or the dimethylcarbamic ester of 3-hydroxyphenyltrimethylammoniummethylsulfate (Prostigminmethylsulfate), is a bitter, odorless, white, crystalline powder.It is very soluble in water and soluble in alcohol. Solutionsare stable and can be sterilized by boiling. The compound istoo hygroscopic for use in a solid form and thus is alwaysused as an injection. Aqueous solutions are neutral to litmus.

Clinical Use

The methylsulfate salt is used postoperatively as a urinarystimulant and in the diagnosis and treatment of myastheniagravis.

Purification Methods

Crystallise the sulfate from EtOH or Me2CO (m 143-144o). Its solubility in H2O is ~10%. [Beilstein 13 III 939.] (It is cholinergic and highly TOXIC.)

Neostigmine Methyl Sulfate Preparation Products And Raw materials

Raw materials

Preparation Products


Neostigmine Methyl Sulfate Suppliers

Global( 189)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21792 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22631 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30057 58
GIHI CHEMICALS CO.,LIMITED
08657186217390
sales@gihichemicals.com CHINA 309 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23978 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8721 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20114 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213
info@longyupharma.com CHINA 814 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35438 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47484 58

View Lastest Price from Neostigmine Methyl Sulfate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-12-27 Neostigmine Methyl Sulfate
51-60-5
US $0.10 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
2018-08-06 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate
51-60-5
US $2100.00 / KG 10G 99.6% cusomise career henan chemical co

Neostigmine Methyl Sulfate Spectrum


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