butropium bromide
- CAS No.
- 29025-14-7
- Chemical Name:
- butropium bromide
- Synonyms
- BHB;Coliopan;Butropan;Butropium;[3(S)-endo]-;butropium bromide;butoxybenzyl hyoscyamine;N-(Butoxybenzyl)hyoscyamine bromide;(p-Butoxybenzyl)hyoscyaminium bromide;1αH,5αH-Tropanium, 8-(p-butoxybenzyl)-3α-hydroxy-, bromide, (-)-tropate (8CI)
- CBNumber:
- CB7877900
- Molecular Formula:
- C28H38NO4.Br
- Molecular Weight:
- 532.515
- MDL Number:
- MFCD01741617
- MOL File:
- 29025-14-7.mol
| Melting point | 166-168oC |
|---|---|
| alpha | D20 -21.7° (c = 0.5 in water) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
| FDA UNII | R3K4503MV7 |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 in male mice (mg/kg): 1500 orally; 660 s.c.; 12.0 i.v. (Tanaka, Hashimoto, 1972) |
|---|
butropium bromide price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B690080 | ButropiumBromide | 29025-14-7 | 50mg | $1695 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19431 | Butropium bromide | 29025-14-7 | 10mg | $1990 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001796 | BUTROPIUM BROMIDE 95.00% | 29025-14-7 | 50MG | $2194.5 | 2021-12-16 | Buy |
| AK Scientific | 9472CC | Butropiumbromide | 29025-14-7 | 10mg | $2736 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001796 | BUTROPIUM BROMIDE 95.00% | 29025-14-7 | 5MG | $816.75 | 2021-12-16 | Buy |
butropium bromide Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Originator
Coliopan,Eisai,Japan,1974
Uses
Anticholinergic. Antispasmodic.
Definition
ChEBI: Butropium bromide is an organic bromide salt of butropium. It is a drug which suppresses spasm of smooth muscles of internal organs, inhibits gastric acid secretion and relieves abdominal pain. It is used in the treatment of spasmodic pains associated with gastritis, gastric ulcers and cholelithiasis. It has a role as an antispasmodic drug and a muscarinic antagonist. It is an organic bromide salt and a quaternary ammonium salt. It contains a butropium.
Manufacturing Process
To 100 ml of an isopropanol solution containing 11.8 grams of hyoscyamine
base were added drop by drop with stirring 10 ml of an isopropanol solution
containing 11 grams of p-n-butoxybenzyl bromide. After a while, the reaction
mixture had a turbid appearance followed by separation of white crystals.
After stirring for 5 hours at room temperature, the crystals were recovered by
filtration, which were then recrystallized from 120 ml of isopropanol. There
was obtained 15.8 grams of white needles having the melting point of 158°-
160°C.
Therapeutic Function
Spasmolytic
butropium bromide Preparation Products And Raw materials
butropium bromide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shaanxi Pioneer Biotech Co., Ltd. | 029-86629612 18202932191 | sales@pioneerbiotech.com | China | 337 | 55 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Shaanxi Dideu Newmaterial Co., Ltd. | 029-63373950 15353716720 | 1052@dideu.com | China | 10007 | 58 |
| Carbosynth | -- | sales@carbosynth.com | United Kingdom | 6018 | 58 |