ChemicalBook >> CAS DataBase List >>2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one structure

CAS No.: 74853-07-9

Chemical Name:: 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

Synonyms: Posaconazole inter-5;Posazonazole Intermediate 5;2,4-Dihydro-4-[4-[4-(4-methoxypheny;Posaconazole Methoxy Triazole Impurity;4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol;4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one;4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5-one;4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one;4-[4-[4-(4-Methoxyphenyl)piperazino]phenyl]-3,4-dihydro-2H-1,2,4-triazole-3-one;2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

CBNumber:: CB7930766

Molecular Formula:: C19H21N5O2

Molecular Weight:: 351.4

MDL Number:: MFCD02956606

MOL File:: 74853-07-9.mol

Last updated:2023-05-15 10:43:18

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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Properties

Melting point	270-277°C (dec.)
Density	1.30±0.1 g/cm3(Predicted)
vapor pressure	0-0Pa at 20-25℃
storage temp.	Sealed in dry,2-8°C
solubility	DMSO (Slightly, Heated)
pka	10.16±0.20(Predicted)
form	Solid:particulate/powder
LogP	2.3 at pH7
FDA UNII	69BLQ3QLT8

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P330-P501

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M266245	4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one	74853-07-9	10mg	$55	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0070321	2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE 95.00%	74853-07-9	10MG	$704.55	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0070321	2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE 95.00%	74853-07-9	100MG	$1593.9	2021-12-16	Buy
Alichem	74853079	4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one	74853-07-9	250mg	$235.62	2021-12-16	Buy
Chemenu	CM169541	2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one 95%	74853-07-9	1g	$557	2021-12-16	Buy

Product number	Packaging	Price	Buy
M266245	10mg	$55	Buy
CHM0070321	10MG	$704.55	Buy
CHM0070321	100MG	$1593.9	Buy
74853079	250mg	$235.62	Buy
CM169541	1g	$557	Buy

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one, is an intermediate for the synthesis of Itraconazole (I937500), an Antifungal.

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Suppliers

Global( 46)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19994	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Mainchem Co., Ltd.	--	sarah@mainchem.com	China	6572	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Career Henan Chemica Co	58
Labnetwork lnc.	58
LEAP CHEM CO., LTD.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Amadis Chemical Company Limited	58
Mainchem Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50

74853-07-9(2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one)Related Search:

Posaconazole Posaconazole Diastereoisomer 12 Posaconazole-d4 Posaconazole DiastereoisoMer interMediate 2 1H-1,2,4-TRIAZOLE, 1-[[(2S)-2-(2,4-DIFLUOROPHENYL)OXIRANYL]METHYL]-

Posaconazole-d5 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Itraconazole HYDROXY ITRACONAZOLE

SAPERCONAZOLE KETO ITRACONAZOLE 3H-1,2,4-TRIAZOL-3-ONE, 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-, (S)- ITRACONAZOLE-5-METHYL-2-ISOPENTANE MITRATAPID

BENZYL HYDROXY ITRACONAZOLE 3H-1,2,4-TRIAZOL-3-ONE, 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-, (R)- 2-SEC-BUTYL-D5-4-(4-[4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-2,4-DIHYDRO-[1,2,4]-TRIAZOL-3-ONE

1of4

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one 4-[4-[4-(4-Methoxyphenyl)piperazino]phenyl]-3,4-dihydro-2H-1,2,4-triazole-3-one Posaconazole inter-5 3H-1,2,4-Triazol-3-one,2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]- 4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5-one 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE(WXC08779) 4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one 2,4-Dihydro-4-[4-[4-(4-methoxypheny Posaconazole Methoxy Triazole Impurity 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazole-3- one Posazonazole Intermediate 5 4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol 74853-07-9 Intermediates & Fine Chemicals Pharmaceuticals