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CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P

CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P structure

CAS No.: 215923-54-9

Chemical Name:: CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P

Synonyms: GR 87;BDP 17;CX-546;BDP-17,CX546,GR87;CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P;1-(1,4-Benzodioxan-6-ylcarbonyl)piperidine;1-(2,3-Dihydro-1,4-benzodioxin-6-ylcarbonyl)piperidine;(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone;2,3-dihydro-1,4-benzodioxin-6-yl(piperidin-1-yl)methanone;Methanone,(2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl-

CBNumber:: CB7972429

Molecular Formula:: C14H17NO3

Molecular Weight:: 247.29

MDL Number:: MFCD01860868

MOL File:: 215923-54-9.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P Properties

Melting point	71-73°C
Boiling point	422.8±44.0 °C(Predicted)
Density	1?+-.0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: ≥10mg/mL
pka	-1.08±0.20(Predicted)
form	solid
color	white to off-white
FDA UNII	PV6YEC8983

SAFETY

Risk and Safety Statements

WGK Germany	3

CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	C271	CX546 ≥98% (HPLC), solid	215923-54-9	10mg	$277	2024-03-01	Buy
Sigma-Aldrich	C271	CX546 ≥98% (HPLC), solid	215923-54-9	50mg	$395.6	2024-03-01	Buy
Sigma-Aldrich	5.05016	CX546 - CAS 215923-54-9 - Calbiochem	215923-54-9	10MG	$188	2022-05-15	Buy
Tocris	2980	CX546 ≥99%(HPLC)	215923-54-9	10	$150	2021-12-16	Buy
Tocris	2980	CX546 ≥99%(HPLC)	215923-54-9	50	$585	2021-12-16	Buy

Product number	Packaging	Price	Buy
C271	10mg	$277	Buy
C271	50mg	$395.6	Buy
5.05016	10MG	$188	Buy
2980	10	$150	Buy
2980	50	$585	Buy

CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P Chemical Properties,Uses,Production

Uses

It is one of a series of AMPA modulators matergic AMPA receptors.

Uses

CX546 has been used as positive allosteric modulator for the glutamatergic receptor α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) in mice.

General Description

CX546, a benzoylpiperidine derivative ampakine is an analog of CX516.

Biological Activity

AMPA receptor potentiator. Binds specifically to the agonist bound non-desensitized receptor, most likely destabilizing the desensitized receptor conformation. Enhances cognitive function in rats.

Biochem/physiol Actions

CX546 has antipsychotic functionality and has the potential to treat schizophrenia. It improves the defects associated with the prepulse inhibition (PPI) and latent inhibition (LI)?in mice lacking metabotropic glutamate receptor type 5 (mGluR5). Additionally, CX546 potentiates synaptic plasticity, elicits neuroprotection and promotes the neurotrophin expression.

storage

Store at +4°C

CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P Preparation Products And Raw materials

Raw materials

Preparation Products

CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P Suppliers

Global( 86)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
InvivoChem	58
TargetMol Chemicals Inc.	58
GIHI CHEMICALS CO.,LIMITED	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-03	CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P 215923-54-9	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P
215923-54-9
US $1.00 / KG
99%
Career Henan Chemical Co

215923-54-9(CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P)Related Search:

3-Methylpiperidin-3-ol HCl 4-ETHOXY-N,N-DIETHYLBENZAMIDE 3-ethoxy-N,N-diethyl-4-hydroxybenzamide CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P CHEMBRDG-BB 5762406

(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(piperidin-1-yl)Methanone (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone BDP 17 GR 87 (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylMethanone CX 546 1-(2,3-Dihydro-1,4-benzodioxin-6-ylcarbonyl)piperidine 1-(1,4-Benzodioxan-6-ylcarbonyl)piperidine CX-546 BDP-17,CX546,GR87 Methanone,(2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl- CX546 (1-(1,4-BENZODIOXAN-6-YLCARBONYL)P 2,3-dihydro-1,4-benzodioxin-6-yl(piperidin-1-yl)methanone inhibit,CX-546,Autophagy,CX546,Inhibitor,CX 546,Ionotropic glutamate receptors,iGluR 215923-54-9 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals AMPA receptor potentiator which is specifically bound to agonist bound non-desensitized receptors.