ChemicalBook >> CAS DataBase List >>BENZAMIL HYDROCHLORIDE
BENZAMIL HYDROCHLORIDE
- CAS No.
- 161804-20-2
- Chemical Name:
- BENZAMIL HYDROCHLORIDE
- Synonyms
- Benzamil hydrochloride hydrate;Benzamil hydrate hydrochloride;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride;5-diamino-6-chloro-N-[imino[(phenylmethyl)amino]methyl]-2-pyrazinecarboxamide;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrate hydrochloride;3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide,hydrochloride;3;5-DIAMINO-6-CHLORO-N-[IMINO[(PHENYLMETHYL)AMINO]METHYL]-2-PYRAZINECARBOXAMIDE; MONOHYDROCHLORIDE
- CBNumber:
- CB7973022
- Molecular Formula:
- C13H15Cl2N7O
- Molecular Weight:
- 356.21
- MDL Number:
- MFCD00069219
- MOL File:
- 161804-20-2.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| storage temp. | 2-8°C |
|---|---|
| solubility | methanol: soluble10mg/mL |
| form | solid |
| color | yellow |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or may be stored at -20°C for up to 3 months. |
| FDA UNII | I7L324A070 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
BENZAMIL HYDROCHLORIDE price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B2417 | Benzamil hydrochloride hydrate ≥98% (HPLC) | 161804-20-2 | 10mg | $104 | 2024-03-01 | Buy |
| Sigma-Aldrich | B2417 | Benzamil hydrochloride hydrate ≥98% (HPLC) | 161804-20-2 | 50mg | $372 | 2024-03-01 | Buy |
| Cayman Chemical | 14313 | Benzamil (hydrochloride) | 161804-20-2 | 5mg | $43 | 2024-03-01 | Buy |
| Cayman Chemical | 14313 | Benzamil (hydrochloride) | 161804-20-2 | 10mg | $85 | 2024-03-01 | Buy |
| TRC | B183630 | BenzamilHydrochloride | 161804-20-2 | 10mg | $85 | 2021-12-16 | Buy |
BENZAMIL HYDROCHLORIDE Chemical Properties,Uses,Production
Description
Benzamil (161804-21-2) is a more potent (Ki = 10 nM vs 182 nM1, IC50 = 9 μM2) version of the epithelial sodium channel blocker Amiloride. It is also an inhibitor of Na+/Ca2+ exchange transport (IC50 = 11 μM)2 and the Na+/H+ antiporter (IC50 = 80 nM)2.
Uses
Benzamil Hydrochloride is a specific blocker of sodium channels. It also inhibits epithelial sodium channel (ENaC). Benzamil Hydrochloride is an analog of Amiloride (A578700).
Biochem/physiol Actions
Selective and potent blocker of Na+/H+ and Na+/Ca2+ channels
storage
Store at +4°C
References
Cuthbert and Fanelli (1978), Effects of some pyrazinecarboxamides on sodium transport in frog skin; J. Pharmacol. 63 139 Kleyman and Cragoe (1988), Amiloride and Its Analogs as Tools in the Study of Ion Transport; Membrane Biol. 105 1
BENZAMIL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 59)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| ZHIWE CHEMTECH CO LTD | 021-20221225 13917446399 | sales@zhiwe.net | China | 587 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Supplier | Advantage |
|---|---|
| ATK CHEMICAL COMPANY LIMITED | 60 |
| BOC Sciences | 58 |
| career henan chemical co | 58 |
| TargetMol Chemicals Inc. | 58 |
| Xi'an MC Biotech, Co., Ltd. | 58 |
| LEAP CHEM CO., LTD. | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | 58 |
| Aladdin Scientific | 58 |
| ZHIWE CHEMTECH CO LTD | 61 |
| MedChemexpress LLC | 58 |
View Lastest Price from BENZAMIL HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-02 | BENZAMIL HYDROCHLORIDE
161804-20-2
|
US $1.00 / KG | 1KG | 99%HPLC | 200KG | Career Henan Chemical Co |
-
- BENZAMIL HYDROCHLORIDE
161804-20-2
- US $1.00 / KG
- 99%HPLC
- Career Henan Chemical Co
161804-20-2(BENZAMIL HYDROCHLORIDE)Related Search:
Benzamil hydrate hydrochloride
N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrate hydrochloride
N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate
Benzamil hydrochloride hydrate
3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide,hydrochloride
3;5-DIAMINO-6-CHLORO-N-[IMINO[(PHENYLMETHYL)AMINO]METHYL]-2-PYRAZINECARBOXAMIDE; MONOHYDROCHLORIDE
5-diamino-6-chloro-N-[imino[(phenylmethyl)amino]methyl]-2-pyrazinecarboxamide
N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride
161804-20-2