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Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro-

Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro- structure

CAS No.: 509118-03-0

Chemical Name:: Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro-

Synonyms: Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro-

CBNumber:: CB810093722

Molecular Formula:: C23H25F2N5O

Molecular Weight:: 425.47

MDL Number:

MOL File:: 509118-03-0.mol

Last updated:2025-04-18 09:52:51

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Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro- Properties

Density	1.30±0.1 g/cm3(Predicted)
pka	13.02±0.40(Predicted)
FDA UNII	539503G9M0

Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro- Chemical Properties,Uses,Production

Uses

ATC0175 (free base) is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH-R1) with an IC50 value of 3.4 nM, as well as good selectivity over the Y5 and the α2A receptors. ATC0175 (free base) is promising for research of obesity[1].

References

[1] Kanuma K, et al. Lead optimization of 4-(dimethylamino)quinazolines, potent and selective antagonists for the melanin-concentrating hormone receptor 1. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3853-6. DOI:10.1016/j.bmcl.2005.05.121

Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro- Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	32281	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	19903	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	20660	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Lastest Price from Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-24	ATC0175 509118-03-0	US $2500.00-1980.00 / mg			10g	TargetMol Chemicals Inc.

ATC0175
509118-03-0
US $2500.00-1980.00 / mg
TargetMol Chemicals Inc.

Benzamide, N-[cis-4-[[4-(dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluoro- 509118-03-0 C23H25F2N5O