ChemicalBook >> CAS DataBase List >>Quinapril hydrochloride
Quinapril hydrochloride
- CAS No.
- 82586-55-8
- Chemical Name:
- Quinapril hydrochloride
- Synonyms
- ACCUPRIL;QUINAPRIL HCL;Korec;Conan;CI-906;Acupril;ccupril;ACCUPRO;Acequin;Acuitel
- CBNumber:
- CB8100984
- Molecular Formula:
- C25H31ClN2O5
- Molecular Weight:
- 474.98
- MDL Number:
- MFCD00889215
- MOL File:
- 82586-55-8.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:02:50
| Melting point | 120-130°C |
|---|---|
| alpha | D23 +14.5° (c = 1.2 in ethanol) (Klutchko); D25 +15.4° (c = 2 in methanol) (Goel, Krolls) |
| storage temp. | 2-8°C |
| solubility | H2O: >10mg/mL |
| form | solid |
| color | white |
| CAS DataBase Reference | 82586-55-8(CAS DataBase Reference) |
| FDA UNII | 33067B3N2M |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H303-H361 | |||||||||
| Precautionary statements | P201-P202-P270-P281-P301+P312-P308+P313-P403-P501c | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | NW7176000 | |||||||||
| HS Code | 2933492250 | |||||||||
| Toxicity | Freely sol in aq solvents. LD50 in male, female mice, rats (mg/kg): 1739, 1840, 4280, 3541 orally; 504, 523, 158, 107 i.v. (Kaplan, 1989) | |||||||||
| NFPA 704 |
|
Quinapril hydrochloride price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Q0632 | Quinapril hydrochloride ≥98% (HPLC), solid | 82586-55-8 | 250mg | $654 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP1193 | Quinapril hydrochloride British Pharmacopoeia (BP) Reference Standard | 82586-55-8 | 100MG | $229 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1593401 | Quinapril hydrochloride United States Pharmacopeia (USP) Reference Standard | 82586-55-8 | 400mg | $364.4 | 2024-03-01 | Buy |
| Alfa Aesar | J61913 | Quinapril hydrochloride, 98% | 82586-55-8 | 1g | $255.65 | 2024-03-01 | Buy |
| Alfa Aesar | J61913 | Quinapril hydrochloride, 98% | 82586-55-8 | 5g | $650.65 | 2024-03-01 | Buy |
Quinapril hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
Quinapril hydrochloride has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on renal tubular epithelial cell proliferation in human renal tubular epithelial cells. It has also been used as an ACE inhibitor to evaluate its effects on the expression of angiotensin II (AII) in patient-derived Atheroma samples.
Uses
Antihypertensive;Dopamine receptor agonist
Uses
Quinapril is an angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
Definition
ChEBI: Quinapril hydrochloride is a hydrochloride resulting from the reaction of equimolar amounts of quinapril and hydrogen chloride. A prodrug for quinaprilat hydrochloride (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. It has a role as an antihypertensive agent and an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It contains a quinapril(1+).
brand name
Accupril (Pfizer); Quinapril (Lupin); Quinapril (Ranbaxy) .
General Description
Quinapril hydrochloride,(S)-[(S)-N-[(S)21-carboxy3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid 1-ethyl ester hydrochloride(Acuretic), forms the diacid quinaprilate in thebody. It is more potent than captopril and equipotent to theactive form of enalapril.
Biochem/physiol Actions
Quinapril is a short-acting angiotensin converting enzyme (ACE) inhibitor.
Quinapril hydrochloride Preparation Products And Raw materials
Global( 286)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9320 | 58 |
| Hebei Lingding Biotechnology Co., Ltd. | +86-18031140164 +86-19933155420 | erin@hbldbiotech.com | China | 878 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
View Lastest Price from Quinapril hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-11-17 | Quinapril hydrochloride
82586-55-8
|
US $50.00 / kg | 1kg | 99% | 1 | Hebei Duling International Trade Co. LTD | |
 |
2022-02-25 | Quinapril hydrochloride
82586-55-8
|
US $99.00 / KG | 1KG | 99% | 1 ton | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2022-02-25 | Quinapril hydrochloride
82586-55-8
|
US $19.00 / KG | 1Kg/Bag | 99% | 20tons | Hong Kong Tiansheng New Material Trading Co., Ltd |
-
- Quinapril hydrochloride
82586-55-8
- US $50.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
-
- Quinapril hydrochloride
82586-55-8
- US $99.00 / KG
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-
- Quinapril hydrochloride
82586-55-8
- US $19.00 / KG
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
82586-55-8(Quinapril hydrochloride )Related Search:
Acupril
Korec
Korectic
Quinazil
ccupril
(3S-(2(R*(R*)),3R*))-2-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid monohydrochloride
(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride
(3S)-2-[(2S)-2-[[(1S)-1-carbethoxy-3-phenyl-propyl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenyl-butan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
Quinapril Hydrochloride (400 mg)
Quinapril hydrochlor
Quinapril hydrochloride (Accupril)
Quinapril HCl API
Conan
Naripshin
(3S)-2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, hydrochloride (1:1)
Quinapril for peak identification
Quinapril for system suitability
Quinapril hydrochloride, >=99%
3-isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-2-(2-((1-(ethoxycarbonyl)-3-p
monohydrochloride,(3s-(2(r*(r*)),3r*))-henylpropyl)amino)-1-oxopropyl)
CI-906
ACCUPRIN
ACCUPRO
(3S)-2-[(2S)-2-[[(1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMINO]-1-OXOPROPYL]-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID HYDROCHLORIDE
QUINAPRIL HYDROCHLORIDE
PD-109452-2
QUINAPRIL HYDROCHLORIDE, RELATED COMPOUND B3-ISOQUINOLINECARBOXYLIC ACID, 2-[2-[(1-CARBOXY-3-PHENYLPROPYL)AMINO]-1-OXOPROPYL]-1,2,3,4-TETRAHYDRO-,[3S-[2[R*(R*)],3R*]]- USP STANDARD
QUINAPRIL HYDROCHLORIDE, RELATED COMPOUND A ETHYL[3S-[2(R*),3A,11A BETA]]-1,3,4,6,11,11A-HEXAHYDRO-3-METHYL-1,4-DIOXO-ALPHA-(2-PHENYLETHYL)-2H-PYRAZINO[1,2-B]ISOQUINOLINE-2-ACETATE USP STANDARD
QuinaprilHclC25H30N205.HC1
CI-906, PD-109452-2, Accupril, Accuprin, Accupro
Accupron
3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, monohydrochloride, (3S)- (9CI)
3-Isoquinolinecarboxylic acid, 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, monohydrochloride, [3S-[2[R*(R*)],3R*]]-
Acequide
Acequin
Acuitel
Acuprel
(S)-2-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, 1-ethyl ester, monohydrochloride
(3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
Quinapril for system suitability CRS
Quinapril hydrochloride CRS
Quinapril for peak identification CRS
Quinapril hydrochloride USP/EP/BP
Quinapril HCl (CI-906)
WIDELY Quinapril HCL
Quinapril HydrochlorideQ: What is
Quinapril Hydrochloride Q: What is the CAS Number of
Quinapril Hydrochloride Q: What is the storage condition of
Quinapril Hydrochloride Q: What are the applications of
Quinapril Hydrochloride
Quinapril Hydrochloride (1593401)
(S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
ACCUPRIL
QUINAPRIL HCL
Acrylamide Impurity 5
82586-55-8
2586-55-8
C25H30N2O5HClC25H31ClN2O5
C25H31ClN2O5
C25H30N2O5ClH