Ampalex
- CAS No.
- 154235-83-3
- Chemical Name:
- Ampalex
- Synonyms
- CX 516;Ampalex;AMpakine CX516;Ampalex, >=98%;BDP-12(Ampalex);AMpalex (CX-516);CX516, 10 mM in DMSO;CX516; BDP 12; AMPAKINE CX516;SPD-420, BDP-12, CX-516, AMpalex;1-(6-Quinoxalinylcarbonyl)piperidine
- CBNumber:
- CB81011036
- Molecular Formula:
- C14H15N3O
- Molecular Weight:
- 241.29
- MDL Number:
- MFCD00943201
- MOL File:
- 154235-83-3.mol
- MSDS File:
- SDS
| Melting point | 88-90°C |
|---|---|
| Boiling point | 433.1±25.0 °C(Predicted) |
| Density | 1.236±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform, Methanol |
| pka | -0.14±0.30(Predicted) |
| form | powder |
| color | white to light brown |
| Water Solubility | H2O: 5mg/mL, clear |
| EWG's Food Scores | 1 |
| FDA UNII | Z5QU38B4V9 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| RTECS | TM2785170 | |||||||||
| NFPA 704 |
|
Ampalex price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1191 | CX516 ≥98% (HPLC) | 154235-83-3 | 5MG | $112 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML1191 | CX516 ≥98% (HPLC) | 154235-83-3 | 25MG | $438 | 2023-06-20 | Buy |
| Cayman Chemical | 14936 | BDP-12 ≥98% | 154235-83-3 | 5mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 14936 | BDP-12 ≥98% | 154235-83-3 | 10mg | $95 | 2024-03-01 | Buy |
| Cayman Chemical | 14936 | BDP-12 ≥98% | 154235-83-3 | 25mg | $200 | 2024-03-01 | Buy |
Ampalex Chemical Properties,Uses,Production
Chemical Properties
Tan Solid
Uses
Ampalex is a AMPA modulator that may exhibit therapeutic properties for treating Alzheimer''s disease, schizophrenia, and mild cognitive impairment (MCI) (1,2,3,4).
Uses
It is one of a series of AMPA modulators
Definition
ChEBI: CX-516 is a N-acylpiperidine.
Biochem/physiol Actions
CX516 is a positive allosteric modulator at AMPA receptor that inhibits the deactivation of AMPA receptors. CX-516 is a nootropic and ampakine agent.
in vivo
The specific extradimensional deficits produced by sub-chronic or early postnatal postnatal phencyclidine treatment were significantly attenuated by CX516 (10, and 20 mg/kg, s.c.)[1].
| Animal Model: | Male Lister Hooded rats (56-63 postnatal day)[1] |
| Dosage: | 5, 10, 20, and 40 mg/kg |
| Administration: | Subcutaneously |
| Result: | Two doses (10 and 20 mg/kg) were highly significant in improving the extradimensional shift deficit induced by either treatment regimes. Two doses (5 and 40 mg/kg) was ineffective at reversing the extradimensional impairment induced by the sub-chronic postnatal phencyclidine treatment regime. |
Ampalex Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29857 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32251 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9304 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
View Lastest Price from Ampalex manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-27 | CX516
154235-83-3
|
US $29.00-59.00 / mg | 99.82% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-07-13 | Ampalex
154235-83-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-10 | Ampalex
154235-83-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |