Isochlorogenic acid A
- CAS No.
- 2450-53-5
- Chemical Name:
- Isochlorogenic acid A
- Synonyms
- 3,5-Dicaffeoylquinic acid;3,5-CQA;CJ 4-16-4;Isochloric acid A;Isochlorogenic acid A;3,5-Dicaffeylquinic acid;ISOCHLOROGENIC ACID A(SH);3',5'-Isochlorogenic acid A;Quinic acid 3,5-di-O-caffeate;Isochlorogenic acid A, froM Lonicera japonica
- CBNumber:
- CB81040694
- Molecular Formula:
- C25H24O12
- Molecular Weight:
- 516.46
- MDL Number:
- MFCD00951290
- MOL File:
- 2450-53-5.mol
- MSDS File:
- SDS
| Melting point | >175°C (dec.) |
|---|---|
| Boiling point | 826.2±65.0 °C(Predicted) |
| Density | 1?+-.0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 3.54±0.50(Predicted) |
| form | Off-white to yellow/brown crystalline solid. |
| color | Off-White to Pale Yellow |
| Stability | Hygroscopic |
| InChIKey | KRZBCHWVBQOTNZ-PSEXTPKNSA-N |
| FDA UNII | ND94C5E75K |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| RTECS | GU8403966 |
| HS Code | 29189900 |
Isochlorogenic acid A price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00131 | 3,5-Di-caffeoylquinic acid ≥95% (LC/MS-ELSD) | 2450-53-5 | 1mg | $306 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL80426 | 3,5-Dicaffeoylquinic acid phyproof Reference Substance | 2450-53-5 | 10mg | $777 | 2024-03-01 | Buy |
| Cayman Chemical | 24964 | 3,5-Dicaffeoylquinic Acid ≥98% | 2450-53-5 | 5mg | $79 | 2024-03-01 | Buy |
| Cayman Chemical | 24964 | 3,5-Dicaffeoylquinic Acid ≥98% | 2450-53-5 | 10mg | $141 | 2024-03-01 | Buy |
| Cayman Chemical | 24964 | 3,5-Dicaffeoylquinic Acid ≥98% | 2450-53-5 | 25mg | $312 | 2024-03-01 | Buy |
Isochlorogenic acid A Chemical Properties,Uses,Production
Description
3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants. It has antioxidant, anti-inflammatory, and antiviral biological activities. 3,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC50 = 71.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF) and cytochalasin B (IC50 = 1.92 μM). It inhibits HIV-1 integrase 3''-end processing, strand transfer, and disintegration in a cell-free assay (IC50s = 0.33, 0.34, and 0.66 μg/ml, respectively) and inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED50 = 1 μg/ml). In vivo, 3,5-DCQA (25 mg/kg) protects mice from acute lung injury induced by LPS and decreases neutrophil count in bronchoalveolar lavage fluid (BALF).
Uses
Isochlorogenic Acid A is a phenolic compound shown to provide protection against oxidative stress cells. DNA protective agent.
Definition
ChEBI: 3,5-di-O-caffeoyl quinic acid is a carboxylic ester that is the diester obtained by the condensation of the hydroxy groups at positions 3 and 5 of (-)-quinic acid with the carboxy group of trans-caffeic acid. Isolated from Brazilian propolis and Suaeda glauca, it exhibits hepatoprotective and cytotoxic activities. It has a role as a metabolite, a hepatoprotective agent and an antineoplastic agent. It is a cyclitol carboxylic acid and a carboxylic ester. It is functionally related to a (-)-quinic acid and a trans-caffeic acid.
Isochlorogenic acid A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
View Lastest Price from Isochlorogenic acid A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-14 | Isochlorogenic acid A
2450-53-5
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
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- Isochlorogenic acid A
2450-53-5
- US $1.00 / KG
- 99%
- Career Henan Chemical Co