Quinupristin
- CAS No.
- 120138-50-3
- Chemical Name:
- Quinupristin
- Synonyms
- RP 68888;RP 57669;Antibiotic RP 57669;Quinupristin Mesylate;Quinupristin(RP-57669);Quinupristin Discontinued;Quinupristin/dalfopristin,Quinupristin,antibiotic,Quinupristin-dalfopristin,streptogramin,Inhibitor,Bacterial,inhibit;4-[4-(DiMethylaMino)-N-Methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]Methyl]-4-oxo-2-piperidinecarboxylic acid]virginiaMycin S1;Virginiamycin S1, 4-[4-(dimethylamino)-N-methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]methyl]-4-oxo-2-piperidinecarboxylic acid]-
- CBNumber:
- CB81073487
- Molecular Formula:
- C53H67N9O10S
- Molecular Weight:
- 1022.23
- MDL Number:
- MFCD00865105
- MOL File:
- 120138-50-3.mol
| Melting point | ~200° |
|---|---|
| FDA UNII | 91VAC8654E |
Quinupristin price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19764 | Quinupristin (mesylate) ≥98% | 120138-50-3 | 1mg | $255 | 2024-03-01 | Buy |
| Cayman Chemical | 19764 | Quinupristin (mesylate) ≥98% | 120138-50-3 | 5mg | $952 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0004691 | QUINUPRISTIN 95.00% | 120138-50-3 | 500MG | $1963.5 | 2021-12-16 | Buy |
| ApexBio Technology | C5450 | Quinupristin(mesylate) | 120138-50-3 | 1mg | $276 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004691 | QUINUPRISTIN 95.00% | 120138-50-3 | 50MG | $750.75 | 2021-12-16 | Buy |
Quinupristin Chemical Properties,Uses,Production
Description
Quinupristin is a streptogramin antibiotic that blocks peptide bond formation and peptide extension in bacteria. Quinupristin is usually combined with another streptogramin antibiotic, dalfopristin , to produce quinupristin-dalfopristin complex , known commercially as Synercid. While both quinupristin and dalfopristin have bacteriostatic effects, they act synergistically to kill Gram-positive bacteria, as well as some Gram-negative and anaerobic bacteria.
Uses
Quinupristin is a semi-synthetic analogue of virginiamycin B (ostreogrycin B, pristinamycin IA, streptogramin B) formed by a Mannich condensation and elimination to generate an exocyclic methylene alpha to the ketone of the 4-piperidinone. Addition of quinucidinylthiol to the methylene group affords quinupristin. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Quinupristin is used commercially in synergistic combination with dalfopristin (30:70). There is little published data on the synthesis, biological or antibiotic activity of quinupristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.
Uses
Quinupristin is a semi-synthetic analogue of virginiamycin B (ostreogyrcin B, pristinamycin IA, streptogramin B) formed by a Mannich condensation and elimination to generate an exocyclic methylene alpha to the ketone of the 4-piperidinone. Addition of quinucidinylthiol to the methylene group affords quinupristin. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Quinupristin is used commercially in synergistic combination with dalfopristin (30:70). There is little published data on the synthesis, biological or antibiotic activity of quinupristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.
Uses
Semisynthetic depsipeptide type I streptogramin. An antibacterial agent.
Quinupristin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shenzhen Shengda Pharma Limited | 755-85269922 +8613424394241 | sales@shengdapharm.com | CHINA | 310 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Hebei Duling International Trade Co. LTD | +8618032673083 | sales05@hbduling.cn | China | 15745 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
View Lastest Price from Quinupristin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-04-25 | Quinupristin
120138-50-3
|
US $100.00 / kg | 1kg | 99% | 100 tons | Hebei Duling International Trade Co. LTD |
-
- Quinupristin
120138-50-3
- US $100.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
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