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Tamsulosin hydrochloride

CAS No.
80223-99-0
Chemical Name:
Tamsulosin hydrochloride
Synonyms
EC-617;Tamsulosin Racemic;Tamuzosin hydrochloride;Tamsulosinehydrochloride;Tamsulosin hydrochloride;dl-Tamsulosin hydrochloride;ac Tamsulosin Hydrochloride;RaceMic TaMsulosin Hydrochloride;5-[(2RS)-2-[[2-(2-Ethoxyphenoxy)eth;Racemic Tamsulosin Hydrochloride (50 mg)
CBNumber:
CB81073674
Molecular Formula:
C20H29ClN2O5S
Molecular Weight:
444.97
MDL Number:
MFCD09954593
MOL File:
80223-99-0.mol
MSDS File:
SDS
Last updated:2023-05-15 10:42:50

Tamsulosin hydrochloride Properties

Melting point 254-256 °C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Pharmacokinetic data

Protein binding 99%
Excreted unchanged in urine 9%
Volume of distribution 0.2(L/kg)
Biological half-life 4-5.5 (M/R: 10-15) / Increased

SAFETY

Risk and Safety Statements

HS Code  2935909550

Tamsulosin hydrochloride price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000653 Tamsulosin Racemate European Pharmacopoeia (EP) Reference Standard 80223-99-0 y0000653 $220 2024-03-01 Buy
Sigma-Aldrich 1643281 Racemic tamsulosin hydrochloride United States Pharmacopeia (USP) Reference Standard 80223-99-0 50mg $2430 2024-03-01 Buy
TRC T006351 racTamsulosinHydrochloride 80223-99-0 100mg $1015 2021-12-16 Buy
Medical Isotopes, Inc. 72463 racTamsulosinHCl 80223-99-0 100mg $610 2021-12-16 Buy
Medical Isotopes, Inc. 72463 racTamsulosinHCl 80223-99-0 1g $725 2021-12-16 Buy
Product number Packaging Price Buy
Y0000653 y0000653 $220 Buy
1643281 50mg $2430 Buy
T006351 100mg $1015 Buy
72463 100mg $610 Buy
72463 1g $725 Buy

Tamsulosin hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

Tamsulosin hydrochloride is a specific ;1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.

Uses

Tamsulosin is a specific α1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.

Clinical Use

Treatment of benign prostatic hyperplasia

Drug interactions

Potentially hazardous interactions with other drugs
Anaesthetics: enhanced hypotensive effect.
Antidepressants: enhanced hypotensive effect with MAOIs.
Antifungals: concentration increased by ketoconazole.
Avanafil, vardenafil, sildenafil and tadalafil: enhanced hypotensive effect, avoid concomitant use.
Beta-blockers: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
Calcium-channel blockers: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
Diuretics: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
Moxisylyte: possibly severe postural hypotension.

Metabolism

Tamsulosin is metabolised slowly in the liver primarily by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4; it is excreted mainly in the urine as metabolites and some unchanged drug

Tamsulosin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 135)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213 info@longyupharma.com China 2531 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290 1056@dideu.com China 3734 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58

View Lastest Price from Tamsulosin hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tamsulosin hydrochloride pictures 2022-02-24 Tamsulosin hydrochloride
80223-99-0
US $99.99-77.77 / g 10g 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets,Customiz 1000kgs Shanghai Biolang Biotechnology Co., Ltd.
Tamsulosin hydrochloride pictures 2021-11-02 Tamsulosin hydrochloride
80223-99-0
US $5000.00 / KG 10KG EP 100KGS Baoji Guokang Healthchem co.,ltd
Tamsulosin hydrochloride pictures 2021-07-20 Tamsulosin hydrochloride
80223-99-0
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
  • Tamsulosin hydrochloride pictures
  • Tamsulosin hydrochloride
    80223-99-0
  • US $99.99-77.77 / g
  • 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets,Customiz
  • Shanghai Biolang Biotechnology Co., Ltd.
Tamsulosinehydrochloride Benzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, monohydrochloride (9CI) dl-Tamsulosin hydrochloride (-)-(R)-5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide hydrochloride Tamsulosin hydrochloride Tamuzosin hydrochloride EC-617 Racemic Tamsulosin Hydrochloride (50 mg) RaceMic TaMsulosin Hydrochloride ac Tamsulosin Hydrochloride 5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride Tamsulosin Impurity 12(Tamsulosin HCl Racemate) 5-[(2RS)-2-[[2-(2-Ethoxyphenoxy)eth Racemic Tamsulosin Hydrochloride (1643281) Tamsulosin Hydrochloride EP Impurity G as Racemate Hydrochloride Tamsulosin Racemic 80223-99-0 Intermediates & Fine Chemicals Isotope Labelled Compounds Pharmaceuticals