Pamidronic acid
- CAS No.
- 40391-99-9
- Chemical Name:
- Pamidronic acid
- Synonyms
- DLV;AHPrBP;Panolin;amidronate;Rescriptor;Pamidronicaci;PAMIDRONIC ACID;Iflab-bb F1977-0047;Delavirdine mesylate;Ibandronate Impurity 23
- CBNumber:
- CB8107554
- Molecular Formula:
- C3H11NO7P2
- Molecular Weight:
- 235.07
- MDL Number:
- MFCD00168777
- MOL File:
- 40391-99-9.mol
- MSDS File:
- SDS
| Melting point | 226-228°C |
|---|---|
| Boiling point | 658.7±65.0 °C(Predicted) |
| Density | 1.998±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Methanol (Very Slightly, Heated, Sonicated), Water (Slightly, Heated, Sonicated) |
| pka | 1.44±0.10(Predicted) |
| form | Solid |
| color | Light Brown to Beige |
| Stability | Hygroscopic |
| FDA UNII | OYY3447OMC |
| ATC code | M05BA03 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| HS Code | 9999999999 |
Pamidronic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 4149 | Delavirdine mesylate ≥99%(HPLC) | 40391-99-9 | 50 | $634 | 2021-12-16 | Buy |
| TRC | P172490 | PamidronicAcid | 40391-99-9 | 50mg | $105 | 2021-12-16 | Buy |
| Usbiological | 462007 | Pamidronic Acid | 40391-99-9 | 50mg | $368 | 2021-12-16 | Buy |
| AK Scientific | 2631AH | Pamidronicacid | 40391-99-9 | 1g | $158 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134480 | Pamidronic acid >99% | 40391-99-9 | 100mg | $510 | 2021-12-16 | Buy |
Pamidronic acid Chemical Properties,Uses,Production
Chemical Properties
White Solid
Originator
Aredia,Novartis,India
Uses
A biphosphonate bone resorption inhibitor.
Uses
anticancer
Definition
ChEBI: Pamidronate is a phosphonoacetic acid.
Manufacturing Process
For a batch size of 5 L, 587.5 g (3.2 moles) of mannitol is dissolved in 3.5 L of water. Pamidronic acid (31.6 g, 0.133 moles) is mixed with a 1.0 L aliquot of the mannitol solution to form a slurry. The slurry is then transferred into the remainder of the mannitol solution, and stirred for at least 15 min. Aqueous 1 N sodium hydroxide (270 ml) is then added and the mixture is stirred until a clear, colorless solution results. The pH is then adjusted to 6.50.1 using either 1 M aqueous phosphoric acid or 1 N aqueous sodium hydroxide, as needed. The solution is then filtered through a 0.22 micron filter, and filled at 20°C into vials at 4.0 ml (4.172 g)/vial, under sterile conditions. The aqueous solution is frozen at -37°C and lyophilized (20 mbar, 20°-40°C) to yield 1,250 vials, each containing 30 mg of amorphous disodium pamidronate. The vials are sealed under positive nitrogen pressure. The disodium pamidronate is amorphous (noncrystalline) by X-ray diffraction and contains 0.7 wt-% water.
brand name
Rescriptor (Agouron).
Therapeutic Function
Bone resorption suppressant
Pamidronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12377 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29627 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from Pamidronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-09-29 | Pamidronic acid
40391-99-9
|
US $1.00 / KG | 1KG | 98% | 10kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2021-07-29 | Pamidronic acid USP/EP/BP
40391-99-9
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
-
- Pamidronic acid
40391-99-9
- US $1.00 / KG
- 98%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Pamidronic acid USP/EP/BP
40391-99-9
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited