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ChemicalBook >> CAS DataBase List >>Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)-

Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)-

Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)- Structure
Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)- structure
CAS No.
2468783-75-5
Chemical Name:
Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)-
Synonyms
BAY-888;Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)-
CBNumber:
CB811207478
Molecular Formula:
C28H26FN5O2
Molecular Weight:
483.55
MDL Number:
MOL File:
2468783-75-5.mol
Last updated:2025-07-17 18:53:03
Request For Quotation

Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)- Properties

Boiling point 776.0±60.0 °C(Predicted)
Density 1.335±0.06 g/cm3(Predicted)
storage temp. Store at 2-8°C, protect from light
form Solid
pka 12.77±0.70(Predicted)
color Off-white to light brown

Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)- Chemical Properties,Uses,Production

Description

BAY-888 exhibits IC50 value of 1.5 nM and 5.5 nM towards CSNK1A1 and CSNK1D, respectively.

Uses

BAY-888 is an orally active CSNK1A1 and CSNK1D inhibitor with IC50 of 1.5 nM and 5.5 nM, respectively. BAY-888 has antitumor activity[1][2].

References

[1] Volker Schulze, et al. Substituted pyrrolo-pyridinone derivatives and therapeutic uses thereof. WO2022023337 A1.
[2] Steven M. Corsello, et al Abstract 3588: Discovery of potent and selective CSNK1A1 inhibitors for solid tumor therapy. Cancer Res 15 June 2022; 82 (12_Supplement): 3588.

Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19961 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 3193328036@qq.com China 29761 68
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29547 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

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Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BAY-888 pictures 2025-07-17 BAY-888
2468783-75-5
 US $0.00-0.00 / mg 10g TargetMol Chemicals Inc.
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    2468783-75-5
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Benzeneacetamide, 4-fluoro-α-methyl-N-[4-[4,5,6,7-tetrahydro-5-methyl-4-oxo-3-(phenylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]-2-pyridinyl]-, (αS)- BAY-888 2468783-75-5