Ecdysone
- CAS No.
- 3604-87-3
- Chemical Name:
- Ecdysone
- Synonyms
- ECDYSONE;A-ECDYSONE;Ecdyterone;α-Ecdysone;ALPHA-ECDYSON;ALPHA-ECYSONE;ALPHA-ECDYSONE;ECDYSONE, ALPHA-;ALPHA-ECDYSTERONE;α-Ecdysone ( >90%)
- CBNumber:
- CB8113524
- Molecular Formula:
- C27H44O6
- Molecular Weight:
- 464.63
- MDL Number:
- MFCD00042683
- MOL File:
- 3604-87-3.mol
| Melting point | 242°C |
|---|---|
| alpha | 20578 +62° |
| Boiling point | 488.1°C (rough estimate) |
| Density | 1.0493 (rough estimate) |
| refractive index | 1.4482 (estimate) |
| storage temp. | 2-8°C |
| solubility | Methanol (Very Slightly, Heated) |
| pka | 14.07±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Merck | 13,3525 |
| BRN | 2422986 |
| InChIKey | UPEZCKBFRMILAV-JMZLNJERSA-N |
| SMILES | [C@H]1(C[C@@]2([C@](C)(C[C@@H]1O)[C@]1([H])C([C@]3([C@@](CC1)(C)[C@@H]([C@H](C)[C@@H](CCC(C)(C)O)O)CC3)O)=CC2=O)[H])O |
| LogP | 0.870 (est) |
| CAS DataBase Reference | 3604-87-3(CAS DataBase Reference) |
| FDA UNII | RH692X7B7B |
Ecdysone price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E9004 | α-Ecdysone ≥90% | 3604-87-3 | 1mg | $189 | 2024-03-01 | Buy |
| Sigma-Aldrich | E9004 | α-Ecdysone ≥90% | 3604-87-3 | 5mg | $346.8 | 2024-03-01 | Buy |
| Cayman Chemical | 11711 | α-Ecdysone ≥95% | 3604-87-3 | 1mg | $53 | 2024-03-01 | Buy |
| Cayman Chemical | 11711 | α-Ecdysone ≥95% | 3604-87-3 | 5mg | $177 | 2024-03-01 | Buy |
| Sigma-Aldrich | E9004 | α-Ecdysone ≥90% | 3604-87-3 | 10mg | $992 | 2024-03-01 | Buy |
Ecdysone Chemical Properties,Uses,Production
Description
?Ecdysterone, also known as ecdysone or β-ecdysone, is a hormone that regulates the growth and development of insects. In 1954, Butenandt et al. isolated 250mg of the initial insect metamorphic active substance, ecdysone, from 500kg of silkworm pupae. Since then, various similar substances have been isolated from many plants. It has been found that ecdysteroids are not only more abundant in the plant kingdom compared to the animal kingdom, but also widely distributed and abundant in resources. Examples of ferns that contain ecdysteroids include Chinese cornbind, Sichuan cornbind, mulberry leaves, Dectenium heterocarpon, water plantain, Ginkgo biloba, yew, Thelypteris palustris, and Cyrtomium falcatum, among others.
Uses
α-Ecdysone is a steroidal prohormone.
Definition
ChEBI: Ecdysone is a 6-oxo steroid that is 5beta-cholest-7-en-6-one substituted by hydroxy groups at positions 2, 3, 14, 22 and 25 respectively (the 2beta, 3beta, 22R stereoisomer). It is a steroid prohormone of the major insect moulting hormone 20-hydroxyecdysone. It has a role as a prohormone. It is a 2beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid, a 6-oxo steroid, a 3beta-sterol and an ecdysteroid. It derives from a hydride of a 5beta-cholestane.
target
Sodium Channel | ATPase | Potassium Channel | Autophagy
Metabolic pathway
When white mice are administered 3H-ecdyson, (2b,3b,14a,22(R),25-pentahydroxy-5b-cholest-7-ene-6- one) by injection intraperitoneally, ecdysone is metabolized via hydroxylation at C14, followed by reduction of ring B into the 6a-hydroxy derivative and epimerization at C3.
storage
+4°C
Purification Methods
Recrystallise -ecdyson from tetrahydrofuran/pet ether and from H2O as a hydrate. It has been purified by chromatogaphy on Al2O3 and elution with EtOAc/MeOH. It has max at 242nm ( 12,400). Its acetate has m 214-216o from EtOAc/pet ether, and the 2,4-dinitrophenylhydrazone has m 170-175o(dec) from EtOAc. [Karlson & Hoffmeister Justus Liebigs Ann Chem 662 1 1963, Karlson Pure Appl Chem 14 75 1967, Beilstein 8 IV 3613.]
Ecdysone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | sales006@ingredients-lonier.com | China | 2596 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 269 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Hebei Runbin Biotechnology Co. LTD | 13180553332 | 2179877681@qq.com | CHINA | 996 | 58 |
| WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | +8615377521700 | wangwendy93@gmail.com | China | 868 | 58 |
View Lastest Price from Ecdysone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | Ecdyterone
3604-87-3
|
US $0.00 / MG | 20MG | ≥98% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2024-04-01 | Ecdysone
3604-87-3
|
US $0.00-0.00 / KG | 1KG | 99% | 5000 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2024-04-01 | Ecdysone
3604-87-3
|
US $0.00-0.00 / KG | 1KG | 99% | 5000 | Wuhan Haorong Biotechnology Co.,Ltd |
-
- Ecdyterone
3604-87-3
- US $0.00 / MG
- ≥98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Ecdysone
3604-87-3
- US $0.00-0.00 / KG
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Ecdysone
3604-87-3
- US $0.00-0.00 / KG
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd