Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate
![Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Structure](CAS/GIF/158913-22-5.gif)
- CAS No.
- 158913-22-5
- Chemical Name:
- Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate
- Synonyms
- SPDP-C6-NHS ester;N-succinimidyl 6-(3-(2-pyridyldithio)propionamido)hexanoate;2,5-dioxopyrrolidin-1-yl 6-(3-(pyridin-2-yldisulfaneyl)propanamido)hexanoate;(2,5-dioxopyrrolidin-1-yl) 6-[3-(2-pyridyldisulfanyl)propanoylamino]hexanoate;N-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3-(2-pyridinyldithio)propanaMide;Hexanoic acid, 6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB81176795
- Molecular Formula:
- C18H23N3O5S2
- Molecular Weight:
- 425.52
- MDL Number:
- MFCD00083163
- MOL File:
- 158913-22-5.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280-P271 |
| HS Code | 2928009090 |
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 803642 | LC-SPDP (succinimidyl 6-[3(2-pyridyldithio)propionamido]hexanoate) | 158913-22-5 | 50MG | $444 | 2024-03-01 | Buy |
| TRC | S691800 | Succinimidyl6-[3-(2-Pyridyldithio)propionamido]hexanoate | 158913-22-5 | 10mg | $170 | 2021-12-16 | Buy |
| AK Scientific | 7726AH | Succinimidyl6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | 50mg | $293 | 2021-12-16 | Buy |
| BroadPharm | BP-22651 | SPDP-C6-NHSester 90% | 158913-22-5 | 100mg | $380 | 2021-12-16 | Buy |
| AK Scientific | 7726AH | Succinimidyl6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | 100mg | $428 | 2021-12-16 | Buy |
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Chemical Properties,Uses,Production
Description
SPDP-C6-NHS ester contains a disulfide bond which is cleavable upon reduction. The NHS ester is reactive toward primary amine and sulfhydryl groups. SPDP-C6-NHS ester is commonly used for bioconjugation and reversible crosslinkings.
Chemical Properties
White Solid
Uses
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent.
General Description
The amine-reactive portion of SPDP reagents is the N-hydroxysuccinimide (NHS) ester. Reactions are most commonly performed in phosphate, carbonate/bicarbonate, or borate buffers at pH 7-8. Other buffers can be used provided they do not contain primary amines (or thiols or disulfide reducing reagents – see discussion of the sulfhydryl reactivity). The rate of reaction and degradation by hydrolysis increases with increasing pH; for example, the half-life of the NHS ester is several hours at pH 7 and less than 10 minutes at pH 9. NHS-ester reagents like SPDP and LC-SPDP have limited aqueous solubility and must be dissolved in organic solvent before adding them to a reaction mixture. Sulfo-NHS-ester reagents like Sulfo-LC-SPDP are water-soluble and can be added directly to aqueous reaction mixtures.
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Preparation Products And Raw materials
Raw materials
Preparation Products
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2893 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 | cb6@aikonchem.com | China | 16687 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4955 | 58 |
| Shanghai Benso Pharmaceutical Technology Co., Ltd. | 15088289376 | 248775804@qq.com | China | 4973 | 58 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3237 | 58 |
View Lastest Price from Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-21 | SPDP-C6-NHS ester
158913-22-5
|
US $0.00 / mg | 50mg | >99.00% | 50mg | Xian confluore Biological Technology Co., Ltd. |
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- SPDP-C6-NHS ester
158913-22-5
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.