ChemicalBook >> CAS DataBase List >>Hydrocortisone

Hydrocortisone

CAS No.
74050-20-7
Chemical Name:
Hydrocortisone
Synonyms
hydrocortisone aceponate;Methylprednisolone Impurity 45;Hydrocortisone 17-Propionate 21-Acetate;Efficort;Suniderma;Hydrocortisonepropylacetate;Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-17-(1-oxopropoxy)-, (11β)-;[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate;[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate;propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester
CBNumber:
CB81178906
Molecular Formula:
C26H36O7
Molecular Weight:
460.56
MDL Number:
MFCD00866010
MOL File:
74050-20-7.mol
Last updated:2023-09-04 15:51:00

Hydrocortisone Properties

Melting point 144-146°C
Density 1.23±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White to Pale Beige
FDA UNII 2340UP1L2G
ATC code D07AC16

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H360
NFPA 704
0
2 0

Hydrocortisone price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H714628 Hydrocortisone17-Propionate21-Acetate 74050-20-7 50mg $175 2021-12-16 Buy
TRC H714628 Hydrocortisone17-Propionate21-Acetate 74050-20-7 100mg $320 2021-12-16 Buy
TRC H714628 Hydrocortisone17-Propionate21-Acetate 74050-20-7 25mg $120 2021-12-16 Buy
Biosynth Carbosynth FH23886 Hydrocortisone 17-propionate 21-acetate 74050-20-7 10mg $88 2021-12-16 Buy
Biosynth Carbosynth FH23886 Hydrocortisone 17-propionate 21-acetate 74050-20-7 250mg $1040 2021-12-16 Buy
Product number Packaging Price Buy
H714628 50mg $175 Buy
H714628 100mg $320 Buy
H714628 25mg $120 Buy
FH23886 10mg $88 Buy
FH23886 250mg $1040 Buy

Hydrocortisone Chemical Properties,Uses,Production

Description

Hydrocortisone aceponate is the 17-a-propionate derivative of hydrocortisone-21-acetate. Its is reportedly significantly superior to the latter in the treatment of dermatoses of varying severity.

Chemical Properties

White to Off-White Solid

Originator

Beiersdorf (W.Germany)

Uses

A new topical hydrocortisone derivative with esterification in positions 17 and 21, inhibit the incorporation of [3H]thymidine in DNA in human skin fibroblasts less strongly than the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. Glucocorticosteroid.

Definition

ChEBI: Hydrocortisone aceponate is a corticosteroid hormone.

brand name

Retef

Hydrocortisone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 63)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9320 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49999 58
Henan Allgreen Chemical Co.,LTD
+86-37155567971 +86-13633837469 info@allgreenchem.com China 5986 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Hangzhou Kehui Pharmaceutical Co.,Ltd 057187359773 18094707759 sales10@hzkehuipharma.com China 17 58

Hydrocortisone Spectrum

[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester Hydrocortisonepropylacetate Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-17-(1-oxopropoxy)-, (11β)- Efficort Suniderma hydrocortisone aceponate Hydrocortisone 17-Propionate 21-Acetate Methylprednisolone Impurity 45 74050-20-7 C26H36O7 Intermediates & Fine Chemicals Pharmaceuticals Steroids API