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Hydrocortisone

Hydrocortisone
Hydrocortisone structure
CAS No.
74050-20-7
Chemical Name:
Hydrocortisone
Synonyms
hydrocortisone aceponate;Hydrocortisone 17-Propionate 21-Acetate;[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate;[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate;propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester
CBNumber:
CB81178906
Molecular Formula:
C26H36O7
Formula Weight:
0
MOL File:
74050-20-7.mol

Hydrocortisone Properties

Melting point:
144-146°C
Density 
1.23±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
Refrigerator

Hydrocortisone Chemical Properties,Uses,Production

Description

Hydrocortisone aceponate is the 17-a-propionate derivative of hydrocortisone-21-acetate. Its is reportedly significantly superior to the latter in the treatment of dermatoses of varying severity.

Chemical Properties

White to Off-White Solid

Originator

Beiersdorf (W.Germany)

Uses

A new topical hydrocortisone derivative with esterification in positions 17 and 21, inhibit the incorporation of [3H]thymidine in DNA in human skin fibroblasts less strongly than the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. Glucocorticosteroid

brand name

Retef

Hydrocortisone Preparation Products And Raw materials

Raw materials

Preparation Products


Hydrocortisone Suppliers

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74050-20-7(Hydrocortisone)Related Search:


  • hydrocortisone aceponate
  • [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
  • [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
  • propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester
  • Hydrocortisone 17-Propionate 21-Acetate
  • 74050-20-7
  • C26H36O7
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
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