ISOXATHION
- CAS No.
- 18854-01-8
- Chemical Name:
- ISOXATHION
- Synonyms
- e-48;si-6711;KARPHOS;HSDB6692;HSDB 6692;HSDB-6692;ISOXATHION;Isoxathion 0.1;ISOXATHION STANDARD;Propargite Impurity 8
- CBNumber:
- CB8122146
- Molecular Formula:
- C13H16NO4PS
- Molecular Weight:
- 313.31
- MDL Number:
- MFCD00210313
- MOL File:
- 18854-01-8.mol
- MSDS File:
- SDS
| Melting point | <25℃ |
|---|---|
| Boiling point | 160°C (rough estimate) |
| Density | 1.48 g/ml |
| vapor pressure | <1.3 x 10-4 Pa (25 °C) |
| storage temp. | 0-6°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| Water Solubility | 1.9 mg l-1 (25 °C) |
| pka | -6.17±0.28(Predicted) |
| form | liquid |
| color | Colourless to Pale Yellow |
| Specific Gravity | 1.48 |
| BRN | 1222135 |
| EWG's Food Scores | 4 |
| FDA UNII | IRA3YFG6CX |
| EPA Substance Registry System | Isoxathion (18854-01-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311-H410 |
| Precautionary statements | P264-P270-P273-P280-P301+P310-P302+P352+P312 |
| Hazard Codes | T,N |
| Risk Statements | 24/25-50/53 |
| Safety Statements | 28-36/37-45-60-61 |
| RIDADR | 3018 |
| WGK Germany | 3 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29349990 |
ISOXATHION price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 76529 | Isoxathion analytical standard | 18854-01-8 | 25mg | $245 | 2022-05-15 | Buy |
| TRC | I917690 | Isoxathion | 18854-01-8 | 10mg | $720 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PST0000383 | ISOXATHION 98.00% | 18854-01-8 | 50ML | $2695 | 2021-12-16 | Buy |
| Adipogen Life Sciences | CDX-I0049-M500 | Isoxathion ≥98%(HPLC) | 18854-01-8 | 500mg | $565 | 2021-12-16 | Buy |
| Adipogen Life Sciences | CDX-I0049-M100 | Isoxathion ≥98%(HPLC) | 18854-01-8 | 100mg | $141 | 2021-12-16 | Buy |
ISOXATHION Chemical Properties,Uses,Production
Description
Isoxathion is a pale yellow liquid, bp 160 ?C/0.15 mm Hg, vp <0.133mPa (25 ?C). Solubility in water is 1.9 mg/L (25 ?C). It is readily soluble in most organic solvents. Log Kow = 3.88. It is unstable to alkali.
Uses
Isoxathion is used as a pesticide.
Uses
Isoxathion is used to control sucking pests, leaf miners and some chewing pests in a variety of fruit, vegetables and ornamental plants.
Definition
ChEBI: An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group is replaced by a 5-phenyl-1,2-oxazol-3-yl group.
Metabolic pathway
The principal route of isoxathion metabolism in soil, plants and mammals is by hydrolysis, probably via the oxon to 3-hydroxy-5-phenylisoxazole which is rapidly conjugated in both plants and rats. In soils, and to a lesser extent in plants and mammals, further metabolism of 3-hydroxy- 5-phenylisoxazole proceeds via opening of the isoxazole ring to give various metabolites of which benzoic acid is one of the more important. De-ethylation of the phosphate moiety has not been observed.
Metabolism
The principal degradation route of isoxathion in animals, plants, and soil is cleavage of P?O-isoxazole through oxidative desulfuration to the oxon followed by hydrolysis to 3-hydroxy-5-phenylisoxazole, which is conjugated in both plants and rats.
Degradation
Isoxathion is unstable to alkalis (PM). The hydrolysis product, 3-hydroxy- 5-phenylisoxazole (2), yielded 5-phenyl-3H-oxazolin-2-one (3) as the major photoproduct via a photolytic rearrangement (Nakagawa et al.,1974).
Toxicity evaluation
The acute oral LD50 for rats is 112 mg/kg. NOEL (2 yr) for rats is 1.2 mg/kg b.w. DT50 in soil is 9–40 d.
ISOXATHION Preparation Products And Raw materials
Raw materials
Preparation Products
ISOXATHION Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| VladaChem GmbH | +49-7246-3082843 | info@vladachem.de | Germany | 1860 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9309 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| BEST-REAGENT | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11726 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9725 | 55 |
| The future of Shanghai Industrial Co., Ltd. | 021-61552785 | sales@shshiji.com | China | 9552 | 55 |