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β-Muricholic Acid

CAS No.
2393-59-1
Chemical Name:
β-Muricholic Acid
Synonyms
6β;β-MCA;7β-triol;β-Muricholic Acid;5β-Cholanic Acid-3α;2H5]-β-Muricholic Acid;Ursodeoxycholic Acid Impurity 30;5β-CHOLANIC ACID-3α, 6β, 7β-TRIOL;βMuricholic Acid,β Muricholic Acid;3a,6b,7b-Trihydroxy-5b-cholanoic acid
CBNumber:
CB81235447
Molecular Formula:
C24H40O5
Molecular Weight:
408.58
MDL Number:
MFCD00271403
MOL File:
2393-59-1.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:04

β-Muricholic Acid Properties

Melting point 226 °C
Boiling point 565.7±40.0 °C(Predicted)
Density 1.184±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO (Slightly), Ethanol (Slightly,Sonicated), Methanol (Slightly), Water (Sligh
form powder
pka 4.76±0.10(Predicted)
color white to beige
optical activity [α]/D +59 to +65°, c = 0.1 in methanol

β-Muricholic Acid price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2372 β-Muricholic Acid ≥98% (HPLC) 2393-59-1 5mg $237 2024-03-01 Buy
Sigma-Aldrich SML2372 β-Muricholic Acid ≥98% (HPLC) 2393-59-1 25mg $334 2024-03-01 Buy
Cayman Chemical 20287 β-Muricholic Acid ≥95% 2393-59-1 1mg $117 2024-03-01 Buy
Cayman Chemical 20287 β-Muricholic Acid ≥95% 2393-59-1 5mg $404 2024-03-01 Buy
Cayman Chemical 20287 β-Muricholic Acid ≥95% 2393-59-1 10mg $750 2024-03-01 Buy
Product number Packaging Price Buy
SML2372 5mg $237 Buy
SML2372 25mg $334 Buy
20287 1mg $117 Buy
20287 5mg $404 Buy
20287 10mg $750 Buy

β-Muricholic Acid Chemical Properties,Uses,Production

Description

β-Muricholic acid (β-MCA) is a murine-specific primary bile acid. Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.

Uses

β-Muricholic Acid is an bile acid found in urine. β-Muricholic Acid has been used in studies of down regulation of transporter protein through ubiquitin dependent protein degradation.

Definition

ChEBI: Beta-muricholic acid is a member of the class of muricholic acids in which the hydroxy groups at positions 6 and 7 both have beta configuration. It is a member of muricholic acids, a 6beta-hydroxy steroid and a 7beta-hydroxy steroid. It is a conjugate acid of a beta-muricholate.

β-Muricholic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(3a,5b,6b,7b)-3,6,7-trihydroxy-Cholan-24-oic acid 3a,6b,7b-Trihydroxy-5b-cholanoic acid (3α,5β,6β,7β)-3,6,7-Trihydroxycholan-24-oic acid β-Muricholic Acid Ursodeoxycholic Acid Impurity 30 5β-Cholanic Acid-3α 7β-triol β-MCA 2H5]-β-Muricholic Acid βMuricholic Acid,β Muricholic Acid Cholan-24-oic acid, 3,6,7-trihydroxy-, (3α,5β,6β,7β)- 5β-CHOLANIC ACID-3α, 6β, 7β-TRIOL 2393-59-1 Pharmaceuticals, Intermediates & Fine Chemicals, Steroids