ANTI-ACTIVATING TRANSCRIPTION FACTOR 3 (ATF-3) N-TERMINAL
- CAS No.
- Chemical Name:
- ANTI-ACTIVATING TRANSCRIPTION FACTOR 3 (ATF-3) N-TERMINAL
- Synonyms
- ANTI-ATF-3;ANTI-ATF-3, N-TERMINAL, HUMAN;ANTI-ACTIVATING TRANSCRIPTION FACTOR3;Anti-ATF3 antibody produced in rabbit;ANTI-ACTIVATING TRANSCRIPTION FACTOR-3, N-TERMINAL, HUMAN;ANTI-ACTIVATING TRANSCRIPTION FACTOR 3 (ATF-3) N-TERMINAL;Anti-Activating transcription factor 3 antibody produced in rabbit;Anti-Cyclic AMP-dependent transcription factor ATF-3 antibody produced in rabbit
- CBNumber:
- CB8124726
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01092265
- MOL File:
- Mol file
ANTI-ACTIVATING TRANSCRIPTION FACTOR 3 (ATF-3) N-TERMINAL price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | HPA001562 | Anti-ATF3 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB2108283 | Anti-ATF3 antibody produced in rabbit affinity isolated antibody | 100μL | $524 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA001562 | Anti-ATF3 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy |
ANTI-ACTIVATING TRANSCRIPTION FACTOR 3 (ATF-3) N-TERMINAL Chemical Properties,Uses,Production
Uses
Anti-ATF3 antibody produced in rabbit has been used in:
- western blotting
- immunofluorescence
- immunohistochemical staining
- chromatin immunoprecipitation (ChIP)
General Description
Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. (provided by RefSeq)
Biochem/physiol Actions
This protein binds the cAMP response element (CRE) (consensus: 5′-GTGACGT[AC][AG]-3′), a sequence present in many viral and cellular promoters. ATF3 represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
ANTI-ACTIVATING TRANSCRIPTION FACTOR 3 (ATF-3) N-TERMINAL Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-ACTIVATING TRANSCRIPTION FACTOR 3 (ATF-3) N-TERMINAL Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7979 | 58 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
Shanghai Yiyan Biotechnology Co. , Ltd. | 58 |