Fosteabine sodium
- CAS No.
- 65093-40-5
- Chemical Name:
- Fosteabine sodium
- Synonyms
- Starasid;Fosteabine sodium;Cytarabin ocfosfate;Cytarabine ocfosfate;cytarabine ocphosfate;Cytarabine ocphosphate;1-[5-O-[Stearyloxy(sodiooxy)phosphinyl]-β-D-arabinofuranosyl]cytosine;4-Amino-1-[5-O-[(sodiooxy)(octadecyloxy)phosphinyl]-β-D-arabinofuranosyl]-1,2-dihydropyrimidin-2-one;2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy(octadecyloxy)phosphinyl]-β-D-arabinofuranosyl]-, monosodium salt
- CBNumber:
- CB81269888
- Molecular Formula:
- C27H49N3O8P.Na
- Molecular Weight:
- 597.661
- MDL Number:
- MOL File:
- 65093-40-5.mol
| FDA UNII | 3I7U8R8NWC |
|---|
Fosteabine sodium Chemical Properties,Uses,Production
Description
Cytarabine ocfosfate is the first orally active stearate derivative of cytarabine introduced for the treatment of certain types of malignancies including myelodysplastic syndromes that eventually evolve into acute leukemia. Cytarabine is one of the most effective drugs for treating acute myeloid leukemia but suffers from poor bioavailability. As a monophosphorylated analog of cytarabine, the title compound exhibits potent antitumor activity and slowly converts to cytarabine in the liver, releasing cytarabine into the bloodstream over a prolonged period. Cytarabine ocfosfate is effective by both parenteral and oral administration and, therefore, has an advantage over the parenteral form of cytarabine or its analogs. It should be noted that cytarabine ocfosfate has major side effects such as myelosuppression and gastrointestinal toxicity.
Originator
Yamasa (Japan)
Definition
ChEBI: Cytarabine ocfosphate is a pyrimidine ribonucleoside monophosphate.
brand name
Starasid
Fosteabine sodium Preparation Products And Raw materials
Raw materials
Preparation Products
Fosteabine sodium Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9980 | 58 |
| Supplier | Advantage |
|---|---|
| NewCan Biotech Limited | 58 |