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ADRENORPHIN

CAS No.
88377-68-8
Chemical Name:
ADRENORPHIN
Synonyms
METORPHIN;ADRENORPHIN;METORPHAMIDE;METORPHINAMIDE;adrenorphin amide;Adrenorphin(3TFA);Adrenorphin (human);ADRENORPHIN (BOVINE);Adrenorphin (metorphamide);Tyr-Gly-Gly-Phe-Arg-Arg-Val-NH2
CBNumber:
CB8129589
Molecular Formula:
C44H69N15O9S
Molecular Weight:
984.18
MDL Number:
MFCD00065523
MOL File:
88377-68-8.mol
MSDS File:
SDS
Last updated:2024-03-27 11:49:37

ADRENORPHIN Properties

Density 1.42±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility insoluble in EtOH; ≥48.7 mg/mL in H2O; ≥98.4 mg/mL in DMSO
form Solid
pka 9.97±0.15(Predicted)
Sequence H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2

SAFETY

Risk and Safety Statements

WGK Germany  3

ADRENORPHIN price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J66403 Adrenorphin 88377-68-8 1mg $48.5 2021-12-16 Buy
Alfa Aesar J66403 Adrenorphin 88377-68-8 5mg $166 2021-12-16 Buy
ApexBio Technology A1032 Adrenorphin 88377-68-8 25mg $175 2021-12-16 Buy
ChemScene CS-0027637 Adrenorphin 95.49% 88377-68-8 5mg $210 2021-12-16 Buy
American Custom Chemicals Corporation PEP0000414 ADRENORPHIN 95.00% 88377-68-8 1MG $597.89 2021-12-16 Buy
Product number Packaging Price Buy
J66403 1mg $48.5 Buy
J66403 5mg $166 Buy
A1032 25mg $175 Buy
CS-0027637 5mg $210 Buy
PEP0000414 1MG $597.89 Buy

ADRENORPHIN Chemical Properties,Uses,Production

Biological Activity

adrenorphin (metorphamide) is a potent inhibitor of nicotine-induced adrenaline and noradrenaline release with ic50 value of 10 μm [1].adrenorphin (metorphamide) is an endogenous, c-terminally amidated, opioid octapeptide (tyr-gly-gly-phe-met-arg-arg-val-nh2) that is produced from proteolytic cleavage of proenkephalin a and is widely distributed throughout the mammalian brain [2].adrenorphin (metorphamide) is selective nicotine-induced adrenaline and noradrenaline release inhibitor and has higher than 100-fold more potent than the reported nicotine-induced adrenaline and noradrenaline release inhibitor met5-enkephalin. when tested with bovine adrenal chromaffin cells, adrenorphin (metorphamide) showed inhibition on 5 μm nicotine-induced atp release by almost 50% at 5μm and the inhibition was not in a dose-dependent manner [1]. in bioassays and binding assays, metorphamide exhibited high μ-binding activity, as well as κ-binding activity with nearly half percent toμ-binding activity, while showed no activity on δ-binding [2].

References

[1]. marley, p.d., k.i. mitchelhill, and b.g. livett, metorphamide, a novel endogenous adrenal opioid peptide, inhibits nicotine-induced secretion from bovine adrenal chromaffin cells. brain res, 1986. 363(1): p. 10-7.
[2]. weber, e., et al., metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. proc natl acad sci u s a, 1983. 80(23): p. 7362-6.

ADRENORPHIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 91)Suppliers
Supplier Tel Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58

View Lastest Price from ADRENORPHIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ADRENORPHIN pictures 2020-02-19 ADRENORPHIN
88377-68-8
US $7.00 / KG 1KG 99% 100kg Career Henan Chemical Co
  • ADRENORPHIN pictures
  • ADRENORPHIN
    88377-68-8
  • US $7.00 / KG
  • 99%
  • Career Henan Chemical Co

ADRENORPHIN Spectrum

H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2 METORPHIN METORPHINAMIDE METORPHAMIDE ADRENORPHIN ADRENORPHIN (BOVINE) TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2 PROENKEPHALIN (206-213) (BOVINE) tyr-gly-gly-phe-met-arg-arg-val amide TYROSINE-GLYCINE-GLYCINE-PHENYLALANINE-METHIONINE-ARGININE- ARGININE-VALINE AMIDE) adrenorphin amide Metorphamide, Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val amide Tyr-Gly-Gly-Phe-Arg-Arg-Val-NH2 Adrenorphin (metorphamide) Adrenorphin(3TFA) L-Valinamide, L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl- Adrenorphin (human) Adrenorphin 3TFA(88377-68-8(free base)) Adrenorphin 3TFA(88377688(free base)),Adrenorphin 3TFA(88377 68 8(free base)) 88377-68-8 C44H69N15O9S C44H69N15O9S1 Peptide CancerBiology